Clinical trials: Pregnancy Detection
Lung Cancer, Gastric Cancer
INSPIRE: a Multi-Cancer Early Detection Study
This research constitutes a multi-centric, case-control designed investigation aimed at developing and implementing a blinded validation of a machine learning-powered, multi-cancer early detection model.
- Conditions
- Lung Cancer, Gastric Cancer, Liver Cancer, Colorectal Cancer
- Trial name
- INSPIRE (NCT06440018)
- Where
- China
- Volunteers
- 5,350 people
- Sponsor
- Singlera Genomics Inc.
Breast Cancer, Cervical Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 2
The purpose of this study is to increase early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and cervical cancer screening and Human Papillomavirus (HPV)…
- Trial name
- SEMM2 (NCT06082882)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pregnancy; Death of Fetus, Early Pregnancy, Uremia in Pregnancy Without Hypertension
Detection and Identification of Preeclampsia Via Volatile Biomarkers
Preeclampsia is a form of hypertension that is unique to human pregnancy. The incidence of the disease ranges between 2 and 7 percent in healthy nulliparous women. The etiology of preeclampsia is unknown.
- Trial name
- DIP (NCT01291342)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Nazareth Hospital, Israel
Fetal Growth Retardation
Placental Lesions in Fetal Growth Restrictions
The purpose of this research study is to develop imaging methods to diagnose placental injury in pregnancies diagnosed with fetal growth restriction (FGR).
- Trial name
- NCT04839185
- Testing
- Ferumoxytol infusion, MRI scan
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Wisconsin, Madison
Nephrotic Syndrome With Edema (Diagnosis), Minimal Change Nephrotic Syndrome
SLIT ABS: Study on Patients With Autoimmune Podocytopathy
Nephrotic syndrome is a kidney condition that mainly affects children and is characterized by high levels of protein in the urine, low levels of protein in the blood, and swelling.
- Conditions
- Nephrotic Syndrome With Edema (Diagnosis), Minimal Change Nephrotic Syndrome, Focal Segmental Glomerulosclerosis (FSGS), Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy
- Trial name
- NCT07516964
- Testing
- Serum and renal tissue analysis
- Where
- 14 sites in United States, Germany and 3 more
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
Ovarian Cancer, Ovarian Carcinoma
Biomarkers for Early Detection of Ovarian Cancer Using Uterine Lavage
Screening programs for high-grade ovarian carcinoma failed to reduce disease-specific mortality, since they do not offer early enough detection of the disease.
- Conditions
- Ovarian Cancer, Ovarian Carcinoma, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
- Trial name
- BEDOCA (NCT03150121)
- Testing
- Uterine lavage, Blood sample, Uterine lavage catheter
- Where
- 4 sites in Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Endometrial Neoplasms, DNA Methylation
Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up
The goal of this observational study is to evaluate the accuracy of a novel molecular test for screening and monitoring endometrial lesions in women at medium-to-high risk for endometrial cancer.
- Conditions
- Endometrial Neoplasms, DNA Methylation, Cervical Smears, Early Detection of Cancer
- Trial name
- EndoMethy-V (NCT07298707)
- Volunteers
- 3,500 people
- Sponsor
- Peking Union Medical College Hospital
Cervical Cancer
Biop System's Safety and Performance
Biop system's safety and performance in increased detection of High-Grade lesions of the cervical epithelium in women scheduled for colposcopy
- Trial name
- NCT04232865
- Testing
- Biop System
- Volunteers
- 320 people
- Sponsor
- BIOP Medical
Metastatic Cancer Lung, Metastatic Ovarian Cancer
[18F]-AZAFOL AS POSITRON EMISSION TOMOGRAPHY (PET) TRACER in FR Positive Cancer Imaging
This is a clinical trial category C as this is a first in man trial with an unapproved investigational product. Nevertheless the risk is considered low due to the low dose ≤ 10μg.
- Trial name
- NCT03242993
- Testing
- [18F]-AzaFol, folarell
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Lausanne Hospitals
Pregnancy, Fertility
Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome
PIF: biomarker of successful implantation To overcome the poor reproductive potential of embryos generated during in vitro fertilization cycles and the lack of markers enabling the identification of the most competent ones, it is…
- Trial name
- PIF-SET1 (NCT01803893)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Cytomegalovirus Infections, Breast Feeding
Biochip for HCMV Detection in Breast Milk
Human cytomegalovirus (HCMV) is the leading cause of neonatal viral infection and can have a significant impact on the neurosensory development of newborns and especially preterm infants.
- Conditions
- Cytomegalovirus Infections, Breast Feeding, Premature Birth of Newborn
- Trial name
- VIRUMILK (NCT02840825)
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Fetal Cord Entanglement
Nuchal Cord Detection in Sonographic Evaluation by a First Year Resident.
The investigators aim to prove that minimal sonographic training for nuchal cord detection in an unexperienced first year medical resident is more than enough to detect the phenomenon.
- Trial name
- NCT03100929
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Congenital Anomaly
Examination of Pregnant Women in Third Trimester by Ultrasound to Detect Any Congenital Anomalies
this study aims to help the physicians to evaluate the practice of routine Third trimestric fetal scan whether it should be routinely performed to all cases including those with low risk singleton pregnancies.
- Trial name
- NCT06628063
- Testing
- ultrasound evaluation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diabetic Nephropathies
Doppler Ultrasound in Early Detection of Diabetic Nephropathy Type 2 Diabetes Mellitus.
Doppler sonography provides an easily applicable, non-invasive, and well-established method for investigating renal morphologic characteristics and measuring vascular resistance in the renal parenchyma.
- Trial name
- NCT03284996
- Testing
- Doppler ultrasonography
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cervical Cancer, LSIL
oncoFISH Cervical Test for Detection of 3q26 Region Gain
The purpose of this study is to evaluate the use of the oncoFISH cervical test system in the management of women who have received an LSIL Pap report to determine whether the test can predict which women will progress to more…
- Trial name
- NCT01416922
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Ikonisys, Inc.
Pancreas Cancer
Precision Imaging for Early Detection and Targeted Treatment Monitoring in Pancreatic Cancer
Specifically, in this project, the objective will be developped a model to capture imaging-based tumor heterogeneity with multiscale radiomics approach by obtaining the mirror tumor image at in vivo MRI, ex vivo MRI at histology.
- Trial name
- PANC-O-MICS (NCT06144762)
- Testing
- Biological/Vaccine: Blood sample and tissue sample
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Hereditary Cancer Syndrome
CfDNA in Hereditary And High-risk Malignancies 2
The goal of this study is to understand the performance of an experimental blood test that aims to detect early tumors in patients with hereditary cancer syndromes.
- Trial name
- CHARM2 (NCT06726642)
- Testing
- Cell-free DNA analysis
- Where
- 8 sites in Canada
- Volunteers
- 1,000 people
- Sponsor
- University Health Network, Toronto
Healthy Subject, Metastatic Renal Cell Cancer
Myeloid Derived Suppressor Cells Clinical Assay in Finding Kidney Cancer
This pilot research trial studies the use of the Myeloid Derived Suppressor Cells Clinical Assay in finding and monitoring kidney cancer.
- Conditions
- Healthy Subject, Metastatic Renal Cell Cancer, Recurrent Renal Cell Carcinoma, Stage I Renal Cell Cancer
- Trial name
- NCT02664883
- Testing
- Computed Tomography, Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Endometrial Cancer
Lymph Node Counts in Endometrial Cancer Staging
The purposes of this study are to determine whether total lymph node count or the percentage of identified nodes with metastatic disease are influenced by (1) the method of categorizing tissue specimens or (2) the techniques of…
- Trial name
- NCT02335775
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Duke University
Cervical Cancers, HPV Testing
Third-Generation Nanopore HPV Integration Site for Precise Prediction of Cervical Cancer Prognosis
Cervical cancer is a significant health threat to women, with over 500,000 new cases and approximately 342,000 deaths worldwide annually, and about 107,000 new cases in China with 51,000 fatalities.
- Conditions
- Cervical Cancers, HPV Testing, Nanopore Sequencing, HPV Integration Site Detection
- Trial name
- NCT06644677
- Testing
- HPV integration
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital