Clinical trials: Pregnancy Detection
Chronic Kidney Disease(CKD), Multimorbidity
Acceptability and Feasibility of Interventions for Integrated Care of Chronic Kidney Disease With Other Long-term Health Conditions in Malawi: a Qualitative Study
The burden of chronic kidney disease (CKD) is rising globally, but disproportionately impacting on low- and middle-income countries (LMIC) including Malawi, which have the fewest resources to manage it.
- Conditions
- Chronic Kidney Disease(CKD), Multimorbidity, Long-term Health Conditions
- Trial name
- Impso (NCT06807567)
- Testing
- Receipt of healthcare for long-term conditions, Provision of healthcare, Policy making
- Where
- Malawi
- Volunteers
- 60 people
- Sponsor
- Liverpool School of Tropical Medicine
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Postpartum Preeclampsia
Postpartum Preeclampsia Early Detection and Treatment: Nepal Pilot Study
The goal of this study is to address the significant morbidity associated with preeclampsia diagnosed after delivery. All participants will undergo biomarker evaluation with soluble fms-like tyrosine kinase-1 and placental growth…
- Trial name
- PREDiCT-NPL (NCT07185204)
- Testing
- Early detection and management of postpartum preeclampsia bundle
- Where
- 2 sites in United States, Nepal
- Volunteers
- 60 people
- Sponsor
- Medical College of Wisconsin
Congenital Heart Defect, Heart Defects, Congenital
Fetal Cardiac Anomalies at Anomaly Scan: Detection and Pregnancy Outcomes - Assiut 2026
Congenital heart defects are among the most common congenital anomalies and cause significant perinatal morbidity and mortality. Prenatal detection allows counseling, multidisciplinary planning and optimization of delivery.
- Trial name
- NCT07832851
- Volunteers
- 200 people
- Sponsor
- Assiut University
Ovarian Neoplasms
DOvEE - Diagnosing Ovarian & Endometrial Cancer Early
This study hopes to improve early detection of ovarian and endometrial cancers. It will determine if women with bloating, abdominal distension, abdominal/pelvic pain, increased urinary frequency and/or early satiety, benefit from…
- Trial name
- DOvEE (NCT02296307)
- Testing
- Blood test: CA-125 biomarker, Second Test: Transvaginal Ultrasound, Follow-up phone call
- Where
- 8 sites in Canada
- Volunteers
- 13,600 people
- Sponsor
- McGill University
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Bladder Cancer
Validation of Endoscopic Bimodal Imager for the Bladder Cancer Detection
This study evaluates the therapeutic value of: (i) simultaneous endoscopic visualization of the inner bladder using white light and blue light excitations and (ii) high resolution panoramic images of the bladder inner wall.
- Trial name
- CyPaM2 (NCT02800473)
- Testing
- Strorz (commercial), CyPaM2 (experimental)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut de Cancérologie de Lorraine
Brain Cancer, Breast Cancer
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types.
- Conditions
- Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer
- Trial name
- CAMPERR (NCT05366881)
- Where
- 17 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Adela, Inc
Motor Delay, Premature Birth
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Study Aims Pilot study: Due to the large recruitment goal and length of the project, the study team/PIs will evaluate the first cohort of 6-10 participants to refine study procedures and study-related materials.
- Conditions
- Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy
- Trial name
- NCT05568264
- Testing
- Physical Therapy intervention
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Shirley Ryan AbilityLab
Cervical Cancer
A Non-inferiority Evaluation of a Smart-phone Based Cervical Imaging Device.
When a woman has an abnormal pap smear or tests positive for a high risk strain of the HPV virus, the current standard of care includes culposcopic examination of the cervix with biopsy.
- Trial name
- NCT05388162
- Testing
- Mobile colposcope
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Cervical Cancer
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment
The purpose of this study is to determine if ctHPVDNA (circulating tumor HPV DNA) can be used as a non-invasive biomarker for identification and treatment monitoring of cervical cancer by characterizing correlation between plasma…
- Trial name
- NCT04743674
- Where
- 2 sites in United States, Malawi
- Volunteers
- 30 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Pregnancy, Pregnancy Complications
Detection of Risk Factors for Fetal Anomalies in a Rural Hospital Population
The purpose of the study is to estimate the rate of risk factors for appearance of disease or fetal malformations in a population who turn to hospital "Hillel Yaffe" and examine whether there is a difference in the rate of early…
- Trial name
- NCT01662596
- Where
- Israel
- Volunteers
- 320 people
- Sponsor
- Hillel Yaffe Medical Center
Diabetic Kidney Disease
Automatic Segmentation Ultrasound-based Radiomics Technology in Diabetic Kidney Disease
Diabetic kidney disease is a common complication of diabetes and the main cause of end-stage renal disease. In this study, the investigator plan to enroll nearly 500 participant with/without DKD and to develop an automatic…
- Trial name
- NCT05025540
- Testing
- ultrasonic imaging
- Where
- 3 sites in China
- Volunteers
- 499 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Infant, Premature, Diseases, Birth, Preterm
The NEU - CAP Trial
The aim of NEU-CAP is to investigate the clinical impact of using a colorimetric carbon dioxide (CO₂) detector during non-invasive ventilation (NIV). Infants born before 32 weeks of gestation will be included in this trial.
- Conditions
- Infant, Premature, Diseases, Birth, Preterm, Respiratory Distress Neonatal
- Trial name
- NEU-CAP (NCT07754032)
- Testing
- Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation
- Volunteers
- 1,860 people
- Sponsor
- Leiden University Medical Center
Cervical Cancer, Breast Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 1
The purpose is to evaluate implementation of a community-based prevention project aimed at increasing early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and…
- Trial name
- SEMM1 (NCT06082505)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,262 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Placenta Accreta
Detection of Urinary Bladder Wall Involvement in Abnormally Invasive Placenta (AIP) by 3D Ultrasonography
In the last three decades , the raise in cesarean delivery rates has led to a massive increase in the incidence of the abnormally invasive placenta .Complete separation of the abnormally invasive placenta is very difficult and…
- Trial name
- NCT05813743
- Testing
- 3 dimensional ultrasound
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Ovarian Diseases, Ovarian Neoplasms
Cancer Screening Program for Women at High Risk for Developing Ovarian Cancer
The main purpose of this program is to see whether periodically measuring CA-125 (tumor marker) levels in the blood and undergoing transvaginal ultrasounds over time will be effective in the early detection of ovarian cancer.
- Trial name
- OCEDP (NCT01292733)
- Testing
- Laboratory Tumor Marker Analysis, Transvaginal Ultrasound, Health Status Questionnaire
- Where
- United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Swedish Medical Center
Cervical Cancer, Cervix Neoplasm
Screening for Early Cervical Cancer Detection
This study is to audit results and adherence to Cervical Screening program before and after the implementing awareness of the WHO guidelines of screening among the multidisciplinary healthcare workers and patients.
- Trial name
- NCT06550583
- Testing
- Pap smear /Test
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cervical Cancer, Cervical Dysplasia
Self-sampling for Non-attenders to Cervical Cancer Screening
The trial will evaluate whether self-sampling and human papillomavirus (HPV) testing may increase cervical cancer screening attendance among under-screened women in Czech Republic.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- KOPRETINA (NCT04226313)
- Testing
- Self-sampling by Evalyn Brush, Self sampling by Evalyn Brush home or in GP´s clinic
- Where
- Czechia
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Pregnancy
Testing a Wearable Monitor for Fetal Heart Rate Estimation, Fetal Movement and Uterine Activity Detection
Owlet Baby Care, Inc. has developed a wearable fabric band pregnancy monitor, to be worn around the maternal abdomen incorporating electrocardiogram sensors.
- Trial name
- NCT04450251
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Owlet Baby Care, Inc.