Clinical trials: Pregnancy Anemia
Ovarian Neoplasm
Study to Assess the Efficacy and Safety of a PARP Inhibitor for the Treatment of BRCA-positive Advanced Ovarian Cancer
The purpose of the study is to see if the drug KU 0059436 is effective and well tolerated in treating patients with measurable BRCA1- or BRCA2-positive advanced ovarian cancer and for whom no curative therapeutic option exists.
- Trial name
- ICEBERG 2 (NCT00494442)
- Testing
- KU-0059436 (AZD2281)(PARP inhibitor)
- Where
- 11 sites in United States, Australia and 3 more
- Volunteers
- 58 people
- Sponsor
- AstraZeneca
Anorexia, Thalassemia
Clinical Diagnosis of Teenagers Admitted to Pediatric Departments
This study intends to analyze the clinical characteristics of teenagers admitted to pediatric wards due to organic illness and non organic diagnosis, including patients suffering from chronic diseases and comorbidity.
- Conditions
- Anorexia, Thalassemia, Sickle Cell Anemia, Chronic Renal Failure
- Trial name
- NCT00735540
- Testing
- Observational
- Where
- Israel
- Volunteers
- 1,389 people
- Sponsor
- HaEmek Medical Center, Israel
Anemia, Puerperal Disorders
Intravenous Iron Versus Oral Iron for Severe Postpartum Anemia
The aim of the study is to compare the effect of intravenous versus oral iron in women with severe postpartum anemia.
- Trial name
- NCT00660933
- Testing
- Iron sucrose, NaCl
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Clinic of Barcelona
Anemia, Chronic Kidney Diseases
Effect of rEPO in FGF23 in ESRD Patients
Objective: To evaluate the effects of recombinant Erythropoietin (rEPO) in plasma levels of Fibroblast Growth Factor 23 (FGF23) in End-Stage Renal Disease (ESRD) patients in hemodialysis.
- Trial name
- NCT03803514
- Testing
- Recombinant EPO
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Anaemia, Renal Transplantation
Correction of Anaemia and Progression of Renal Failure on Transplanted Patients
The purpose of this study is to evaluate, on renal transplanted patients with CGD, the effect of two levels of haemoglobin on quality of life at 6 months and the speed of progression of renal function degradation at 24 months.
- Conditions
- Anaemia, Renal Transplantation, Kidney Failure
- Trial name
- NCT00396435
- Testing
- Neorecormon
- Where
- 20 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diabetes Mellitus, Chronic Kidney Disease
A Proof-of-Concept Study of Darbepoetin Alfa in Partial Correction of Anemia in Chinese With Diabetic Nephropathy
The purpose of this study is to examine the effect of partial correction of anemia with Darbepoetin alfa to a target of 11 g.dL (female) or 12 g/dL (male) on the reduction of cardiovascular morbidity and total mortality.
- Conditions
- Diabetes Mellitus, Chronic Kidney Disease, Anemia
- Trial name
- NCT00907608
- Testing
- Darbepoetin alfa
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Chronic Renal Failure Requiring Hemodialysis
A Phase 3, Long-Term Safety Study of Intravenous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of the study is to determine the long-term safety in treatment-emergent adverse events (TEAEs) of intravenous (IV) administration of Epoetin Hospira for maintenance of target hemoglobin (Hgb) levels in patients…
- Trial name
- AiME - 03 (NCT01628107)
- Testing
- Epoetin Hospira
- Where
- 110 sites in United States, Puerto Rico
- Volunteers
- 406 people
- Sponsor
- Pfizer
Anemia Complicating Pregnancy
Pharmacist Led Intervention in the Management of Anemia Among Pregnant Woman
Anemia is a major public health problem among pregnant women, particularly in low- and middle-income countries. It is characterized by a reduction in hemoglobin concentration or the oxygen-carrying capacity of the blood, which…
- Trial name
- HB Ph (NCT07800611)
- Testing
- Pharmacist-led counseling on anemia management
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Hamdard University
Pure Red-Cell Aplasia, Chronic Kidney Failure
Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure
The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) epoetin alfa (polysorbate…
- Trial name
- PRIMS (NCT00391287)
- Where
- 387 sites in Australia, Belgium and 13 more
- Volunteers
- 15,334 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Twin to Twin Transfusion Syndrome, Pregnancy Complications
Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.
The ZTWINS registry study is an observational, prospective, multi-center study observing women carrying a twin pregnancy who receive snp-based non-invasive prenatal screening and zygosity assessment as part of their medical care.
- Conditions
- Twin to Twin Transfusion Syndrome, Pregnancy Complications, Multiple Gestation; Maternal Care
- Trial name
- ZTWINS (NCT05312814)
- Where
- 8 sites in United States
- Volunteers
- 137 people
- Sponsor
- Natera, Inc.
Atypical Hemolytic Uremic Syndrome
A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of Cemdisiran in patients with aHUS.
- Trial name
- NCT03303313
- Testing
- Cemdisiran
- Where
- 12 sites in Bosnia and Herzegovina, Canada and 8 more
- Sponsor
- Alnylam Pharmaceuticals
Kidney Disease, Chronic Kidney Disease
Study Evaluating Darbepoetin Alfa in Subjects With Chronic Kidney Disease (CKD) Receiving Dialysis
The proposed study is designed to test a novel dosing paradigm that would facilitate the treatment of anemia in CKD patients on dialysis.
- Trial name
- NCT00096915
- Testing
- Darbepoetin Alfa
- Volunteers
- 110 people
- Sponsor
- Amgen
Iron Deficiency Anaemia
Questionnaire About Risk Factors of Iron Deficiency Anemia in Pregnancy
Anemia in pregnancy,and especially iron deficiency anemia is both a long standing scholarly interest ,the aim of my research to summarise the risk factors of iron deficiency anemia in pregnancy, especially in Egypt as a less…
- Trial name
- NCT06761352
- Volunteers
- 200 people
- Sponsor
- Assiut University
Anemia, Chronic Kidney Disease Stage 5
The Effect of Fermented Papaya Preparation on Patients With Chronic Kidney Disease Under Dialysis Receiving Intravenous Iron
Fermented papaya preparation has been reported to bind and neutralize reactive oxygen species as well as iron. Patients undergoing hemodialysis are generally on iron overload status due to their inability to use iron storage…
- Trial name
- NCT03005847
- Testing
- fermented papaya preparation
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Iron Deficiency Anemia of Pregnancy
Lactoferrin Versus Ferrous Sulphate for the Treatment of Iron Deficiency Anemia During Pregnancy
The study aims to compare the efficacy and the safety of Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy.
- Trial name
- Lactoferrin (NCT03456258)
- Testing
- Complete blood count
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypothermia, Anemia
Delayed Cord Clamping in Premature Infants
Delayed cord clamping has been shown to decrease the risk of bleeding in the brain of premature infants. However this procedure is not standard due to concerns that the premature infant will get too cold.
- Trial name
- NCT01018576
- Testing
- Delayed cord clamping
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Davis
Iron Deficiency Anemia of Pregnancy
Efficacy of Iron Bisglycinate in Treatment of Iron Deficiency Anemia in Pregnant Women
Anemia in pregnancy is defined by the World Health Organization as hemoglobin levels of ≤ 11 g/dl. Globally, a prevalence rate of 38% was estimated by the World Health Organization for pregnant women.Treatment of iron deficiency…
- Trial name
- NCT03378791
- Testing
- Iron bisglycinate Oral Tablet, Ferrous Fumarate Oral Tablet
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Hatem AbuHashim
Sickle Cell Disease, Chronic Kidney Diseases
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
The purpose of this study is to test the efficacy of a peer support coaching intervention to improve activated chronic illness self-management versus an attention control group in 225 adolescents and young adults with childhood…
- Conditions
- Sickle Cell Disease, Chronic Kidney Diseases, Systemic Lupus Erythematosus, Childhood Cancer
- Trial name
- PiCASO (NCT03938324)
- Testing
- PiCASO Intervention Group
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Duke University
Pure Red-cell Aplasia
A Study of Risk Factors for Anti-erythropoietin Antibody Positive Pure Red Cell Aplasia Among Patients With Chronic Kidney Disease Receiving Epoetin Alfa
The purpose of this study is to collect historical occurrences of risk factors that are potentially associated with the development of anti-erythropoietin (EPO) antibody positive pure red cell aplasia (PRCA) in participants with…
- Trial name
- NCT00211068
- Testing
- No intervention
- Where
- 22 sites in Brazil, France and 5 more
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Atypical Hemolytic Uremic Syndrome
Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)
The purpose of this study is to determine whether eculizumab is safe and effective in the treatment of adult patients with plasma therapy-sensitive Atypical Hemolytic-Uremic Syndrome (aHUS).
- Trial name
- aHUS (NCT00838513)
- Testing
- eculizumab
- Where
- 13 sites in Canada, France and 5 more
- Volunteers
- 15 people
- Sponsor
- Alexion Pharmaceuticals, Inc.