Clinical trials: Pregnancy, Physical Activity
Gestational Diabetes
Lifestyle Intervention Program for Women With Gestational Diabetes or Gestational Impaired Glucose Tolerance
The purpose of this research study is to implement and evaluate a lifestyle program designed to help women who have high glucose levels during pregnancy make healthful diet and physical activity changes to lose weight.
- Trial name
- APPLES (NCT01489163)
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Kaiser Permanente
End-Stage Kidney Disease
Adding Receptive Music to Intradialytic Resistance Exercise in Adults Receiving Maintenance Hemodialysis
People receiving maintenance hemodialysis commonly experience reduced physical function and exercise capacity. Intradialytic resistance exercise may help preserve or improve physical function, while receptive music listening may…
- Trial name
- NCT07819331
- Testing
- Intradialytic Resistance Exercise, Receptive Music Listening
- Where
- Tunisia
- Volunteers
- 47 people
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Lifestyle, Physical Activity
Healthy Bellies - Intervention Program During Pregnancy on Women and Newborn
"Healthy Bellies" is an intervention program with pregnant women, based on the promotion of healthy lifestyles. It aims to evaluate the impact of the program in the health of both pregnant and newborn.
- Conditions
- Lifestyle, Physical Activity, Dietary Habits, Depressive Symptoms
- Trial name
- NCT03045237
- Testing
- physical exercises classes
- Where
- Portugal
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of Minho
Chronic Kidney Disease
Physical Exercise With Flow Restriction of the Forearm in Chronic Kidney Disease
The aim of this study is to analyze the effectiveness of physical exercise with blood flow restriction on the diameter and the flow of vessels, muscle strength and circumference of the forearm in patients with CKD prior to making…
- Trial name
- NCT02619968
- Testing
- experimental group
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
In the literature, studies about urinary symptoms after radical prostatectomy (RP) are generally focused on urinary incontinence (UI), and studies about sexual symptoms are focused on erectile dysfunction (ED).
- Trial name
- NCT06126874
- Testing
- Patient Education, Pelvic Floor Muscle Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Congenital Adrenal Hyperplasia, Healthy
Catecholamine Reserve and Exercise Tolerance in Healthy Volunteers and Patients With Congenital Adrenal Hyperplasia
This study will examine and compare the effects of intense exercise on the release of catecholamines in patients with congenital adrenal hyperplasia (CAH) and in healthy persons.
- Trial name
- NCT00011791
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stress Urinary Incontinence
MoVo-guided Traditional Chinese Kegel Exercises for Preventing Postpartum Urinary Incontinence.
The goal of this clinical trial is to determine whether a prenatal exercise program integrating Liuzijue qigong with traditional levator ani training, guided by the MoVo (Motivation-Volition) theory and delivered via a supervised…
- Trial name
- NCT07742202
- Testing
- Routine Verbal Instruction Group, App-Supervised Kegel Exercise Group, Liuzijue & Levator Ani Training Group
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yu xin Qian
Renal Failure, Renal Transplantation
A Reduced 11-b-HSD Activity, a Novel Mechanism of Salt Sensitivity and Hypertension After Renal Allograft Donation?
Consecutive living-kidney donor candidates (n=100) will be recruited after being accepted for donation according to official guidelines.
- Conditions
- Renal Failure, Renal Transplantation, Living Donors
- Trial name
- NCT01009229
- Testing
- Low and high salt diets
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Kidney Diseases
Aerobic Exercise in Patients With CKD
Patients with chronic kidney disease (CKD), especially those who are on dialysis, have a high prevalence of cardiovascular mortality and among the risk factors; inflammation and oxidative stress stand out.
- Trial name
- NCT04375553
- Testing
- Aerobic exercise
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal Fluminense
Ovarian Neoplasms
Study of the Combination Carboplatin Plus Celecoxib in Heavily Pre-treated Recurrent Ovarian Cancer Patients
The aim of this study is to evaluate the antitumor activity and potential adverse effects of the combination celecoxib plus carboplatin in patients with recurrent, heavily pre-treated Ovarian Cancer (OC).
- Trial name
- carbo-cox2 (NCT01124435)
- Testing
- Carboplatin plus Celecoxib
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Catholic University of the Sacred Heart
Gene Polymorphism, Edoxaban
Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency
1. To provide reference for clinical rational use of edoxaban; 2. Optimize the individualized dosing regimen of edoxaban.
- Conditions
- Gene Polymorphism, Edoxaban, Renal Insufficiency
- Trial name
- NCT06431789
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Yi Han
Atypical Hemolytic Uremic Syndrome
Complement Inhibition in aHUS Dialysis Patients
This study evaluates the effect of CCX168, a C5aR Antagonist, Oral Administration on Ex Vivo Thrombus Formation and Disease Activity in ten patients with diagnosis of Atypical Hemolytic Uremic Syndrome with or without genetic…
- Trial name
- ACCESS (NCT02464891)
- Testing
- CCX168
- Where
- Italy
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pregnancy
The Impact of Mobile Application-guided Physical Exercise on Physiological Parameters in Healthy Pregnant Women
After the second-trimester anomaly scan, healthy pregnant women will be offered inclusion in the study. Before inclusion, participants will fill out a questionnaire on the suitability of moderate physical exercise.
- Trial name
- NCT06722989
- Testing
- mobile-guided exercise, Unguided physical activity
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
New Born
Impact of Physical Activity During Pregnancy on Biological Markers at Birth in Cord Blood (CORDOMOUV)
Currently, an interventional protocol for physical activity during pregnancy is underway at the Clermont University Hospital (PREGMOUV study).
- Trial name
- CORDOMOUV (NCT07579468)
- Testing
- physical activity level during pregnancy
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pregnancy Outcome, Gestational Weight Gain
The Effect of Individualized Exercise Guidance on Pregnancy Outcome
A single center, randomized controlled trial was conducted to investigate whether individualized exercise guidance was more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Pregnancy Outcome, Gestational Weight Gain, Mediation, Macrosomia, Fetal
- Trial name
- NCT05760768
- Testing
- Individualized exercise guidance
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Solid Tumor, Advanced Solid Tumor
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
The goal of the Monotherapy Dose Escalation phase (Part 1) of the study is to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity to determine the preliminary recommended dose for…
- Conditions
- Solid Tumor, Advanced Solid Tumor, Solid Tumor, Adult, Metastatic Tumor
- Trial name
- NCT06586957
- Testing
- NKT3964, Paclitaxel, Doxorubicin
- Where
- 20 sites in United States, South Korea
- Volunteers
- 238 people
- Sponsor
- NiKang Therapeutics, Inc.
Labor Active Dilated Cm
Decision-Making in Labor Admission Using Transperineal Ultrasound vs. Vaginal Examination
This clinical trial aims to determine whether transperineal ultrasound (a perineal external scan) can improve decision-making for hospital admission in term pregnant women in labor compared to traditional vaginal examination.
- Trial name
- NCT07278271
- Testing
- Transperineal Ultrasound, Vaginal Examination
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Hospital Universitario La Paz
Pregnant Women, Exercise
PregFit Adventure: Strengthening Mothers-to-Be (PregFit)
1. Design. This will be a randomized clinical trial (RCT) with two groups, an experimental or intervention group and a control group. 2. Population, criteria, sample, calculation.
- Conditions
- Pregnant Women, Exercise, Game
- Trial name
- PregFit (NCT07041970)
- Testing
- Exergame
- Volunteers
- 84 people
- Sponsor
- University of Jaén
Kidney Cancer
Chemotherapy and Biological Therapy in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Biological therapies such as interferon alfa use different ways to stimulate the immune system and stop…
- Trial name
- NCT00045370
- Testing
- recombinant interferon alfa, temsirolimus
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Kidney Disease
Home-Based Exercise to Treat Decreased Physical Function in Patients With Varying Levels of Kidney Function
The investigators will conduct a pilot study to determine whether home-based exercise is an effective intervention to improve decreased physical function in kidney transplant candidates.
- Trial name
- NCT04745169
- Testing
- 8 week home-based exercise program
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine