Clinical trials: Pregnancy, Physical Activity
Epithelial Ovarian Cancer, Ovarian Cancer
Phase 1 Study of VT-101 in Advanced Ovarian Cancer
This Phase 1, open-label study will evaluate VT-101, an investigational small-molecule therapy, in adult women with advanced, recurrent, or relapsed epithelial ovarian cancer.
- Trial name
- NCT07905677
- Testing
- VT-101
- Volunteers
- 22 people
- Sponsor
- Michael J. Goodheart
Endometrial Cancer
Exercise and Healthy Diet or Standard Care in Patients in Remission From Stage I or Stage II Endometrial Cancer
RATIONALE: Participating in a diet and exercise program may improve the quality of life of overweight and obese patients who are in remission from endometrial cancer.
- Trial name
- NCT00732173
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Case Comprehensive Cancer Center
Interstitial Cystitis, Bladder Pain Syndrome
Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome
In this study, the efficacy of exercise to improve interstitial cystitis/bladder pain syndrome symptoms and quality of life will be investigated.
- Trial name
- IC/BPS (NCT05699551)
- Testing
- Exercise regimen
- Sponsor
- Wake Forest University Health Sciences
Pelvic Floor Disorder
Adapted Physical Activity Based On Trunk Stabilization And Pelvic Floor Education For Female Pelvic Floor Disorders
Pelvic floor disorders affect a substantial proportion of women worldwide and represent a significant public health concern due to their impact on physical function, quality of life, and psychosocial well-being.
- Trial name
- NCT07789977
- Testing
- Adapted Physical Activity and education
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Université de Strasbourg
Ckd-Mbd
Relationship Between Cardiopulmonary Exercise Testing and Ca-P in Chronic Kidney Disease (CKD)
Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease.
- Trial name
- NCT04013139
- Testing
- CPET
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetes, Gestational
A Novel Diet Approach to Combat Gestational Diabetes
There is an urgent need to implement novel diet approaches to combat the increasing rates of gestational diabetes mellitus (GDM).
- Trial name
- NCT03803072
- Testing
- time restricted eating (TRE)
- Where
- Norway
- Volunteers
- 32 people
- Sponsor
- Norwegian University of Science and Technology
Overactive Bladder, Overactive Bladder Syndrome
Comparison of Different Treatments for Overactive Bladder Syndrome
This study aims to investigate the effects of pelvic floor muscle exercises, electrical stimulation and taping in patients with overactive bladder
- Conditions
- Overactive Bladder, Overactive Bladder Syndrome, Overactive Detrusor
- Trial name
- NCT04197466
- Testing
- Pelvic Floor Exercise Group, Kinesio tape, Electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara Yildirim Beyazıt University
Bladder Cancer
DURvalumab in Combination With S-488210/S-488211 vAccine in Non-muscle Invasive Bladder CancEr
DURANCE is a two part, phase Ib/II, multi-centre study to assess the safety and activity of S-488210/S-488211 in combination with durvalumab, in patients with non-muscle invasive bladder cancer (NMIBC).
- Trial name
- DURANCE (NCT04106115)
- Testing
- Durvalumab, S-488210/S-488211
- Where
- 7 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- University College, London
Pregnancy Related, Diabetes
Exercise Timing and Gestational Diabetes
The aim of this study is to understand if the timing of exercise around food intake can help improve blood sugar management in pregnant individuals with diabetes.
- Conditions
- Pregnancy Related, Diabetes, Diabete Mellitus, Type 2 Diabetes
- Trial name
- NCT05256615
- Testing
- 30-minute walking intervention, 10-minute
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alberta
End-stage Renal Disease
The Feasibility and Safety of an Intradialytic Exercise Program: DIALY-SIZE
The primary aim of this pilot study is to evaluate the feasibility and safety of four different types of intradialytic exercise (exercise performed during dialysis) programs: resistance, aerobic, combined resistance and aerobic…
- Trial name
- NCT02234232
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Postpartum Depression, Pregnancy Related
Clinical Pilates and Prenatal Education on Perinatal Depressive Symptoms
This study evaluated whether a combined program of supervised Clinical Pilates Exercise and structured Prenatal Education, added to routine antenatal care, reduces perinatal depressive symptoms compared with routine antenatal…
- Conditions
- Postpartum Depression, Pregnancy Related, Low Back Pain, Labor Pain
- Trial name
- CPE-PE (NCT07647809)
- Testing
- Clinical Pilates Exercise, Prenatal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Low Back Pain
Combined Effects of Core Stability Exercises and Back Strengthening Exercises on Pregnancy-Induced Back Pain.
The study will be a Randomized controlled trial to check the combined effects of Core Stability Exercises with and without Back strengthening exercises in females with pregnancy-induced back pain, disability, and function so that…
- Trial name
- NCT06351267
- Testing
- Core Stability Exercises, Back Strengthening exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Bladder Cancer, Telomere Shortening
Lifestyle Change for Better Health
The goal of the research is to provide a first critical test of the novel scientific idea that a combined diet and exercise intervention may ameliorate shortening of leukocyte telomere length (LTL) in individuals with histories…
- Conditions
- Bladder Cancer, Telomere Shortening, Colorectal Adenoma
- Trial name
- LCBH (NCT03286699)
- Testing
- Dietary Intervention, Physical Activity Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pittsburgh
Prostate Cancer, Bladder Cancer
Project HERO: Health Empowerment & Recovery Outcomes
Project HERO is a 12-week study of the efficacy of Body Mind Training (BMT, i.e. Tai Chi and Qigong in this project) for reducing fatigue in male cancer survivors.
- Conditions
- Prostate Cancer, Bladder Cancer, Kidney Cancer, Colon Cancer
- Trial name
- HERO (NCT03345563)
- Testing
- Body Mind Training (BMT), Body Training (BT):, Usual Care (UC)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Rutgers, The State University of New Jersey
Healthy
Pregnancy 24/7 Offspring Study
There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for…
- Trial name
- NCT07172880
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kara Whitaker
Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tumors associated with Nectin-4…
- Conditions
- Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms
- Trial name
- NCT04561362
- Testing
- BT8009, Pembrolizumab
- Where
- 24 sites in United States, Canada and 4 more
- Volunteers
- 329 people
- Sponsor
- BicycleTx Limited
Head and Neck Squamous Cell Carcinoma, Melanoma Excluding Uveal Melanoma
Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of intravenous (IV) administration of XmAb808 in combination with pembrolizumab in subjects with selected advanced solid tumors and to…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Melanoma Excluding Uveal Melanoma, Non-small Cell Lung Cancer, Squamous or Non-squamous, Urothelial Carcinoma
- Trial name
- NCT05585034
- Testing
- XmAb®808, Keytruda® (pembrolizumab)
- Where
- 12 sites in United States
- Volunteers
- 60 people
- Sponsor
- Xencor, Inc.
Diabetes During Pregnancy, Pregnancy Complications
Effects of Leg Ergometer Versus Arm Ergometer on Blood Glucose, Exercise Tolerance, Weight, and Psychological Stress Among Gestational Diabetic Patients
The current study is a single-blind, parallel-group randomized controlled trial involving 108 participants with diabetes during pregnancy. The trial will compare leg ergometer with arm ergometer.
- Conditions
- Diabetes During Pregnancy, Pregnancy Complications, Pregnancy in Diabetes, Gestational Diabetes Mellitus (GDM)
- Trial name
- GDM (NCT07554287)
- Testing
- Leg Ergometer, Arm Ergometer
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pregnancy, Pre-term Premature Rupture of Membranes
Preterm Premature Rupture of Membranes (PPROM): Bed Rest Versus Activity Trial
The objective of this study is to determine, through a randomized clinical trial, whether bed rest is helpful for the management of pregnancies complicated by preterm premature rupture of membranes (PPROM).
- Trial name
- BRAT (NCT01544387)
- Testing
- Bed Rest, Activity
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Solid Tumor, Solid Tumor, Adult
A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors
The goal of the Dose Escalation phase of the study is to evaluate the safety, tolerability, and pharmacokinetics (PK) to determine the maximum tolerated dose (MTD) and/or preliminary recommended dose for expansion (RDE) of…
- Conditions
- Solid Tumor, Solid Tumor, Adult, Advanced Solid Tumor, Metastatic Tumor
- Trial name
- NCT06264921
- Testing
- NKT3447
- Where
- 8 sites in United States
- Volunteers
- 23 people
- Sponsor
- NiKang Therapeutics, Inc.
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