Clinical trials: Pregnancy, completed
Pregnancy
Effect of Pilates and Kegel Exercises During Pregnancy
Urinary incontinence and fecal incontinence are common health problems in the postpartum period because of their effect on daily life and are likely to reduce quality of life.
- Trial name
- NCT06869538
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hitit University
Preeclampsia, Hypertension
Cardiac and Immune Cell Function in Preeclampsia
Preeclampsia is a multi-system vascular disease which affects 2-5% of pregnancies. It is also a risk factor for the development of cardiovascular disease later in life and a number of functional and structural cardiac changes…
- Conditions
- Preeclampsia, Hypertension, Pregnancy Induced Hypertension, Pregnancy Related
- Trial name
- NCT04508582
- Testing
- Cardiovascular magnetic resonance, Echocardiography, Blood test
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Clinical Pregnancy Rate, Ovulation Induction
Follicular Long GnRH Agonist Versus Antagonist Protocol in PCOS Women Undergoing in Vitro Fertilization
Pituitary down regulation is widely used during in vitro fertilization (IVF) procedures. It can suppress the spontaneous luteinizing hormone (LH) surge, and can also make follicles growth evenly.
- Conditions
- Clinical Pregnancy Rate, Ovulation Induction, IVF
- Trial name
- NCT02496754
- Testing
- GnRH-a, GnRH-anta
- Where
- China
- Volunteers
- 1,266 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Malaria, Pregnancy
Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
Malaria in pregnancy is potentially fatal to both the mother and the foetus particularly in the primigravidae. Implementation of appropriate control and preventive measures is challenged by the fact that malaria infection in…
- Trial name
- NCT00131703
- Testing
- Amodiaquine, Sulphadoxine-pyrimethamine, Chloroquine
- Volunteers
- 900 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Preterm Birth, Twin Pregnancy With Antenatal Problem
Prophylactic Cerclage for Twin Pregnancy With Shortened Cervix
This randomized controlled trial is aimed to evaluate pregnancy and neonatal outcomes in twin pregnancies, in which a cervical cerclage is placed due to the shortening of the cervix with or without visible fetal membranes.
- Conditions
- Preterm Birth, Twin Pregnancy With Antenatal Problem, Cervical Shortening
- Trial name
- NCT05338164
- Testing
- cervical cerclage
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pre-Exposure Prophylaxis, HIV Infections
Testing Implementation Strategies to Improve Delivery of PrEP for Pregnant and Postpartum Women in Kenya
This study tests strategies for improving PrEP implementation in maternal and child health clinics using an interrupted time series.
- Conditions
- Pre-Exposure Prophylaxis, HIV Infections, Pregnancy Related
- Trial name
- PrEPARE (NCT05482360)
- Testing
- PrEP Optimization Interventions
- Where
- Kenya
- Volunteers
- 5,173 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy Related, Pregnancy Loss
Massage as an Adjunct Approach to Care for Pregnant Women Who Have Experienced a Stillbirth
The goal of this mixed-methods single-arm study is to measure the feasibility of massage as an adjunct approach to care for pregnant women who have experienced a stillbirth.
- Trial name
- NCT05636553
- Testing
- Massage
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fogarty Sarah
Ongoing Pregnancy, In-vitro Fertilization
Evaluation of the Effect of Dietary PI and TAC on the Outcome of Pregnancy in In Vitro Fertilization Treatment
The aim of this study is to determine the relationship between dietary total antioxidant capacity, phytochemical index, inflammatory index, dietary polyphenol intake and ongoing pregnancy outcome in couples receiving IVF…
- Trial name
- NCT05882422
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Hacettepe University
Pregnancy, Sexually Transmitted Infections
Contraceptive Awareness and Reproductive Education
The long-term objectives of this research are to develop effective treatments to reduce unplanned pregnancy and Sexually Transmitted Infections (STIs) for a highly under-served at-risk youth population.
- Trial name
- NCT01627574
- Testing
- Motivational Intervention, Didactic Educational Intervention
- Where
- 5 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Castor Oil, Prolonged Pregnancy
Effectiveness of Castor Oil in Preventing Formal Induction of Labour in a Tertiary Institution
This study demonstrated that castor oil was effective in reducing the need for formal induction of labour and the administration-delivery interval with minimal maternal side-effects, at an initial dose of 30ml and single repeat…
- Trial name
- NCT06841939
- Testing
- castor oil, Water
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assumpta Nnenna Nweke
HIV-1-infection, Pregnancy Related
Dolutegravir in Pregnant HIV Mothers and Their Neonates
To evaluate dolutegravir (DTG) efficacy in women who present with untreated HIV in late pregnancy. An open-label, multi-centre randomised controlled trial of DTG vs efavirenz-based regimens for women commencing cART in late…
- Trial name
- DolPHIN-2 (NCT03249181)
- Testing
- Dolutegravir, Standard of Care (EFV + 2 NRTI backbone)
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 268 people
- Sponsor
- University of Liverpool
Embryo Development, Blastocyst IVF
Effects of Light vs. Heavy Paraffin Oil on Embryo Culture in IVF: A Prospective Study on Development and Pregnancy Rate
This prospective study aims to compare the effects of light and heavy paraffin oil in embryo culture during in vitro fertilization (IVF).
- Conditions
- Embryo Development, Blastocyst IVF, Pregnancy Rates, IVF
- Trial name
- NCT06838923
- Testing
- Light Paraffin Oil, Heavy Paraffin Oil
- Where
- Vietnam
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Hung Vuong Hospital
Pregnancy Related, Tobacco Smoking
Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Despite public campaigns to prevent cigarette smoking, it's about 20% of women who keep on smoking during pregnancy, exposing their fetus to prenatal tobacco adverse effects.
- Conditions
- Pregnancy Related, Tobacco Smoking, Lung Smokers, Newborn
- Trial name
- NCT03047967
- Testing
- lung function tests, Nasal brushing
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Chromosome Translocation, Genetic Disorders in Pregnancy
Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst
Blastocysts derived from patients seeking infertility treatment were generated by in vitro fertilization and embryo culture as previously described, and were evaluated using the Gardner system.
- Conditions
- Chromosome Translocation, Genetic Disorders in Pregnancy, Recurrent Miscarriage
- Trial name
- NCT05216068
- Testing
- NGS
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Pregnancy Related
TeamBaby - Safe, Digitally Supported Communication in Obstetrics and Gynecology
The purpose of this project with obstetric healthcare workers, pregnant women and their relatives is to improve communication between all parties involved in order to increase sustainable patient safety.
- Trial name
- TeamBaby (NCT03855735)
- Testing
- TeamBaby Online Communication Training (IG1) and TeamBaby Web-App Communication Training (IG2)
- Where
- 2 sites in Germany
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Gestational Hypertension, Preeclampsia
App-based Remote Blood Pressure Monitoring
Remote postpartum blood pressure monitoring program with text messages has been shown to increase adherence to recommended postpartum blood pressure checks among those with hypertension at discharge from birth hospitalization…
- Conditions
- Gestational Hypertension, Preeclampsia, Chronic Hypertension Complicating Pregnancy
- Trial name
- NCT05595629
- Testing
- App-based remote blood pressure monitoring, text-message based remote blood pressure monitoring
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Pregnancy, Gait Analysis
Effects of Pilates Exercises on Gait in Pregnant Women
The goal of this interventional study is to investigate how the gait parameters, pain, and posture of women who perform Pilates exercises during pregnancy are affected.
- Conditions
- Pregnancy, Gait Analysis, Pain
- Trial name
- NCT06683989
- Testing
- Pilates training, Prenatal care
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Selcan Suicmez
Pregnancy Related, Sleep
Effect of Pregnant Pıllow on Sleep and Comfort
One of the most special life events of the fertile period is pregnancy. Pregnancy causes many physiological, metabolic, mental and social changes.
- Conditions
- Pregnancy Related, Sleep, Comfort
- Trial name
- NCT05790018
- Testing
- PREGNANT PILLOW
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Amasya University
Autoimmune Diseases, Adverse Pregnancy Outcomes
A Post-marketing Observational Database Study Monitoring the Safety of CecolinⓇ
This study was a retrospective-prospective real-world study to assess the safety among females receiving the 2vHPV vaccine (CecolinⓇ).
- Trial name
- HPV-PRO-013 (NCT06824896)
- Where
- China
- Volunteers
- 1,322,084 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
Maternal Health, Pregnancy Complications
Wakobo-ti-Kodro: Improving Identification of Pregnancy at Risk of Obstetric Complications at Community Level
This project aims to improve maternal health indicators in a national context where the maternal mortality rate is one of the highest in the world.
- Trial name
- NCT06613867
- Testing
- Wakobotikodro
- Where
- Central African Republic
- Volunteers
- 1,857 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action