Clinical trials: Pregnancy Detection
Cervical Cancer
Mobile High-Resolution Microendoscopy (mHRME) for the Detection of Cervical Dysplasia in El Salvador
Evaluate the performance of the mHRME in a study of 3,000 women in San Salvador to assess whether mHRME imaging improves specificity of screening by VIA or HPV DNA without reducing sensitivity for cervical precancer and cancer.
- Trial name
- NCT04472455
- Testing
- HRME
- Volunteers
- 1,827 people, healthy volunteers welcome
- Sponsor
- William Marsh Rice University
Bone Metastases, Urogenital Cancer
Two Bed SPECT/CT Versus Planar Bone Scintigraphy in Detection of Osseous Metastases in Patients With Genitourinary Malignancies
The study aims to compare the diagnostic performance of planar bone scan and two bed SPECT/CT in detection of bone metastases in patients with urogenital cancer.
- Trial name
- NCT05597215
- Testing
- Tc-99m MDP and gamma camera
- Volunteers
- 70 people
- Sponsor
- Assiut University
Acute Kidney Injury
Real-time Early Detection of Nephrotoxicity by Urinary Biomarker Analysis With SeroFlow Technology
The study aims to perform real-time validation of the RenaFAST kit (a point-of-care test kit that quantifies three urinary proteins) in predicting acute kidney injury(AKI) among patients prescribed drug therapies of nephrotoxic…
- Trial name
- RenaFAST (NCT06124885)
- Testing
- AKI risk screening using RenaFAST POCT test kits
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
Urinary Bladder Neoplasms
GreenBladder - Early Detection of Bladder Cancer in Residents in Greenland Using a Urinary Marker and a Mobile Cystoscopy Unit
The goal of this observational study is to evaluate whether a urinary biomarker (Xpert® Bladder Cancer Detection Test) can be used as a selection tool to decide which patients that should undergo cystoscopy in haematuria work-up…
- Trial name
- NCT06281691
- Testing
- Xpert® Bladder Cancer Detection Test
- Where
- 2 sites in Denmark, Greenland
- Volunteers
- 127 people
- Sponsor
- Jørgen Bjerggaard Jensen
Endometrial Cancer
Biomarkers for Diagnosis and Prognosis of Endometrial Carcinoma
Endometrial cancer (EC) is the most frequent gynecological malignancy but there is currently lack of both non-invasive diagnostic tools and novel markers to stratify patients based on their risk of future recurrence.
- Trial name
- BioEndoCar (NCT03553589)
- Testing
- Blood sampling
- Where
- 5 sites in Netherlands, Poland and 1 more
- Volunteers
- 400 people
- Sponsor
- Andrea Romano
Ovarian Cancer, Endometrial Cancer
Advanced Methods for Cancer Detection by Vaginal Screening
This pilot study is the first step in the development of an new assay that may be further tested as a screening method for ovarian and endometrial cancers.
- Trial name
- ADVISE (NCT02622776)
- Testing
- Vaginal DNA Collection
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Anna Tinker
Bladder Cancer, Urine Marking
Genomic Imprinting Testing for Diagnosis of Bladder Cancer
Urine analysis provide a promising non-invasive liquid biopsy for diagnosis of bladder cancer. Molecular biomarkers in urine may serve as important diagnostic and prognostic indicators for bladder cancer.
- Conditions
- Bladder Cancer, Urine Marking, Diagnoses Disease
- Trial name
- NCT03563443
- Testing
- Genomic Imprinting Testing
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Atypical Squamous Cell of Undetermined Significance, ASC-US
Comparison Of Cytology And Molecular Screening For Detecting Cervical Reactive Cellular Changes In General Population
This study compares the efficacy of cytology (Pap smear) with the molecular screening in their ability to detect reactive cellular changes in the cervix among an open population
- Conditions
- Atypical Squamous Cell of Undetermined Significance, ASC-US, Atypical Glandular Cells of Uncertain Significance, AGUS
- Trial name
- NCT07211204
- Testing
- Physical examination, Liquid-based cytology, Molecular screening
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Timser SAPI de CV
Preeclampsia
Detection of Epileptiform Activity in Severe Preeclampsia
The primary aim of this pilot study is to prospectively quantify epileptiform activity in a cohort of preeclamptic patients before and after intravenous magnesium administration.
- Trial name
- NCT03494517
- Testing
- Magnesium Sulfate
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- Pascal Vuilleumier
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Bladder Cancer, Biomarker
Urine-DNA Biomarkers in Detecting Bladder Cancer
DNA biomarkers in urine are important diagnostic and prognostic indicators for bladder cancer. Many genetic alterations have been identified in the urinary DNA.
- Conditions
- Bladder Cancer, Biomarker, Diagnosis, Urine
- Trial name
- NCT03066310
- Testing
- Next generation sequencing
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Xiangya Hospital of Central South University
Preeclampsia (PE)
Validation of the MaiRa Preeclampsia Test for Screening Early/Late Preeclampsia in First and Second Trimesters
Preeclampsia (PE) is a major obstetric complication with severe short- and long-term consequences for both mother and fetus. Early detection is critical to mitigate PE-related morbidity and mortality.
- Trial name
- iPregnostic (NCT06716242)
- Testing
- Peripheral blood collection
- Where
- 11 sites in Spain
- Volunteers
- 7,473 people
- Sponsor
- iPremom
Gestational Diabetes Mellitus in Pregnancy
Improve Detection and Management of Gestational Diabetes Through the Primary Health Care Level in Morocco
A situational analysis on gestational diabetes conducted in 2015 in two districts in Morocco revealed difficulties in accessing screening for gestational diabetes (GDM) and delays in receiving appropriate care.
- Trial name
- NCT02979756
- Testing
- Decentralized GDM screening and initial management
- Where
- Morocco
- Volunteers
- 215 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Nephrotic Syndrome
Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome
The use of the renal resistive index in pediatric patient with idiopathic nephrotic syndrome to detect steroid resistance and to use it as a prognostic instrument of the progression of the disease.
- Trial name
- NCT05912673
- Testing
- renal doppler
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University