Clinical trials: Pregnancy Detection
Ovarian Cancer
CADx - Radiomics to Distinguish the Origin of Ovarian Tumors
In women with an ovarian tumor, it is often unclear whether the tumor is benign or malignant. To differentiate, tumor markers (CA125 and CEA), a transvaginal ultrasound and, depending on the ultrasound image and the CA125…
- Trial name
- CADx (NCT05174377)
- Testing
- CT-scan algorithm
- Where
- 5 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Dengue
Combating Dengue With Innovative, Paradigm-shift-Strategies: Early Dengue Surveillance in Adult Aedes Mosquitoes
During dengue outbreaks, the Ministry of Health Malaysia employs various methods to control the spread of disease, including killing the larvae of Aedes mosquitoes, fogging, together with educating and disseminating information…
- Trial name
- NCT03799237
- Testing
- GOS trap and dengue NS1 antigen kit
- Where
- Malaysia
- Volunteers
- 7,979 people, healthy volunteers welcome
- Sponsor
- Jonathan Liew Wee Kent
Pregnancy Preterm
Evaluation of Vaginal PAMG-1 Detection by PartoSure Test in Preterm Delivery Threat in Actual Clinical Situation: Randomized Controlled Trial
Prematurity is defined as birth before 37 weeks of amenorrhea. It is the leading cause of perinatal morbidity and mortality. It is estimated that premature births to 15 million worldwide in 2010, including 60,000 children in…
- Trial name
- PARTO-MAP (NCT03675061)
- Testing
- Current care, PartoSure Test negative, PartoSure Test positive
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Brest
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Pregnancy
Accuracy of Whole-Blood Testing for Rapid Detection of Pregnancy
It is common practice in the emergency medicine department to rapidly assess pregnancy status through the use of either urine or serum in pregnancy tests.
- Trial name
- NCT00373139
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Ovarian Cancer
Determination of the Feasibility of Tumoural Somatic Mutations Detection in Blood of Patients With Ovarian Cancer
BOVARY-Pilot is a monocentric prospective transversal pilot study with a total duration of 6 months. The purpose of this study is to determine the feasibility of detecting somatic tumor mutations in the blood of patients with…
- Trial name
- BOVARY Pilot (NCT03881683)
- Testing
- HRD and BRCA mutations
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Institut de Cancérologie de Lorraine
Anovulation, Hyperandrogenism
Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome
Background: Infertility affects up to 15% of married couples. About half are attributable to female factors, among which anovulation is the leading cause.
- Conditions
- Anovulation, Hyperandrogenism, Polycystic Ovary Syndrome, Single Nucleotide Polymorphism
- Trial name
- NCT00665171
- Where
- Israel
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Maaynei Hayesha Medical Center
Fetal Hypoxia, Fetal Monitoring
Evaluation of the Fetal Response to Intrapartum Digital Fetal Scalp Stimulation to Identify Intrapartum Fetal Hypoxia.
The main objective of this study is to evaluate whether digital fetal scalp stimulation improves fetal well-being in fetuses with suspicious or pathological cardiotocographic recordings, showing an improvement in…
- Trial name
- NCT07035028
- Testing
- Digital fetal scalp stimulation dFSS
- Where
- 2 sites in Spain
- Volunteers
- 182 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Nephrogenic Systemic Fibrosis, Renal Insufficiency
Evaluation of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Following OptiMARK Injection
The objective of this study is to prospectively monitor the incidence of adverse drug reactions, specifically NSF during routine use of gadoversetamide in a large number of patients with moderate renal insufficiency (eGFR 30-59)…
- Trial name
- SHERLOC (NCT00811863)
- Where
- United States
- Sponsor
- Guerbet
Bladder Cancer
The Cxbladder Rule-out of Recurrent Urothelial Carcinoma
This observational study is designed to collect urine and relevant clinical information from patients who have a known diagnosis of bladder cancer and currently on clinically driven surveillance.
- Trial name
- NCT03673202
- Testing
- Cx bladder Monitor test
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre
Acute Kidney Injury
Neutrophil Gelatinase-associated Lipocalin in Major Abdominal Surgery
Acute kidney injury (AKI) after major surgery is a well-known complication. The incidence of AKI after major surgery ranges from 13% to 50%.
- Trial name
- NCT05721638
- Testing
- Neutrophil gelatinase-associated lipocalin
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Antalya Training and Research Hospital
Pre-Eclampsia
Detection of False Positives From First-trimester Preeclampsia Screening (StopPRE) at the Second-trimester of Pregnancy
Pregnant women at a higher risk for pre-eclampsia (PE) should be offered preventive daily treatment with acetylsalicylic acid (ASA) started before 16 weeks of gestation.
- Trial name
- StopPRE (NCT03741179)
- Testing
- ASA-withdrawn group
- Where
- Spain
- Volunteers
- 974 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Endometrial Disease
Intrauterine Saline Washing for Detection Endometrial Disease in Patients With Abnormal Uterine Bleeding
Investigator will examined the diagnostic effect of the endometrial washing by saline. Because this technique more less painful and easier compared to endometrial curettage. Participants will separate into two groups.
- Trial name
- NCT02691715
- Testing
- Endometrial saline plus curettage, Endometrial curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Epithelial Ovarian Cancer
Exploration of DNA Methylation as a Marker for Early Detection of High Grade Serous Epithelial Ovarian Cancer
The purpose of this study is to determine if there are markers in plasma that can be used to develop a diagnostic panel for early detection and diagnosis of high grade serous epithelial ovarian cancer.
- Trial name
- NCT03622385
- Testing
- DNA Methylation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Bladder Cancer
Bladder Cancer Detection Using Convolutional Neural Networks
The investigators aim to experiment and implement various deep learning architectures to achieve human-level accuracy in Computer-aided diagnosis (CAD) systems.
- Trial name
- BLAInostic (NCT05193656)
- Testing
- Al_bladder
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- Zealand University Hospital
Endometrial Cancer, Cervical Cancer
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human…
- Conditions
- Endometrial Cancer, Cervical Cancer, Atypical Endometrial Hyperplasia, Cervical Dysplasia
- Trial name
- ECHO (NCT05051722)
- Testing
- Vaginal Fluid Collection, Blood Collection
- Where
- 25 sites in United States
- Volunteers
- 3,110 people
- Sponsor
- Mayo Clinic
Preterm Labor, Immunochromatographic Assay
Diagnostic Tests in the Context of Threatened Preterm Labour
The primary purpose of the protocol is to compare the diagnostic accuracy in terms of positive and negative predictive values of Premaquick © (combined detection of IL-6 / IGFBP-1 total / IGFBP-1 native) and Quikcheck fFN ™…
- Conditions
- Preterm Labor, Immunochromatographic Assay, Predictive Value of Tests, Preterm Delivery
- Trial name
- PREMAQUICK (NCT03608995)
- Testing
- Premaquick (Diagnostic test), Quikcheck fFN ™
- Where
- France
- Volunteers
- 221 people
- Sponsor
- University Hospital, Clermont-Ferrand
Vulvar Cancer
Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer
The purpose of this study is to compare two types of imaging for sentinel lymph node (SLN) mapping in people with early-stage vulvar cancer.
- Trial name
- NCT06127836
- Testing
- ICG guided sentinel lymph node biopsy
- Where
- 8 sites in United States
- Volunteers
- 22 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postpartum Depression, Postpartum Anxiety
Virtual Group Psychoeducational Discussions With Spanish-Speaking Mothers of Infants in Pediatric Primary Care
The goal of the proposed research is to test the feasibility and acceptability of a virtual group session which is intended to be offered universally to Spanish-speaking parents of newborns/infants attending pediatric primary…
- Trial name
- NCT05423093
- Testing
- Single-Session Virtual Group Psychoeducational Session about Postpartum Depression
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University