Clinical trials: Pregnancy, completed
Renal Cell Cancer
An Observational Study of Avastin (Bevacizumab) in Combination With Interferon Alpha-2a as First-Line Treatment in Patients With Advanced and/or Metastatic Renal Cell Carcinoma
This observational study will evaluate the safety and efficacy of Avastin (bevacizumab) in combination with interferon alpha-2a as first-line treatment in patients with advanced and/or metastatic renal cell carcinoma.
- Trial name
- NCT01351571
- Where
- 2 sites in India
- Volunteers
- 5 people
- Sponsor
- Hoffmann-La Roche
Urologic Neoplasms
A Phase 2 Trial of ALIMTA (Pemetrexed) Plus Gemcitabine in Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium
Definition: Patients with bladder cancer will be participating in this study for the treatment of abnormal cells in the bladder that have returned after initial treatment OR have moved to a new site in the body.
- Trial name
- NCT00034593
- Testing
- ALIMTA, gemcitabine
- Where
- 9 sites in Finland, France and 1 more
- Sponsor
- Eli Lilly and Company
Carcinoma, Renal Cell
CPG 7909 in Patients Wih Stage IV Renal Cell Cancer
CPG 7909 given alone to patients with renal cell cancer after their nephrectomy. CPG 7909 is as a subcutaneous injection once per week for up to 24 weeks. Up to 40 patients will be included in the study.
- Trial name
- NCT00043407
- Testing
- CPG 7909
- Volunteers
- 42 people
- Sponsor
- Pfizer
HIV and Hepatitis B Coinfection
TAF for HIV-HBV With Renal Dysfunction
The investigators aim at describing changes in renal glomerular and tubular function with after the switch from TDF to TAF in HIV/HBV-coinfected patients with mild to moderate renal dysfunction and to assess the virological…
- Trial name
- NCT03115736
- Testing
- Tenofovir Alafenamide
- Where
- 8 sites in Switzerland
- Volunteers
- 24 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
End-stage Renal Disease
Apixaban in Hemodialysis
This study aims to determine the effects of end-stage renal disease on the pharmacokinetics, pharmacodynamics, safety, and tolerability of apixaban. This is a single-center open-label pharmacological study.
- Trial name
- NCT02672709
- Testing
- apixaban
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Jewish General Hospital
Urinary Incontinence
Effect of Glutamine on Urinary Incontinence
The objective of this study is to determine to effect of additional oral glutamine to Kegel exercises on pelvic floor strength and clinical parameters of urinary incontinence in females with either urinary incontinence (stress…
- Trial name
- NCT03265509
- Testing
- glutamine supplementation, fantomalt supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Beta-thalassemia, Myelodysplastic Syndromes
Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias
The purpose of this study is to determine the effects of the oral iron chelator Deferasirox on liver iron content after one year of treatment in patients with iron overload from repeated blood transfusions.
- Conditions
- Beta-thalassemia, Myelodysplastic Syndromes, Fanconi Syndrome, Anemia, Diamond-Blackfan
- Trial name
- NCT00061763
- Testing
- Deferasirox
- Where
- 6 sites in United States
- Volunteers
- 175 people
- Sponsor
- Novartis Pharmaceuticals
Preterm Infant
Executive Functions and Preterm Children in 3 to 4 Year Old
Preterm children have a high risk for neurodevelopmental impairments. The impact on motor functions and neurosensory functions is demonstrated but the incidenceof executive functions is not described for preterm infants.
- Trial name
- NCT03700463
- Testing
- BRIEF parental survey
- Where
- France
- Volunteers
- 356 people
- Sponsor
- Nantes University Hospital
Lupus Nephritis
Evaluate the Safety of CS20AT04 Inj. in Subjects With Lupus Nephritis
The purpose of conducting phase 1 trial to evaluate the safety and tolerability of allogenic bone marrow-derived mesenchymal stem cells(CS20AT04) in subjects with lupus nephritis.
- Trial name
- NCT03174587
- Testing
- allogenic bone marrow derived mesenchymal stem cells
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Corestemchemon, Inc.
Birth; Prolonged
Acceptability Assessment of an Optimized Birthing Position
This qualitative study evaluates the acceptability of positioning pregnant women in labour in an optimized position, which consists in the hyperflexion of the legs and the loss of the lumbar lordosis.
- Trial name
- NCT04056793
- Testing
- Optimized birthing position
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Bacteriuria, Intermittent Catheterization
Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine
This a prospective, non-controlled, open, multi-center study evaluating the reduction of bacteriuria after bladder irrigation with chlorhexidine in spinal cord injured patients with chronic bacteriuria practicing intermittent…
- Trial name
- NCT01782404
- Testing
- Chlorhexidine
- Where
- 4 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Wellspect HealthCare
Chronic Kidney Disease Stage 5 (Dialysis Dependent)
A Randomized, Comparative, Open-label Study of IV Monofer® Administered as Maintenance Therapy by Single or Repeated Bolus Injections in Comparison With IV Iron Sucrose in Subjects With CKD-5D
The purpose of this study is to compare the efficacy and safety of intravenous iron isomaltoside 1000 with intravenous iron sucrose in patients suffering from Stage 5 Chronic Kidney Disease on Dialysis Therapy (CKD-5D).
- Trial name
- NCT01222884
- Testing
- Monofer, Iron sucrose
- Where
- India
- Volunteers
- 351 people
- Sponsor
- Pharmacosmos A/S
End Stage Renal Disease
Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A
The primary purpose of this study is to test the feasibility of trials which change the dialysate (dialysis bath prescription) of potassium and bicarbonate according to a standardized algorithm and according to the results of…
- Trial name
- RADAR-A (NCT03519347)
- Testing
- Potassium Removal Maximization, Potassium Gradient Minimization, Alkalosis Avoidance
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Pregnancy Rates
Different Strategies in Frozen IVF/ICSI Cycles
In the absence of robust contemporary data, investigators decided to perform a multicenter cohort study of various IVF centers, to compare the different modalities used for pregnancy rates following frozen-thawed embryo transfer…
- Trial name
- NCT03965949
- Testing
- Hormone Replacement cycle 1, Hormone Replacement cycle 2
- Where
- Greece
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Cystocele
Detrusor Underactivity and Bladder Outlet Obstruction in Women With Cystocele
Women with cystocele may be associated with detrusor underactivity (DU) or bladder outlet obstruction (BOO). However, the impact of cystocele repair on the rates of DU and BOO remained obscure.
- Trial name
- NCT04184128
- Testing
- Urodynamic study
- Where
- Taiwan
- Volunteers
- 623 people
- Sponsor
- National Taiwan University Hospital
Opioid Use Disorder, Pregnancy Related
Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People
This study involves testing how useful a technology-enhanced intervention is for pregnant people prescribed buprenorphine for the management of opioid use disorder.
- Trial name
- NCT06496230
- Testing
- Empowering Pregnant Women and People Receiving Medications for Opioid Use Disorder
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Hyperphosphatemia, End-stage Renal Disease
A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)
This study is to evaluates the safety and tolerability of Zerenex™ (ferric citrate) as a treatment for hyperphosphatemia in patients with End-Stage Renal Disease.
- Trial name
- NCT00648167
- Testing
- ferric citrate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Keryx Biopharmaceuticals
Gestational Diabetes, Pregestational Diabetes
Smartphone Utilization for Glucose Monitoring and Antenatal Reporting
This project will utilize MHealth technology to address the barriers providers and obstetric patients experience when reporting blood glucose results.
- Trial name
- SUGAR (NCT03504592)
- Testing
- Completion of Glucose logs
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Rochester
Focus Type 2 Diabetes Related Chronic Kidney Disease
Diabetic Kidney Disease: Influence of Exercise Therapy on Physical and Vascular Function.
The general objective is to investigate the effect of a 12 week walking exercise program on vascular endothelial function, arterial stiffness/compliance, and vascular health biomarkers in men and women with pre-dialysis type 2…
- Trial name
- DKD-EXT (NCT02112071)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Minnesota
Uterine Fibroids, Menorrhagia
Uterine Artery Embolization for Symptomatic Fibroids
This study will evaluate the safety, efficacy , quality of life and patient satisfaction of uterine artery embolization for the treatment of symptomatic uterine fibroids.
- Conditions
- Uterine Fibroids, Menorrhagia, Adenomyosis
- Trial name
- NCT00354471
- Testing
- Uterine Artery Embolization
- Where
- Canada
- Sponsor
- University of Manitoba
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