Clinical trials: Pregnancy Detection
Congenital Heart Defect, Heart Defects, Congenital
Fetal Cardiac Anomalies at Anomaly Scan: Detection and Pregnancy Outcomes - Assiut 2026
Congenital heart defects are among the most common congenital anomalies and cause significant perinatal morbidity and mortality. Prenatal detection allows counseling, multidisciplinary planning and optimization of delivery.
- Trial name
- NCT07832851
- Volunteers
- 200 people
- Sponsor
- Assiut University
Pregnancy
Testing a Wearable Monitor for Fetal Heart Rate Estimation, Fetal Movement and Uterine Activity Detection
Owlet Baby Care, Inc. has developed a wearable fabric band pregnancy monitor, to be worn around the maternal abdomen incorporating electrocardiogram sensors.
- Trial name
- NCT04450251
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Owlet Baby Care, Inc.
Oxytocin, Pregnancy
Non-Invasive, Highly Specific Detection of Oxytocin in Biological Fluids
This study will aid in the development of a research instrument for rapid and highly sensitive detection of perinatal salivary oxytocin, by non-invasive means.
- Trial name
- NCT03140709
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Delivery
The Effectiveness of a Care Bundle to Prevent Postpartum Hemorrhage After Cesarean Delivery
Delays in the detection or inconsistent use of effective interventions of postpartum hemorrhage can result in complications or death.
- Trial name
- RE-TEAM (NCT06684080)
- Testing
- A care bundle
- Volunteers
- 52,000 people
- Sponsor
- Dunjin Chen
Fetal Malformation, Pregnancy Related
Realization of Sequencing of All Known Human Genes in Case of Detection of Cerebral, Renal or Ophthalmological Fetal Malformations During Pregnancy in Order to Make an Etiological Diagnosis and to Precise the Fetal Prognosis
Congenital malformations concern 3% of pregnancies; most of them can be seen during pregnancy. For some malformations, an invasive sample (trophoblast biopsy or amniocentesis) is proposed to search a chromosomal abnormality by…
- Conditions
- Fetal Malformation, Pregnancy Related, Rare Genetic Disease
- Trial name
- PRENATEX (NCT04406480)
- Testing
- CGH-array and exome sequencing
- Where
- 12 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Strasbourg, France
Ectopic Pregnancy
Evaluation of the Axonemal Dynein Heavy Chain 5 and Creatine Kinase Concentration in Cervical Fluid for Early Detection of the Ectopic Pregnancy
Patients who have doubt for ectopic pregnancy will be enrolled for our study. These patients will be determined with using irregular increased human chorionic gonadotropin (beta-HCG) results and no embryo reported ultrasonography…
- Trial name
- NCT02995356
- Testing
- Collecting cervical liquid and sera samples
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ege University
Large for Gestational Age (LGA), Pregnancy
Repeat Late GDM Testing and Cesarean Delivery Rates
The goal of this randomized trial is determine if re-testing for gestational diabetes in the third trimester after an ultrasound measurement of estimated fetal weight (EFW) or abdominal circumference greater than 90%ile decreases…
- Trial name
- NCT07708129
- Testing
- Glucose tolerance test and continuous glucose monitor
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shauna F. Williams, MD
Endometrial Cancer
Circulating Tumor DNA Study in Patients With Endometrial Cancer
The objective of this study is to identify a population at risk of early recurrence after oncologic resection surgery of a primary uterine tumor based on the detection of ctDNA
- Trial name
- ctDNA-endo (NCT05955079)
- Testing
- Whole blood
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometrial Cancer
Pelvic Sentinel Node Detection Using Indocyanine Green Learning Curve
According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri.
- Trial name
- ENDO-GREEN (NCT04958278)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Herpes Simplex, HIV Infections
The Effect of Valacyclovir on the Detection of HIV From Genital Herpes Lesions in HIV-Infected Patients
The purpose of this study is to see if valacyclovir affects the detection of HIV in genital herpes lesions in HIV-infected patients. Valacyclovir is used to treat recurrent genital herpes.
- Trial name
- NCT00002404
- Testing
- Valacyclovir hydrochloride
- Volunteers
- 30 people
- Sponsor
- Glaxo Wellcome
Lung Cancer, Gastric Cancer
INSPIRE: a Multi-Cancer Early Detection Study
This research constitutes a multi-centric, case-control designed investigation aimed at developing and implementing a blinded validation of a machine learning-powered, multi-cancer early detection model.
- Conditions
- Lung Cancer, Gastric Cancer, Liver Cancer, Colorectal Cancer
- Trial name
- INSPIRE (NCT06440018)
- Where
- China
- Volunteers
- 5,350 people
- Sponsor
- Singlera Genomics Inc.
Bladder Cancer
Mass Spectrometry in Single Bladder Cancer Cells
The study is a pilot study in the feasibility of a diagnostic technique. There is no current data on detection of cisplatin in cancer cells derived from human urine.
- Trial name
- NCT03639090
- Testing
- mass spectrometry
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Oklahoma
Atrial Fibrillation, Chronic Kidney Diseases
Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease
The aim of the Check@Home consortium is to set up a roadmap and infrastructure for a program to early detect atrial fibrillation and chronic kidney disease in the general population.
- Conditions
- Atrial Fibrillation, Chronic Kidney Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT06330480
- Testing
- Intervention group
- Where
- Netherlands
- Volunteers
- 320,000 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Folkert W. Asselbergs
Endometrial Adenocarcinoma, Endometrial Carcinoma
Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care
This clinical trial studies universal screening for deoxyribonucleic acid (DNA) mismatch repair deficiency in patients with endometrial cancer, mutations in the genes responsible for Lynch syndrome (inherited forms of endometrial…
- Conditions
- Endometrial Adenocarcinoma, Endometrial Carcinoma, Lynch Syndrome, Relatives
- Trial name
- OPTEC (NCT03460483)
- Testing
- Genetic Counseling, Genetic Testing, Laboratory Biomarker Analysis
- Where
- 9 sites in United States
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Placenta Accreta
Detection of Urinary Bladder Wall Involvement in Abnormally Invasive Placenta (AIP) by 3D Ultrasonography
In the last three decades , the raise in cesarean delivery rates has led to a massive increase in the incidence of the abnormally invasive placenta .Complete separation of the abnormally invasive placenta is very difficult and…
- Trial name
- NCT05813743
- Testing
- 3 dimensional ultrasound
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Cervical Cancer
Molecular Imaging for Detection of Cervical Intraepithelial Neoplasia
The hypothesis of this research project is that topical application of the anti-EGFR or anti-E6/E7 contrast agents followed by optical imaging will yield images that reflect spatial variations in expression that correlate with…
- Trial name
- NCT00511615
- Testing
- Loop Electrosurgical Excision Procedure (LEEP)
- Where
- 4 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Algorithm for Cervix Carcinoma Screening
Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus
Cervix carcinoma has been a serious, long-term issue in the Czech Republic. The cause of nearly all cervix carcinomas is human papilomavirus (HPV).
- Trial name
- LIBUSE (NCT05578833)
- Testing
- HPV DNA test with selective HPV 16/18 genotyping (cobas® 4800 HPV Test, Roche), p16 and Ki-67 biomarker detection in the form of dual cytological staining (CINtec Plus, Roche), standard conventional cytology PAP test
- Where
- Czechia
- Volunteers
- 2,426 people
- Sponsor
- AeskuLab Pathology Prague
Adnexal Mass, Germline BRCA1 Gene Mutation
Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection
The objective of this project is to validate a next-generation assay that utilizes both the protein biomarkers of our already established ovarian cancer risk assessment combined with a molecular profile in both germline and early…
- Conditions
- Adnexal Mass, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation, Hereditary Breast and Ovarian Cancer
- Trial name
- OVA360 (NCT04668521)
- Testing
- OVA360
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Aspira Women's Health
Group B Streptococcal Infection, Infection Due to ESBL Bacteria
Simplified GBS Screening and Prevalence of ESBL in Pregnant Women
1. At the University Hospital Basel, Switzerland, a simplified screening for group B streptococci (GBS) of vagina and perineum has been performed since several years.
- Trial name
- NCT02142933
- Testing
- vagino-perineal swab
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University Hospital, Basel, Switzerland