Clinical trials: Pregnancy Hemorrhage
Postpartum Hemorrhage
A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH)
In this prospective, single-center, randomized, placebo-controlled, double-blind clinical trial, parturients with primary PPH are eligible for treatment with fibrinogen concentrate following both vaginal delivery and cesarean…
- Trial name
- PERFECT PPH (NCT02528708)
- Testing
- fibrinogen concentrate
- Sponsor
- Yale University
ıntrapartum Haemorrhage, Postpartum Haemorrhage
The Effect of Rectal and Sublingual Misoprostol Administration in Postpartum or Intrapartum Haemorrhage at Elective Caesarean Delivery: a Randomized Controlled Trial
The investigators hypothesis in this study is that administration of rectal and sublingual misoprostol decreases intrapartum and postpartum haemorrhage.
- Trial name
- NCT01931410
- Testing
- Misoprostol
- Volunteers
- 618 people
- Sponsor
- Istanbul Bakirkoy Maternity and Children Diseases Hospital
PPH - Postpartum Hemorrhage
Post-Partum Haemorrhage (PPH) Improvement of Skills With Actor Simulations
Pre test and post test questionnaire for evaluation of skills and teamwork capacities in PPH management
- Trial name
- PPH (NCT06358768)
- Testing
- teamwork job improvement overall, teamwork job improvement in actor scenario vs mannequin scenario
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- G. d'Annunzio University
Endometrial Polyp, Endometrial Cancer
Endometrial Polyps: Pathophysiology and Clinical Consequences
The aim of these studies is to study the natural history, the symptoms of, as well as the effect of hysteroscopic resection of endometrial polyps.
- Trial name
- NCT00247923
- Testing
- Hysteroscopic resection of endometrial polyps. (TCRP)
- Where
- Norway
- Volunteers
- 1,186 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Postpartum Hemorrhage, Maternal Morbidity
Secondary Postpartum Hemorrhage
Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality and morbidity worldwide, including in France, where it accounts for approximately 20% of maternal mortality.
- Conditions
- Postpartum Hemorrhage, Maternal Morbidity, Retained Placenta, Postpartum Endometritis
- Trial name
- SPPH (NCT03840889)
- Testing
- Data collection
- Where
- 10 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Placental Expulsion Time
Influence of Acupuncture in the Placental Expulsion Time
In this study, a single blind randomized trial is carried out in order to compare placental detachment times when Ren Mai 6 is stimulated and when a different placebo point is used.
- Trial name
- NCT02000752
- Testing
- Acupuncture
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Cerebral Palsy, Intraventricular Hemorrhage
Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
As many more premature infants survive, the numbers of these infants with health problems increases. The rate of cerebral palsy (CP) in extremely premature infants is approximately 20%.
- Conditions
- Cerebral Palsy, Intraventricular Hemorrhage, Periventricular Leukomalacia, Pulmonary Edema
- Trial name
- BEAM (NCT00014989)
- Testing
- magnesium sulfate
- Where
- 17 sites in United States
- Volunteers
- 2,136 people
- Sponsor
- The George Washington University Biostatistics Center
Uterine Atony, Post-partum Hemorrhage
Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.
- Trial name
- NCT01630187
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Laval University
Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage
HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
The objective of the Expanded Access Program is to provide HEMOLEVEN, a replacement coagulation factor XI, to patients with severe inherited factor XI deficiency where, in the opinion of the treating physician, the benefits of…
- Conditions
- Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage, Surgery
- Trial name
- EAP (NCT01701947)
- Testing
- Hemoleven
- Where
- United States
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Neonatal Mortality, Omphalitis
Newborn Care Kit to Save Lives in GB, Pakistan
Neonatal deaths account for almost half of all deaths in children under 5 years of age. Pakistan has the world's highest neonatal mortality rate (NMR), and many of these deaths are preventable.
- Conditions
- Neonatal Mortality, Omphalitis, Post-Partum Hemorrhage
- Trial name
- iNCK (NCT04798833)
- Testing
- Integrated Newborn Care Kit (iNCK)
- Where
- 2 sites in Pakistan
- Volunteers
- 19,344 people
- Sponsor
- The Hospital for Sick Children
Postpartum Hemorrhage
The Foley's Catheter Balloon to the Bleeding From Placenta Previa
Post-partum haemorrhage due to placenta previa is usually from the placental bed at the lower uterine segment and it occurs after the placenta separation.
- Trial name
- NCT02640885
- Testing
- Foley's cather ballon
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Hematuria, Urothelial Carcinoma
UroCAD for Hematuria Evaluation--A Prospective, Multi-center Study
Hematuria is recognized as an important sigh of potential urinary tract malignancy. Therefore, understanding the disease processes and discovering the potential urothelial carcinoma (UC) underlying this important sign is…
- Trial name
- NCT05893316
- Testing
- urine sample collection
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Uterine Bleeding, Uterine Leiomyomas
Ultrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn Study
Uterine fibroids are benign tumors originating from the uterine muscle, affecting up to 70% of women by their 50s. Risk factors include African descent, nulliparity, obesity, and diabetes.
- Conditions
- Uterine Bleeding, Uterine Leiomyomas, Uterine Hemorrhage, Uterine Neoplasms
- Trial name
- MySaturn (NCT06953076)
- Testing
- Relugolix/estradiol/norethisterone acetate
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Premenstrual Syndrome, Menstrual Cycle
Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms
The goal of this clinical trial is to evaluate the impact of moderate aerobic exercise on menstrual symptom management in sedentary women both using and not using hormonal contraceptives.
- Conditions
- Premenstrual Syndrome, Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Menstrual Bleeding, Heavy
- Trial name
- NCT07084714
- Testing
- Moderate Aerobic Exercise
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Colorado, Colorado Springs
Menstrual Bleeding, Heavy
NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) affects 30% of women worldwide. It negatively influences physical activity, work productivity, sexual life and overall quality of life.
- Trial name
- RAMBOS (NCT05856838)
- Testing
- NovaSure ablation
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Uterine Atony, Uterine Atony With Hemorrhage
Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
Postpartum hemorrhage (PPH) is the leading cause of maternal morbidity and mortality worldwide. Up to 80% of PPH is caused by uterine atony, the failure of the uterine smooth muscle to contract and compress the uterine…
- Conditions
- Uterine Atony, Uterine Atony With Hemorrhage, Postpartum Hemorrhage, Cesarean Section Complications
- Trial name
- CALBLOC (NCT05027048)
- Testing
- Calcium chloride
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Primary, Post Partum Hemorrhage
Prevention of Primary Postpartum Haemorrhage
Postpartum hemorrhage, is one of the most deadly complication of pregnancy worldwide and major cause of maternal mortality especially in third world countries .1 PPH affects about 5% of all women giving birth around the world 2…
- Trial name
- NCT04724187
- Testing
- Misoprostol, Oxytocin
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Blood Loss, Repeat Cesarean Section
Cesarean Scar Pregnancy and Clinical Outcomes
This study is a prospective cohort study, led by Prof. Zhao Yangyu, from the Department of Gynecology \& Obstetrics, Peking University Third Hospital.
- Conditions
- Blood Loss, Repeat Cesarean Section, Maternal Transmission, Hysterectomy
- Trial name
- NCT05481606
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Blood Loss
Validating a New Point-of-care Device for Estimation of Blood Count in Pregnant Women
Postpartum hemorrhage is a well-known complication of delivery and the leading cause of maternal mortality worldwide. In developed nations, a complete blood count (CBC) is commonly collected as a means to assess or base treatment…
- Trial name
- NCT05012202
- Testing
- Hemi device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- The University of Texas Medical Branch, Galveston
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