Clinical trials: Pregnancy Detection
Algorithm for Cervix Carcinoma Screening
Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus
Cervix carcinoma has been a serious, long-term issue in the Czech Republic. The cause of nearly all cervix carcinomas is human papilomavirus (HPV).
- Trial name
- LIBUSE (NCT05578833)
- Testing
- HPV DNA test with selective HPV 16/18 genotyping (cobas® 4800 HPV Test, Roche), p16 and Ki-67 biomarker detection in the form of dual cytological staining (CINtec Plus, Roche), standard conventional cytology PAP test
- Where
- Czechia
- Volunteers
- 2,426 people
- Sponsor
- AeskuLab Pathology Prague
Preterm, Assessment
GMA and Peri in Moderate-late Preterms
To analyze the relationship between the early diagnosis of cerebral palsy with the risk factors of this pathology in moderate and late premature infants
- Conditions
- Preterm, Assessment, Risk Factor, Cerebral Palsy
- Trial name
- NCT04073836
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Ovarian Cancer
Early Detection of Ovarian Cancer Using Plasma Cell-free DNA Fragmentomics (Retrospective Study)
The purpose of this study is to enable non-invasive early detection of ovarian cancer in high-risk populations through the establishment of a multimodal machine learning model using plasma cell-free DNA fragmentomics.
- Trial name
- NCT05693974
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Acute Kidney Injury, Kidney Injury
Automated urIne Flow Detection to Reduce Errors and Nursing Workload
This study is an observational study which seeks to examine a) the accuracy of the Clarity Renal Monitoring System (Clarity RMS)® sensor kit at the bedside compared to manual urine output monitoring, b) total time/effort per…
- Trial name
- AiDe-RN (NCT03636113)
- Testing
- Clarity RMS Electronic Sensor
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Hemolytic Disease of the Newborn
Application of Quantitative Hemorrhage Detection in Fetomaternal Hemorrhage Syndrome for the Diagnosis of Hemolytic Disease of the Newborn
This study adopted a single-center, prospective, observational study design. A consecutive cohort of pregnant and postpartum women who met the inclusion criteria was recruited from Shanghai First People's Hospital between January…
- Trial name
- NCT07371520
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Acute Renal Failure, Iatrogenic Effect
Detection of Acute Renal Failure Using Hospital Coding Data
AKI is a rapid and usually reversible impairment of kidney function that is life-threatening in the short term well described by the "Kidney Disease: Improving Global Outcomes - KDIGO" classification of 2012.
- Conditions
- Acute Renal Failure, Iatrogenic Effect, Uremic Toxin
- Trial name
- IRA-PMSI (NCT04923750)
- Where
- France
- Volunteers
- 498 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Compliance, Cervical Cancer
Patient Compliance to Self-collection for Detection of HPV-DNA
A study to investigate the compliance of unassisted women to self-collection of specimens for Hybrid Capture (HC) for detection of Human Papilloma Virus (HPV) DNA compared to Pap smear collection by medical personnel, as…
- Trial name
- NCT02431520
- Testing
- Self-collection, Gynecologist collection
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Oswaldo Cruz Foundation
Fetal Membranes, Premature Rupture
Early Detection of Chorioamnionitis in Preterm Premature Rupture of Membranes
All included patients will have their fetal heart rate recording performed with an EDAN F3 fetal monitor that allowed the back up recording of the fetal heart rate beat to beat detection.
- Trial name
- AiRPM (NCT02901795)
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Rennes University Hospital
Cervical Cancer
Use of SMSs to Improve Attendance to Cervical Cancer Follow-up Screening
This study evaluates the effect of the SMS intervention 'Connected2Care' on the attendance rate to cervical cancer screening follow-up appointments.
- Trial name
- NCT02509702
- Testing
- Connected to Care
- Where
- 3 sites in Tanzania
- Volunteers
- 705 people
- Sponsor
- Marianne Andersen
Cervical Cancer
Results Comparison of Cervical Cancer Early Detection Using Cerviray With VIA Test
Cervical cancer, primarily caused by Human Papilloma Virus (HPV), is a significant global health concern, ranking as the fourth most common cancer in women worldwide.
- Trial name
- NCT06518070
- Testing
- Cerviray AI
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Ovarian Cancer
Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women
The goal of this clinical research study is to find out if combining a standard blood test (CA-125) that checks for ovarian cancer with other blood tests that check for related tumor markers may be helpful in the early detection…
- Trial name
- NCT00539162
- Testing
- Questionnaire
- Where
- 12 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gynecologic Malignant Tumor
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
As human aging, 50% of women will be faced with the threat of cancer, especially gynecological malignancies. Ovarian, cervical and endometrial cancer are three major gynecological malignancies.
- Trial name
- NCT02166515
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiqing, Liang
Ovarian Cancer
Detection of Ovarian Cancer Using an Artificial Intelligence Enabled Transvaginal Ultrasound Imaging Algorithm
Ovarian cancer is relatively rare but fatal with an annual incidence rate of 11.8 per 100 000 and a high mortality-to-incidence ratio of >0.6.
- Trial name
- NCT04214782
- Testing
- Artificial Intelligence Enabled Transvaginal Ultrasound Imaging algorithm
- Volunteers
- 10,000 people
- Sponsor
- Tongji Hospital
Meconium
Detection of Meconium in Amniotic Fluid in Post Term Pregnancies
Meconium constitutes the bowel contents of the fetus and is normally expelled only after birth. However, it may be secreted into the amniotic fluid of 20% of all fetuses.
- Trial name
- NCT01429974
- Testing
- amniometer model po1
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- Sheba Medical Center
Neoplasm, Colorectal, Neoplasm, Breast
Development, Implementation and Evaluation of an Individual Decision Aid in Swedish Cancer Screening Programs
Background: Sweden has a long tradition of organized national population-based screening programs. Participation rates differ between programs and regions, are relatively high in some groups, but lower in other.
- Conditions
- Neoplasm, Colorectal, Neoplasm, Breast, Neoplasm, Ovarian
- Trial name
- BESTa (NCT05512260)
- Testing
- Individual decision aid (iDA)
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Advanced Non Small Cell Lung Cancer, Uterine Cancer
Clinical Study of PD-1 Monoclonal Antibody SHR-1210 and Apatinib in Advanced NSCLC, Soft Tissue Sarcoma, and Uterine Cancer
In this one-arm study, histologically or cytologically confirmed advanced NSCLC, uterine malignancies, and soft tissue sarcoma will be enrolled to investigate the efficacy and safety of PD-1 monoclonal antibody SHR-1210 and…
- Conditions
- Advanced Non Small Cell Lung Cancer, Uterine Cancer, Soft Tissue Sarcoma
- Trial name
- NCT04239443
- Testing
- PD-1 inhibitor, Apatinib
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hunan Cancer Hospital
Ovarian Neoplasms
Ovarium Cancer Detection by TEP's and ctDNA
Rationale: Cancer is primarily diagnosed by clinical presentation, imaging and pathological analysis of tissue biopsies, increasingly supported by molecular diagnostics tests.
- Trial name
- NCT04022863
- Testing
- TEP, ctDNA
- Where
- 3 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Early Detection of Cancer
The Effect of Face-to-face and Online Health Education on Women's Cervical Cancer Knowledge, Health Beliefs and Screening
Aim: The aim of this study is to determine the effect of health education given by two different methods on women's knowledge about HPV, cervical cancer health belief and screening test.
- Trial name
- NCT06021496
- Testing
- face to face health education, online health education
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Endometrial Neoplasms
Indocyanine Green Versus Blue Dye for Detection of Sentinel Lymph Node In Endometrial Cancer
To determine the difference in the proportion of hemipelves with successful detection of Sentinel Lymph Node according to the dye used (indocyanine green with near-infrared imaging vs blue dye) in women with endometrial cancer.
- Trial name
- NCT02564276
- Testing
- Sentinel lymph node biopsy
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)