Clinical trials: Pregnancy, completed
Diabetic Nephropathies
Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy
This is a multi-center, randomized, parallel study to evaluate effect of exenatide on 24h-UAER in patients with diabetic nephropathy. Screening will be made to select eligible participants before intervention.
- Trial name
- NCT02690883
- Testing
- Exenatide, Lispro
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Labor, Induction
Induction of Labor in Term Premature Rupture of Membranes: A Comparison Between Oxytocin and Dinoprostone Followed Six Hours Later by Oxytocin
Prelabor rupture of membranes (PROM) is most commonly defined as rupture of membranes before the onset of labor and occurs in 8% of term pregnancies.
- Conditions
- Labor, Induction, PROM (Pregnancy)
- Trial name
- NCT01099280
- Testing
- SYNPITAN FORT 5 IU, Propess,SYNPITAN FORT
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Pregnancy, Cannabis
Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use
This study will recruit 20 women who are high risk for prenatal cannabis use for a 12-week program of using the tracker and receiving a Lifestyle Physical Activity program.
- Trial name
- NCT05528380
- Testing
- LPA + Fitbit Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Graft Rejection
Study of Alemtuzumab Versus Anti-thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation
The purpose of this research study is to compare the effects of the two most commonly used anti-T cell induction agents(alemtuzumab and rabbit anti-thymocyte globulin) to prevent rejection in kidney and pancreas transplant…
- Trial name
- NCT00331162
- Testing
- Alemtuzumab, Anti-Thymocyte Globulin
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Wake Forest University Health Sciences
Advanced Cancer, Ovarian Cancer
COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies
Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of COM902 as monotherapy and in combination with COM701 in subjects with advanced…
- Conditions
- Advanced Cancer, Ovarian Cancer, Lung Cancer, Colon Cancer
- Trial name
- NCT04354246
- Testing
- Dose escalation: COM902 monotherapy., Evaluation of safety/tolerability: COM902 in combination with COM701 (both at the RDFE), Cohort expansion: COM902 (RDFE) monotherapy.
- Where
- 9 sites in United States
- Volunteers
- 94 people
- Sponsor
- Compugen Ltd
Chronic Kidney Diseases
Late Feasibility Study to Evaluate Safety and Efficacy of AWAK PD Device in Subjects With ESKD.
The goal of this late feasibility clinical trial is to evaluate the safety and effectiveness of the Automated Wearable Artificial Kidney (AWAK) peritoneal dialysis (PD) device in subjects with end-stage kidney disease.
- Trial name
- NCT05827588
- Testing
- AWAK PD
- Where
- Singapore
- Volunteers
- 12 people
- Sponsor
- AWAK Technologies Pte Ltd
Chronic Kidney Disease, Diabetes
Effects of Febuxostat on Adipokines and Kidney Disease in Diabetic Chronic Kidney Disease
Hyperuricemia is emerging as a risk factor for development of diabetes and metabolic syndrome. Recently, it was shown in in-vitro cell culture experiments that hyperuricemia induces redox-dependent signaling and oxidative stress…
- Trial name
- NCT01350388
- Testing
- Febuxostat
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Cancer of Kidney, Kidney Cancer
Safety Study With the Antibody, cG250, and Isotope, 124-Iodine, to Diagnose Patients With Renal Masses.
The purpose of this study is to see if an antibody (cG250) attached to a radioactive substance (Iodine-124) safely detects clear cell renal cancer in patients with kidney tumors scheduled for surgery.
- Conditions
- Cancer of Kidney, Kidney Cancer, Renal Cancer, Neoplasms, Kidney
- Trial name
- NCT00199888
- Testing
- 124-Iodine-cG250 (124I-cG250)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Ludwig Institute for Cancer Research
Preterm
Automated Versus Manual Oxygen Control in Preterm Babies on Respiratory Support
Babies admitted in the NICU (neonatal intensive care unit) frequently need supplemental oxygen to keep their oxygen saturation (SpO2) in target range (TR).
- Trial name
- NCT06622161
- Testing
- automated oxygen vs manual oxygen
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Aga Khan University Hospital, Pakistan
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice
Baby2Home (B2H) Mobile Health Application
The COVID-19 pandemic has transformed healthcare delivery; arguably, the fields of obstetrics and pediatrics have experienced some of the greatest changes as they have transitioned away from their role as a medical home and into…
- Conditions
- COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness
- Trial name
- NCT05595486
- Testing
- Baby2Home Mobile Application
- Where
- 2 sites in United States
- Volunteers
- 642 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Ovarian Cancer, Neoplasms, Ovarian
Second-Line Therapy Study For Potentially Platinum-Sensitive Relapsed Ovarian Cancer
This study was designed to find the most effective and safest doses of both HYCAMTIN and CARBOPLATIN that can be given for the treatment of ovarian cancer.
- Trial name
- NCT00316173
- Testing
- topotecan, CARBOPLATIN
- Where
- 22 sites in United States, Canada
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
Congenital Adrenal Hyperplasia
Effects of Pioglitazone in Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia, an autosomal recessive condition, is mainly caused by mutations in the gene 21-hydroxylase and is treated with glucocorticoids in a slightly supraphysiological dose.
- Trial name
- NCT00151710
- Testing
- Pioglitazone
- Where
- Netherlands
- Sponsor
- Radboud University Medical Center
Cervical Intraepithelial Neoplasia
Human Papillomavirus (HPV) Testing to Improve Cervical Cancer Screening in the Mississippi Delta
Background: Cancer of the cervix (bottom third of the uterus, or womb) can be prevented by regular Pap tests (also called Pap smears), which check for changes in the cells of the cervix.
- Trial name
- NCT00443313
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- National Cancer Institute (NCI)
Overactive Bladder (OAB), Premature (Early) Ejaculation
Effect of Antimuscarinic Treatment on Premature Ejaculation Severity in Men With Overactive Bladder: a Prospective Comparison With Mirabegron
Overactive bladder (OAB) is a condition characterized by involuntary bladder contractions. Antimuscarinic drugs are commonly used to treat OAB by blocking muscarinic receptors (M2 and M3) in the bladder.
- Conditions
- Overactive Bladder (OAB), Premature (Early) Ejaculation, Ejaculation Abnormal
- Trial name
- NCT07736560
- Testing
- Tolterodine, Mirabegron (beta3-adrenoceptor agonist)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Vasectomy Reversal
The Impact of Prednisone on Semen Parameters and Pregnancy Rates Post Vasectomy Reversal
1. Determine impact of prednisone on semen parameters post vasectomy reversal (evaluated both using prednisone as a combined cohort as well as via 3 separate protocols). 2.
- Trial name
- NCT04788823
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Chronic Kidney Diseases
Chronic Kidney Disease : Role of Biological Factors and Apolipoprotein L1 Encoding Gene (APOL1)
Chronic kidney disease (CKD) is a major global public health issue. The present project focuses on the role of apolipoprotein L1 (APOL1) in patients with stage 4 CKD (glomerular filtration rate between 15 and 29 mL/min/1.73 m²).
- Trial name
- APOL1 (NCT07288723)
- Where
- Guadeloupe
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Kidney Failure, Chronic
Evaluation of the Integrated Home Dialysis Model
The purpose of this study is to evaluate which home dialysis modality pattern (home hemodialysis [HHD], peritoneal dialysis [PD] or a combination of both, e.g.
- Trial name
- NCT02278159
- Testing
- Peritoneal dialysis, Home hemodialysis
- Volunteers
- 11,600 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Urinary Incontinence
VACS Device Clinical Study for Incontinence Treatment
Stress Urinary incontinence (SUI) is a common health condition in the female population. Mid-urethral slings (MUS) have proven to be effective in the treatment of female SUI.
- Trial name
- VACS-D (NCT06173180)
- Testing
- TOT, VACS-D
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Soranus ArGe ve Danismanlik Hizmetleri Sanayi Ticaret A.S.
Uterine Myoma, Persistent Post-menpausal Bleeding
Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management.
Local anesthetics (LA) are increasingly used for postoperative pain management. Speicifically, several studies have found benefit of LA injected intra-abdominally following abdominal hysterectomy.
- Conditions
- Uterine Myoma, Persistent Post-menpausal Bleeding, Uterine Cancer
- Trial name
- PoPuLAR (NCT01492179)
- Testing
- Normal saline, Intravenous Lidocaine, Intra-abdominal Lidocaine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Preterm Delivery, Neonatal Complications
Progestagens for the Tertiary Prophylaxis of Preterm Delivery
Objective: This trial would evaluate the clinical effectiveness of Progesterone(P) and 17-hydroxy Progesterone (17P) in reducing PTD, in symptomatic women at risk because of cervical shortening, in the present pregnancy.
- Trial name
- PROTECT (NCT01178788)
- Testing
- 17 alpha-hydroxy progesterone caproate, micronized Progesterone, Control
- Where
- Italy
- Volunteers
- 254 people
- Sponsor
- University of Modena and Reggio Emilia
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