Clinical trials: Pregnancy, completed
ESRD, Anticoagulant Toxicity
Apixaban in End-stage Kidney Disease : A Pharmacokinetics Study
Apixaban is a novel oral direct factor Xa inhibitor; In patients with atrial fibrillation, apixaban was superior to warfarin in preventing stroke or systemic embolism, caused less bleeding, and resulted in lower mortality (the…
- Trial name
- NCT03456648
- Testing
- apixaban
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bladder Cancer, Entire Ileal Conduit
Prehabilitation to Enhance Postoperative Functional Capacity Following Radical Cystectomy
The process of enhancing the functional capacity of an individual before an operation to enable him or her to withstand the stress of surgery has been termed prehabilitation.
- Conditions
- Bladder Cancer, Entire Ileal Conduit, Urinary Bladder Cancer
- Trial name
- NCT01836978
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Neoplasm Malignant, Breast Cancer
Shorter Scalp Cooling Time in Paclitaxel
Chemotherapy-induced alopecia (CIA) is one of the most distressing side effects for patients. Scalp cooling can prevent or minimise CIA in approximately half of all patients, depending on many factors, e.g.
- Conditions
- Neoplasm Malignant, Breast Cancer, Ovarian Cancer
- Trial name
- COP (NCT03266185)
- Testing
- Shorter PICT
- Where
- Netherlands
- Volunteers
- 91 people
- Sponsor
- Leiden University Medical Center
Diabetes, Gestational
Gestational Diabetes Mellitus Trial (GDM)
Gestational diabetes mellitus (GDM) is a type of diabetes (high blood sugar) that occurs in pregnant women. This study will determine whether treating pregnant women who have mild GDM improves the health of their babies.
- Trial name
- GDM (NCT00069576)
- Testing
- nutritional counseling, self blood glucose monitoring
- Where
- 16 sites in United States
- Volunteers
- 7,381 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Carcinoma, Renal Cell
Study of SU011248 in Patients With Advanced Kidney Cancer
To determine the objective tumor response of single-agent SU011248 at a dose of 50 mg orally once daily for 4 consecutive weeks and 2 weeks rest, repeated every 6 weeks in patients with metastatic Renal Cell Cancer (RCC).
- Trial name
- NCT00254540
- Testing
- SU011248 capsule
- Where
- 11 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Pfizer
Intubation; Difficult or Failed, Preterm Infant
New Intubation Method to Achieve Circulatory Stability and to Reduce Number of Intubation Attempts in Neonates
This is a randomized controlled pilot study investigating a new intubation method in newborn infants. In contrast to the conventional intubation method, in the new method the respirator is connected to the tube prior to insertion…
- Conditions
- Intubation; Difficult or Failed, Preterm Infant, Term Infant
- Trial name
- NOONA (NCT04089540)
- Testing
- New intubation method, Conventional intubation method
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Graz
Pregnancy Related
The Effect of the Use of Hand Massage Stimulation Techniques on the Hyperemesis Gravidarum
The aim of this study is to determine the effect of the use of hand massage stimulation techniques on nausea-vomiting severity and quality of life in pregnant women diagnosed with hyperemesis gravidarum.
- Trial name
- NCT07389668
- Testing
- seed therapy (su jok)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Inonu University
Bacterial Vaginoses
Treatment of BV With Donaxyl and a Molecular Test of Cure
. Treatment with dequalinium chloride vaginal tablets for 6 days had a cure rate lower than expected; only 37% of patients were considered cured one month after treatment.
- Trial name
- NCT04057482
- Testing
- D
- Volunteers
- 58 people
- Sponsor
- Skaraborg Hospital
Reproductive Effects, Pregnancy
Vitamin D and Pregnancy: Camden Study
Vitamin D is present in food either naturally or by fortification and included in nutritional supplements. It is also synthesized photochemically by the skin from ultraviolet B radiation.
- Trial name
- NCT02032459
- Where
- United States
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- Rowan University
Preterm Birth
Trial of the Use of Antenatal Corticosteroids in Developing Countries
Multi-country two-arm, parallel cluster randomized controlled trial to reduce neonatal mortality through increasing the rate of antenatal corticosteroid administration to eligible women.
- Trial name
- ACT (NCT01084096)
- Testing
- Increasing use of Antenatal Corticosteroids (ACS)
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 103,117 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Kidney Cancer
Interferon Alfa-2b With or Without Bevacizumab in Treating Patients With Advanced Renal Cell Carcinoma (Kidney Cancer)
RATIONALE: Biological therapies, such as interferon alfa-2b, may interfere with the growth of tumor cells. Bevacizumab may stop the growth of tumor cells by stopping blood flow to the tumor.
- Trial name
- NCT00072046
- Testing
- bevacizumab, recombinant interferon alfa
- Where
- 493 sites in United States, Canada
- Volunteers
- 732 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Uterine Cervical Neoplasms
Role of Bladder Training During Post-operative Hospital Stay After Radical Hysterectomy in Patients
The objective of the study is to evaluate the impact and the outcome of bladder training during post-operative hospital stay after radical hysterectomy, mainly after neoadjuvant concurrent chemo-radiation therapy for locally…
- Trial name
- NCT01907646
- Testing
- bladder training, No bladder training
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Catholic University of the Sacred Heart
Recurrent Renal Cell Cancer, Stage III Renal Cell Cancer
Interleukin-2 and Bryostatin 1 in Treating Patients With Advanced Kidney Cancer
Interleukin-2 may stimulate a person's white blood cells to kill tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Recurrent Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
- Trial name
- NCT00032188
- Testing
- aldesleukin, bryostatin 1, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Cancer Institute (NCI)
Infant, Premature
Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?
The purpose of this study is to find out which method (nasogastric vs. orogastric) of feeding tube for premature infants results in earlier only oral feeding.
- Trial name
- NCT00365703
- Testing
- Feeding tube insertion
- Where
- Israel
- Volunteers
- 115 people
- Sponsor
- Hillel Yaffe Medical Center
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Somatostatin in Polycystic Kidney: a Long-term Three Year Follow up Study
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary renal disease, responsible for 8% to 10% of the cases of end stage renal disease (ESRD) in Western countries.
- Trial name
- ALADIN (NCT00309283)
- Testing
- Long-acting somatostatin, Saline solution
- Where
- 5 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cancer
Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation
RATIONALE: Giving itraconazole or fluconazole may be effective in preventing infections in patients undergoing peripheral stem cell or bone marrow transplantation.
- Trial name
- NCT00003883
- Testing
- fluconazole, itraconazole
- Where
- 2 sites in United States
- Volunteers
- 578 people
- Sponsor
- Fred Hutchinson Cancer Center
Pregnancy Termination
We Experience: Perspectives on a Quality Abortion Care Experience: A Patient Centered Approach
The purpose of this study is to determine aspects of abortion care most important to the patient in creating a "high quality" abortion experience, to investigate patients' expectations of abortion care, and to explore provider…
- Trial name
- NCT02827474
- Testing
- Patient Interview, Provider Interview
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of New Mexico
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Endometriosis, Reproductive System Disorder
Developing an US-MRI Biomarker Fusion Model for Endometriosis
Single centre, prospective, observational, cohort study looking to develop a database representing the variability of disease and imaging seen in women with clinically diagnosed endometriosis, awaiting laparoscopic surgery.
- Trial name
- DEFEND (NCT04974710)
- Testing
- Outpatient MRI
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Perspectum
End Stage Renal Disease, Cardiovascular Diseases
Comparison of MCO HD on Markers of Vascular Health Compared With On-Line Haemodiafiltration
The aim of this study is to evaluate haemodialysis treatment using a medium cut-off dialysis membrane (Theranova) compared with on-line haemodiafiltration treatment with respect to markers of endothelial health (plasma…
- Conditions
- End Stage Renal Disease, Cardiovascular Diseases, Inflammation
- Trial name
- MoDal (NCT03510520)
- Testing
- Medium Cut-Off Haemodialysis, On-Line Haemodiafiltration
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Manchester University NHS Foundation Trust
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