Clinical trials: Pregnancy Hemorrhage
Obstetric Labor Complications, Hemorrhage
Coagulation Factor Changes Associated With Postpartum Hysterectomies
The purpose of this study is to examine components of the coagulation system in women undergoing postpartum hysterectomy and to compare laboratory parameters of coagulation in these women to women at increased risk for a…
- Conditions
- Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
- Trial name
- NCT00456547
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy; Fetomaternal Hemorrhage
Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.
This a open, prospective, multicenter, single-arm, phase III study for clinical assessment of anti-Rh immunoglobulin (KamRho-D®) in Rh and Coombs negative women with risk sensitization.
- Trial name
- NCT01666249
- Testing
- Immunoglobulin Anti-RhD
- Where
- 5 sites in Brazil
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
Heavy Menstrual Bleeding, Uterine Fibroids
Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The goal of this clinical trial is to determine the benefit of relugolix 40 milligrams (mg) once a day compared with placebo in heavy menstrual bleeding associated with uterine fibroids.
- Trial name
- NCT06671548
- Testing
- Relugolix
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Dysmenorrhea, Heavy Menstrual Bleeding
Heavy Menstrual Bleeding and Dysmenorrhea Among Undergraduate Females in the Faculty of Medicine of Assiut University
Menstrual disorders, particularly dysmenorrhea (painful menstruation) and heavy menstrual bleeding (excessive menstrual blood loss), are common conditions among young adult females that can substantially impact quality of life…
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Menorrhagia
- Trial name
- NCT07852143
- Volunteers
- 486 people
- Sponsor
- Assiut University
Postmenopausal Bleeding
Evaluation of DNA Methylation Markers for Endometrial Cancer Risk-stratification Using Patient-collected Urine and Vaginal Samples and Clinician-collected Cervical Samples From Women With Postmenopausal Bleeding
The goal of this observational study is to investigate the clinical utility of DNA-methylation testing in urine and vaginal samples collected by patients and cervical samples collected by clinicians, to determine the risk of…
- Trial name
- NCT07400835
- Testing
- DNA-methylation testing in patient-collected urine and vaginal samples and clinician-collected cervical samples
- Where
- 3 sites in Denmark
- Volunteers
- 600 people
- Sponsor
- University of Aarhus
Iron Deficiency Anemia, Heavy Menstrual Bleeding
Alternate Day Versus Daily Oral Iron Therapy in Adolescents
Iron deficiency anemia affects over half of girls and young women with heavy periods and is the most common cause of anemia worldwide.
- Conditions
- Iron Deficiency Anemia, Heavy Menstrual Bleeding, Abnormal Uterine Bleeding
- Trial name
- NCT05007899
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hematuria, Dysuria
Cystoscopy in Females: Is There a Difference Between Rigid and Flex Cystoscopy, and Does it Require Local Anasthesia?
Women arriving to the Urology department outpatient clinic at Assaf-Harofeh Medical Center in order to undergo a cystoscopy examination will be recruited.
- Conditions
- Hematuria, Dysuria, Recurrent Uti
- Trial name
- NCT03210038
- Testing
- Lidocaine, Water
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Assaf-Harofeh Medical Center
Idiopathic Menorrhagia
MiCo - Mirena or Conventional Medical Treatment for Menorrhagia
The aim of this prospective, non-interventional post-marketing surveillance study is to obtain data on safety and efficacy of Mirena in treatment of heavy menstrual bleeding (Menorrhagia) under daily-life treatment conditions.For…
- Trial name
- NCT01085487
- Testing
- Levonorgestrel (Mirena, BAY86-5028), Hormonal treatment, Antifibrinolytic treatment
- Where
- 14 sites in Albania, Bosnia and Herzegovina and 12 more
- Volunteers
- 1,211 people
- Sponsor
- Bayer
Dysfunctional Uterine Bleeding
Endometrial Ablation With Non-hysteroscopic Methods
Endometrial ablation in women with dysfunctional uterine bleeding using second generation ablation devices is a common widespread therapeutic approach.
- Trial name
- NCT01173965
- Testing
- MEA, Novasure
- Where
- 2 sites in Greece
- Volunteers
- 66 people
- Sponsor
- Aristotle University Of Thessaloniki
Contraceptive Usage
Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents
The specific aim of this study is to evaluate whether insertion of a long-acting contraceptive implant in postpartum adolescents prior to hospital discharge increases use of this highly effective contraception during the first…
- Trial name
- Implanon (NCT03585504)
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Mayer-Rokitansky-Kuster Syndrome, Asherson's Syndrome
INvestigational Study Into Transplantation of the Uterus
Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors
- Conditions
- Mayer-Rokitansky-Kuster Syndrome, Asherson's Syndrome, Postpartum Hemorrhage, Cervical Cancer
- Trial name
- INSITU (NCT04244409)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Womb Transplant UK
Postmenopausal Bleeding, Endometrial Cancer
Assessing the Benefit of Pipelle Biopsy in Patients With Postmenopausal Bleeding and an Atrophic-appearing Cavity
Postmenopausal bleeding (PMB) is the occurrence of vaginal bleeding 12 months following a woman's last menstrual cycle. PMB represents one of the most common reasons for referral to gynaecology services.
- Conditions
- Postmenopausal Bleeding, Endometrial Cancer, Endometrial Hyperplasia
- Trial name
- NCT05378152
- Testing
- Pipelle biopsy catheter
- Where
- Ireland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Abnormal Uterine Bleeding
Comparison of Manual Vacuum Aspiration and Dilatation and Curettage for Endometrial Sampling Adequacy in Women With Abnormal Uterine Bleeding
This randomized controlled trial was conducted in the Department of Obstetrics and Gynecology, Sheikh Zayed Hospital, Rahim Yar Khan, to compare two commonly used methods for obtaining endometrial tissue in women aged 30 to 60…
- Trial name
- NCT07349108
- Testing
- Manual Vacuum Aspiration, Dilatation and Curettage
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Sheikh Zayed Medical College
Preterm Birth
Preterm Infant Transport Stress (PremiTranS) Study
This is an observational pilot study to quantify the amount of vibration, noise, physiological and biochemical instability that premature babies are exposed to during inter-hospital transport.
- Trial name
- PremiTranS (NCT01851668)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Postpartum Hemorrhage, Venous Thromboembolism
Haemorrhages and Thromboembolic Venous Disease of the Postpartum
The aim of this study is to evaluate the frequencey and the determinants of postpartum major complications (hemorrhage and thrombosis) up to 3 months after delivery in the maternity hospitals of Finistère (Bretagne - France)
- Trial name
- HEMOTHEPP (NCT02443610)
- Where
- 6 sites in France
- Volunteers
- 20,241 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
First Trimester Bleeding, Pregnancy
Early Pregnancy Evaluation by Three-Dimensional Ultrasound
Early pregnancy is associated with numerous physiologic alterations - many of which are required to establish normal pregnancy outcome.
- Trial name
- NCT00342290
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Uterine Atony, Uterine Tone Disorders
Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Insufficient uterine tone resulting in atony can potentiate hemorrhage and adverse outcomes for the parturient. Oxytocin is the first pharmacologic agent used, followed by methylergonovine, carboprost, and misoprostol.
- Conditions
- Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
- Trial name
- NCT03303235
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
IUD, Abnormal Uterine Bleeding
Assessing Pain and Effectiveness of Carevix Device for IUD Insertions
The goal of this clinical trial is to evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between IUD insertions using a suction cervical stabilizer (new device, FDA…
- Conditions
- IUD, Abnormal Uterine Bleeding, Pain, Cervical
- Trial name
- CARE (NCT07290517)
- Testing
- Carevix, Tenaculum
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage
Management of Large Retained Products of Conception (> 4 cm): Need for an Standardized Procedure.
Collection of relevant data form patients who were treated in the Ghent University Hospital in the context of a placental remnant lager than 4 cm, performing statistical analyzes on the collected data, reviewing the literature on…
- Conditions
- Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage, Placenta; Retention, Fragments, Complicating Puerperium (Delayed Hemorrhage), Pregnancy Related
- Trial name
- NCT04720885
- Testing
- kind of surgery
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
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