Clinical trials: Pregnancy Anemia
Glucosephosphate Dehydrogenase Deficiency, Hyperbilirubinemia
Phase II Randomized Study of Tin Mesoporphyrin for Neonatal Hyperbilirubinemia
OBJECTIVES: I. Compare the efficacy of preventive vs. therapeutic tin mesoporphyrin in direct Coombs' test-positive ABO hemolytic disease of the newborn and glucose-6-phosphate dehydrogenase deficiency in infants living in…
- Conditions
- Glucosephosphate Dehydrogenase Deficiency, Hyperbilirubinemia, Hemolytic Disease of Newborn
- Trial name
- NCT00004381
- Testing
- tin mesoporphyrin
- Where
- 2 sites in United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Chronic Renal Failure, Anaemia
Study of Erythropoietin (EPO) Administration Schedule
The purpose of this study is to compare the hemoglobin and hematocrit variability between once and three times weekly erythropoietin therapy for the anemia in patients with maintenance dialysis.
- Trial name
- NCT01111630
- Testing
- recomon (Epoetin Beta)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- JW Pharmaceutical
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta
Database of Monochorionic Pregnancies
The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.
- Conditions
- Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Twin; Complicating Pregnancy, Twin to Twin Transfusion Syndrome
- Trial name
- NCT05543499
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Miami
Renal Anemia
Neocytolysis in the Treatment of Renal Anemia With Erythropoieses Stimulating Agents (ESA)
The purpose of this study is to gain information on reticulocyte neocytolysis in patients treated with ESA with regard to different types of ESA.
- Trial name
- NCT01306409
- Testing
- cera, darbepoetin, epoetin-beta, ESA
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland
Anemia
FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease
This is a randomized, multicenter, open-label, active-controlled study of the treatment of anemia in subjects with CKD on dialysis, with treatment up to 52 weeks.
- Trial name
- NCT02652806
- Testing
- FG-4592, Epoetin Alfa
- Where
- 31 sites in China
- Volunteers
- 305 people
- Sponsor
- Kyntra Bio
Anemia, Endometrial Diseases
Proliferative Effects of Erythropoietin on Human Endometrium
The purpose of this study to assess the proliferative effects of erythropoetin on human endometrium tissue by measuring the endometrial thickness, uterine artery and subendometrial blood flow in postmenopausal women.
- Trial name
- NCT03060603
- Testing
- Erythropoietin
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anemia, Dialysis-dependent Chronic Kidney Disease
Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa
This is a Phase 2 open-label efficacy, safety, and pharmacokinetic/pharmacodynamic (PK/PD) study to evaluate oral Vadadustat for the treatment of anemia in hemodialysis participants converting from Epoetin Alfa therapy.
- Trial name
- FO2RWARD-2 (NCT03799627)
- Testing
- Vadadustat, Epoetin Alfa, Vadadustat TIW
- Where
- 41 sites in United States
- Volunteers
- 175 people
- Sponsor
- Akebia Therapeutics
Ovarian Cancer, Fallopian Tube Cancer
Newton Study (NEW Dosing MainTenance Therapy Ovarian CaNcer)
This study evaluates whether the adoption of the RADAR dosing strategy could further reduce treatment related toxicities improving the safety profile of niraparib.
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
- Trial name
- Newton (NCT03891576)
- Testing
- Niraparib
- Where
- 12 sites in Germany, Italy
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Preterm Infants
Effect of Iron-fortified TPN on Preterm Infants Anemia
The purpose of this study is to determine whether iron-fortified TPN is effective in the preventative and treatment of preterm infants. Preterm infants are at risk for anemia especially in preterm infants.
- Trial name
- NCT01813682
- Testing
- treatment group1, treatment group2
- Where
- China
- Volunteers
- 118 people
- Sponsor
- qingya tang
Thalassemia
Therapeutic Effect of Colla Corii Asini on Improving Anemia and Hemoglobin Composition in Pregnant Women With Thalassemia
Seventy-two pregnant patients diagnosed of minor or intermediate beta thalassemia with mild anemia were randomly assigned to treatment group and control group.
- Trial name
- NCT02772016
- Testing
- Colla corii asini
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yanfang Li
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant
This phase I/II trial studies whether stopping cyclosporine before mycophenolate mofetil is better at reducing the risk of life-threatening graft-versus-host disease (GVHD) than the previous approach where mycophenolate mofetil…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00078858
- Testing
- fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 37 people
- Sponsor
- Fred Hutchinson Cancer Center
Endometriosis
Visanne Post-approval Observational Study (VIPOS)
The study assesses safety aspects of Dienogest (DNG) 2mg/day (Visanne) used as endometriosis therapy and of other hormonal treatments for endometriosis.
- Trial name
- NCT01266421
- Where
- Germany
- Volunteers
- 27,840 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Asthma, Diabetes Mellitus
Coordinated HEalthcare for Complex Kids
The University of Illinois Health and Health Sciences System (UI Health) developed an integrated care management quality improvement model designed to provide comprehensive care coordination for Medicaid insured minority children…
- Conditions
- Asthma, Diabetes Mellitus, Sickle Cell Disease, Premature Birth
- Trial name
- CHECK (NCT04057521)
- Testing
- Care Coordination
- Volunteers
- 6,259 people
- Sponsor
- University of Illinois Chicago
Third Trimeser
Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt
This study aims to assess the knowledge, attitude, and practice (KAP) of third-trimester pregnant women toward self-medication in Assiut, Egypt.
- Trial name
- SM-PREG (NCT07273214)
- Testing
- Structured Questionnaire on Self-Medication During Pregnancy
- Volunteers
- 420 people
- Sponsor
- Assiut University
Fetal Growth Retardation, Low Birth Weight
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
The primary aim of the study is to evaluate the effect of fortified balanced energy and protein (BEP) supplementation vs. control (multiple micronutrient supplement, MMS) without targeting and with targeting (either by low…
- Conditions
- Fetal Growth Retardation, Low Birth Weight, Preterm Birth, Gestational Weight Gain
- Trial name
- Target-BEP (NCT05576207)
- Testing
- Balanced energy and protein supplement for pregnant women, Multiple Micronutrient Supplement for pregnant women
- Where
- Bangladesh
- Volunteers
- 3,390 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Anemia, Dietary Habits
Food Groups Associated With Anaemia in Pregnant Women
This study investigates the association between locally consumed food items with anemia among pregnant women, in Addis Ababa city, Ethiopia.
- Conditions
- Anemia, Dietary Habits, Food Habits
- Trial name
- NCT03251664
- Testing
- Food groups consumed
- Where
- Ethiopia
- Volunteers
- 592 people
- Sponsor
- Tehran University of Medical Sciences
Renal Anemia of Chronic Kidney Disease
A Study of YPEG-rhEPO in Patients Suffered From Anemia Due to Chronic Kidney Disease
The purpose of this study is to evaluate the effectiveness and safety of YPEG rhEPO, a recombinant human erythropoietin pegylated by Y shape polyethylene glycol, in patients with anemia due to Chronic Kidney Disease (CKD)…
- Trial name
- NCT04885647
- Testing
- YPEG-rhEPO
- Where
- 17 sites in China
- Volunteers
- 60 people
- Sponsor
- Xiamen Amoytop Biotech Co., Ltd.
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Fanconi Anemia Complementation Group A
Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A
This is an open-label Phase II clinical trial to evaluate the efficacy of a hematopoietic cell-based gene therapy for pediatric patients with Fanconi Anemia, subtype A (FA-A).
- Trial name
- NCT04069533
- Testing
- RP-L102
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 7 people
- Sponsor
- Rocket Pharmaceuticals Inc.