Clinical trials: Pregnancy, Physical Activity
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stress Urinary Incontinence
Study Electromyographic Activity of the Muscles of the Pelvic Floor Runners With Conventional Shoes and Minimalist.
JUSTIFICATION: Urinary incontinence is highly prevalent among women who play high impact sports such as running. that observed one of the possible reasons for this high prevalence is delayed activation of the pelvic floor in…
- Trial name
- minimalwomen (NCT04457141)
- Testing
- Effect of pelvic floor for the use of minimalist shoes versus shod in woman.
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Anovulation, Amenorrhea
Effects of Gynecological Age on LH Sensitivity to Energy Availability
The purpose of this experiment is to investigate whether the dependence of luteinizing hormone pulsatility on energy availability declines during adolescence.
- Conditions
- Anovulation, Amenorrhea, Infertility, Starvation
- Trial name
- NCT00260286
- Testing
- Energy availability
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ohio University
Pregnancy
Acute Effects of High Intensity Training in Pregnancy on Fetal Well-being and Blood Flow Distribution
Pregnant women are recommended to be physically active ≥150 min/week, but <15% of Norwegian women attain this goal. Several well-designed studies on lifestyle interventions focusing primarily on exercise training in…
- Trial name
- HITFLOW (NCT04288479)
- Testing
- Single high-intensity interval training session
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Norwegian University of Science and Technology
Urinary Bladder, Neurogenic
Ambulatory Closed-loop Stimulation for Bladder Control
Individuals with spinal cord injury (SCI) develop neurogenic detrusor overactivity (NDO), resulting in urinary incontinence, decreased bladder capacity, and reduced quality of life.
- Trial name
- NCT05740527
- Testing
- Noninvasive electrical stimulation of genital nerves
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- MetroHealth Medical Center
Advanced Solid Tumors, Ovarian Cancer
A Study of PHST001 in Advanced Solid Tumors
This is a multi-center, first-in-human (FIH), open-label, Phase 1a/1b dose escalation and dose expansion study to assess the safety, PK, pharmacodynamics, and antitumor activity of PHST001 monotherapy (Phase 1a) or in combination…
- Conditions
- Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer, Cholangiocarcinoma
- Trial name
- NCT06840886
- Testing
- PHST001, Paclitaxel, Topotecan
- Where
- 20 sites in United States
- Volunteers
- 426 people
- Sponsor
- Pheast Therapeutics
Preterm Birth
Hammock Positioning's Influence on the Electromyographic Activity in the Flexor Muscles in Newborn Preterm
The individual who is born premature, in addition to a CNS still in accelerated training suffers early loss of intrauterine restraint, conditions that promote hypotonia characteristic of premature birth.
- Trial name
- NCT02621996
- Testing
- hammock, containment nest
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Postpartum Depression
Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression
The purpose of this study is to examine the efficacy of the active interventions (exercise or wellness/support intervention) compared to usual care on the prevention of postpartum depression among women at risk for depression.
- Trial name
- HM2 (NCT01883479)
- Testing
- Exercise, Wellness/Support
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Uterine Contraction, Pregnancy
Comparative Study of the Propagation of Uterine Electrical Activity (EHG) in Pregnant Women During Pregnancy and During Labour
The original aspect of the methodology proposed for this study concerns the use of as many as 16 electrodes to study the propagation and coordination (or synchronization) of uterine contraction.
- Conditions
- Uterine Contraction, Pregnancy, Delivery, Obstetric
- Trial name
- PropEHG (NCT02814344)
- Testing
- Electrohysterography
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lower Urinary Tract Symptoms, Female Genitourinary Disease
Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women
The goal of this clinical trial is to evaluate whether vaginal 17β-estradiol effectively treats storage symptoms of lower urinary tract symptoms (LUTS) and enhances quality of life.
- Conditions
- Lower Urinary Tract Symptoms, Female Genitourinary Disease, Urinary Stress Incontinence, Urinary Urge Incontinence
- Trial name
- NCT06508944
- Testing
- vaginal 17 beta-estradiol, Behavioral modifications
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Chronic Kidney Disease Stage 3 and 4, Peripheral Artery Disease (PAD)
Exercise Activity to Improve Mobility in Patients With CKD and PAD
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.
- Trial name
- EXACT-CKDPAD (NCT06621264)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control (Standard treatment)
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Lymphedema of Leg, Cancer of Cervix
High Intensity Interval Training (HIIT) for Patients With Cancer-related Lymphedema in the Lower Limbs
The aim of the study is to explore the feasibility and safety of High Intensity Interval Training on a stationary bike for patients with lymphedema in the lower limbs and the role of compression garments during exercise.
- Conditions
- Lymphedema of Leg, Cancer of Cervix, Cancer, Ovarian, Cancer, Endometrial
- Trial name
- NCT03653819
- Testing
- First exercise session + compression, First exercise session - compression
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Herlev and Gentofte Hospital
Chronic Kidney Diseases, Sexual Dysfunction
Quality of Life and Sexual Life in Hemodialysis Patients: Effects of an Intradialytic Exercise Program
The aim of the study is to investigate whether an intradialytic exercise program can improve the quality of life, sexual function, and sexual satisfaction in patients undergoing hemodialysis.
- Trial name
- NCT05836675
- Testing
- Intradialytic exercise
- Where
- 2 sites in Mexico
- Volunteers
- 37 people
- Sponsor
- Universidad Autónoma de Yucatán
Diabetes, Chronic Kidney Failure
An Innovative Virtually Supervised Exercise for Dialysis Patients
Among patients with diabetes 35% suffer from chronic renal disease and may require dialysis or kidney replacement over time. Furthermore, in diabetics with end stage renal disease (ESRD) that require dialysis, the risk of foot…
- Conditions
- Diabetes, Chronic Kidney Failure, Hemodialysis Complication
- Trial name
- NCT03076528
- Testing
- Sensor-based interactive exercise (game-based exercise), Non-technology foot and ankle exercise program
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Gestational Diabetes, Glucose Intolerance
Postpartum Weight Loss and Exercise (PRIDE)
The overall objective of this pilot project is to test in 50 women with a history of gestational diabetes mellitus (GDM), the effectiveness and feasibility of an 8 month intensive lifestyle intervention to reduce the rate of…
- Trial name
- PRIDE (NCT01296516)
- Testing
- Non-intervention group, Face to face, Telehelath Group
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Pennington Biomedical Research Center
Urothelial Carcinoma, Renal Cell Carcinoma
A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors.
The objective of this study is to assess the overall response rate, evaluate the antitumor activity, and characterize the safety and tolerability of BGB-A445 alone or in combination with tislelizumab in participants With Advanced…
- Conditions
- Urothelial Carcinoma, Renal Cell Carcinoma, Melanoma, Non-mucosal Melanoma
- Trial name
- NCT05661955
- Testing
- BGB-A445, Tislelizumab
- Where
- 18 sites in China
- Volunteers
- 113 people
- Sponsor
- BeiGene
Urinary Incontinence, Stress, Urinary Incontinence, Urge
Combined Treatment for Mixed Incontinence
The overarching goal of this randomized trial is to estimate the effect of combined midurethral sling (MUS) and peri-operative behavioral/pelvic floor therapy (BPTx) compared to MUS alone on successful treatment of MUI symptoms…
- Trial name
- ESTEEM (NCT01959347)
- Testing
- Miduretheral Sling, Miduretheral Sling with behavioral/pelvic floor therapy
- Where
- 10 sites in United States
- Volunteers
- 480 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Chronic Kidney Disease
Low-protein Formula Supplements in Chronic Kidney Disease
Prospective randomized contorl study.Comparing clinical outcome between chronic kidney disease who were prescribed 6% low-protein nutrition supplement along with dietatian regular nutrition education and those without oral…
- Trial name
- NCT05318014
- Testing
- Intervention group, Regular nutrition education
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Taichung Veterans General Hospital
Chronic Kidney Disease
The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity
This study evaluates the effect of oral sodium bicarbonate treatment on the intrarenal renin-angiotensin-system in adult patients with a metabolic acidosis and chronic kidney disease.
- Trial name
- BIC (NCT02896309)
- Testing
- Sodium bicarbonate, Sodium chloride
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Erasmus Medical Center
Stress Urinary Incontinence, Pelvic Floor; Weak
Systematized Quality Exercise Alternatives for Stress Incontinence
This randomized controlled study evaluates the effect of home biofeedback compared to pelvic floor physical therapy for the treatment of stress urinary incontinence.
- Conditions
- Stress Urinary Incontinence, Pelvic Floor; Weak, Incontinence, Urinary, Quality of Life
- Trial name
- SQEASI (NCT03443687)
- Testing
- Pelvic Floor Physical Therapy, Home Biofeedback
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
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