Clinical trials: Pregnancy Anemia
Iron Deficiency, Iron Deficiency Anemia
Impact of Iron/Folic Acid vs Folic Acid Supplements During Pregnancy on Maternal and Child Health
According to a national study in 2002, the prevalence of ID, IDA, and ID+IDA among pregnant women in China was 42.6%, 9.1%, and 61.7% respectively.
- Trial name
- NCT02221752
- Testing
- Ferrous Sulfate + folic acid, Folic acid
- Where
- China
- Volunteers
- 2,367 people
- Sponsor
- Zhao gengli
Prevention of Vitamin Deficiency During and/or Before Pregnancy
A Study to Gather Information About the Progress and Outcomes of Pregnancy in Women Using Various Vitamin Support Plans Before and During Pregnancy
This is an observational study in which data from the participants who will be taking different vitamin supplementation regimes before and during pregnancy.
- Trial name
- NCT05062044
- Testing
- Multivitamins (Elevit, BAY987808), Multivitamins (Elevit, BAY2906300), Multivitamins (Elevit, BAY987386)
- Where
- 3 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bayer
Anemia Ferropenic, Risk of Hemoconcentration (Iron Levels >130g/L)
Effectiveness of Adaptation of the Dose of Iron Supplementation in Pregnancy on Maternal-child Health. (ECLIPSES)
Currently, there is no consensus regarding iron supplementation dose that is most beneficial for maternal and offspring health during gestation. This deficit, or excess, of iron prejudices the mother-child wellbeing.
- Trial name
- (ECLIPSES) (NCT03196882)
- Testing
- 40mg/day of iron, 20mg/day of iron, 80mg/day of iron
- Where
- 2 sites in Spain
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Victoria Arija Val
Sickle Cell Disease, Pregnancy, High Risk
SCRIPT: Sickle Cell Risk in Pregnancy Tool
Sickle Cell Disease (SCD), common in persons of Black ancestry, affects the shape of hemoglobin, the oxygen-carrying part of red blood cells (RBC).
- Conditions
- Sickle Cell Disease, Pregnancy, High Risk, Pregnancy Complications
- Trial name
- SCRIPT (NCT06529042)
- Testing
- Non-Interventional
- Where
- 3 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Mount Sinai Hospital, Canada
Atypical Hemolytic-Uremic Syndrome
An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome
The record Primary purpose is to assess the efficacy of eculizumab in adult patients with Atypical Hemolytic- Uremic Syndrome (aHUS) to control Thrombotic Microangiopathy (TMA) as characterized by thrombocytopenia, hemolysis and…
- Trial name
- NCT01194973
- Testing
- Eculizumab
- Where
- 23 sites in United States, Belgium and 5 more
- Volunteers
- 44 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Anemia, Renal Insufficiency, Chronic
A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects
The purpose of this study is to evaluate the efficacy and safety of molidustat in non-dialysis subjects previously treated with Erythropoiesis-Stimulating Agents (ESAs)
- Trial name
- MIYABI ND-M (NCT03350347)
- Testing
- Molidustat (BAY85-3934), Darbepoetin alfa
- Where
- 59 sites in Japan
- Volunteers
- 164 people
- Sponsor
- Bayer
Breast Cancer, Ovarian Cancer
Counseling Interventions for BRCA 1/2 Cancer Susceptibility Testing
To evaluate two different ways of providing information about genetic testing for BRCA1 and BRCA2 alterations. The two forms of counseling are genetic counseling and enhanced informed consent which cover similar material but are…
- Trial name
- NCT00165152
- Testing
- Genetic Counseling, Informed Consent Counseling
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Dana-Farber Cancer Institute
Anaemia, Malaria
Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment
Malaria is one of the major causes of illness and mortality in Sub-Saharan Africa. In Ghana, malaria is the most important cause of morbidity and accounts for about 40% of outpatient contacts.
- Trial name
- NCT00258024
- Testing
- IPT-sulphadoxinepyrimethamine
- Where
- Ghana
- Volunteers
- 420 people
- Sponsor
- DBL -Institute for Health Research and Development
Anemia, Dialysis-Dependent Chronic Kidney Disease
Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)
A multicenter, randomized, open-label, active-controlled Phase 3 study for the correction or maintenance treatment of anemia in participants with incident dialysis-dependent chronic kidney disease (DD-CKD).
- Trial name
- NCT02865850
- Testing
- Vadadustat, Darbepoetin alfa
- Where
- 118 sites in United States, Argentina and 9 more
- Volunteers
- 369 people
- Sponsor
- Akebia Therapeutics
Hemolytic-Uremic Syndrome, Atypical
Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)
Eculizumab is an anti-C5 monoclonal antibody approved for rare diseases including atypical haemolytic-uraemic syndrome. The maintenance phase dosing regimen is identical for all adult patients but several studies have shown a…
- Trial name
- EspacECU (NCT04859608)
- Testing
- Spacing of Eculizumab infusions
- Where
- 18 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Tours
Periodontal Disease, Chronic Kidney Disease
The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients
Several studies revealed a direct relationship between the severity of periodontal inflammation and CRP (NHANES III, Dumitriu HT et al, 1998).
- Trial name
- PAROHEM (NCT01785355)
- Testing
- Dental treatment
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Anemia Working Group Romania
Anemia
Long Term Safety Study of (VIT45) Extension Study: Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease
The primary objective of this study is to evaluate the long term safety and tolerability of an iron maintenance dosing strategy utilizing VIT45 in the treatment of anemia of non-dialysis dependent chronic kidney disease…
- Trial name
- NCT00317226
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- American Regent, Inc.
Chronic Myeloproliferative Disorders, Kidney Cancer
Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia
RATIONALE: Giving low doses of chemotherapy before a donor stem cell transplant using stem cells that closely match the patient's stem cells, helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma
- Trial name
- NCT00295997
- Testing
- anti-thymocyte globulin, filgrastim, graft-versus-tumor induction therapy
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Thrombotic Thrombocytopenic Purpura, Hemolytic Uremic Syndrome
Rituximab in Patients With Relapsed or Refractory TTP-HUS
The general objective of this study is to assess the efficacy and safety of Rituximab in the management of patients with refractory or relapsed thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS).
- Trial name
- NCT00531089
- Testing
- Rituximab
- Where
- 11 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Hairy Cell Leukemia
US Post-Marketing Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)
This study is being conducted to satisfy a post-marketing requirement (PMR) to provide evidence characterizing 1) the safety of moxetumomab pasudotox-tdfk in patients who are 65 years of age and older and/or 2) the safety of…
- Trial name
- PROXY (NCT04125290)
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- AstraZeneca
Breast Cancer, Ovarian Cancer
Methods in Education for Breast Cancer Genetics
In 1997, the Genetics Department of the NCI Medicine Branch helped establish a breast cancer genetics program at the National Naval Medical Center s Breast Care Center.
- Trial name
- NCT00001806
- Testing
- Genetic Education and Counseling
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- National Cancer Institute (NCI)
End Stage Renal Failure, Anaemia
Effectiveness of a Biosimilar Epoetin Alfa in Stable 'End Stage Renal Failure'
This is a prospective, observational, non-inferior study in ESRF patients stable on Eprex who are switched to a Biosimilar Epoetin Alfa. Study plans to recrut 44 patients.
- Trial name
- NCT02341547
- Testing
- a Biosimilar Epoetin Alfa
- Volunteers
- 44 people
- Sponsor
- Penang Hospital, Malaysia
Carcinomas, Amyloidosis
B-Receptor Signaling in Cardiomyopathy
We hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether…
- Conditions
- Carcinomas, Amyloidosis, Anal Cancer, Anemia
- Trial name
- NCT01135849
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Daniel Bernstein
Pregnancy Anemia
Non-invasive Point-Of-Care Hemoglobin Testing In An Obstetric Population
Anemia is common during pregnancy due to increased metabolic rate and normal physiologic changes associated with pregnancy. Anemia during pregnancy has been associated with increased of adverse outcomes during delivery and the…
- Trial name
- NCT06521840
- Testing
- Masimo RAD 67
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Beth Israel Deaconess Medical Center
Atypical Hemolytic Uremic Syndrome
Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS
This is a multicenter, single arm, open-label, extension study to evaluate the long-term safety, tolerability, and efficacy of iptacopan in participants with aHUS.
- Trial name
- NCT05795140
- Testing
- Iptcaopan 200 mg
- Where
- 9 sites in Brazil, China and 4 more
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals