Clinical trials: Pregnancy Hemorrhage
Hemorrhage, Coagulation Delay
Evaluation of Novel Point of Care Coagulation System in Pregnant Women
In this study the investigators will evaluate a new point of care Quantra Hemostasis Analyzer system to assess coagulation rapidly with ease.
- Trial name
- CCPW (NCT04301193)
- Testing
- Quantra Analyzer
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Uterine Bleeding, Atony, Uterine
Questionnaire for Obstetricians and Anesthesiologist
The research was planned as a face-to-face survey evaluation. The questionnaire will be applied to obstetricians and anesthesiologists working in public and private hospitals.
- Conditions
- Uterine Bleeding, Atony, Uterine, Cesarean Section Complications
- Trial name
- NCT05089721
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Gazi University
Post Partum Hemorrhage
Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery.
Postpartum hemorrhage continues to be the leading cause of maternal morbidity and mortality. Globally, it is responsible for 25% of all pregnancy-related deaths. PPH is unpredictable and may occur in the absence of risk factors.
- Trial name
- NCT06604325
- Testing
- Tranexamic acid injection
- Where
- India
- Volunteers
- 300 people
- Sponsor
- Aligarh Muslim University
Post Partum Hemorrhage
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
The goal of this study is to compare 2 medications that are commonly used to prevent excess uterine bleeding (postpartum hemorrhage, or PPH) following cesarean delivery (CD), oxytocin and carbetocin.
- Trial name
- NCT06333340
- Testing
- Oxytocin, Carbetocin
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Endometrial Neoplasms
Endometrial Lesions Predictions
To explore the risk factors of endometrial lesions in patients with abnormal uterine bleeding and establish prediction models which can discriminate between different endometrial etiologies of abnormal uterine bleeding(AUB).
- Trial name
- NCT05588076
- Testing
- no intervention
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Beijing Friendship Hospital
Urinary Bladder Neoplasms, Sexual Dysfunction, Physiological
Sexual Function in Patients Suspected of Non-muscle Invasive Bladder Cancer
The purpose of the study is to investigate sexual function in patients suspected of non muscle invasive bladder cancer (NMIBC). The investigators hypothesis is that reduced sexual function is underdiagnosed in patients with…
- Conditions
- Urinary Bladder Neoplasms, Sexual Dysfunction, Physiological, Sexual Dysfunctions, Psychological, Erectile Dysfunction
- Trial name
- NCT02381912
- Testing
- EORTC QLQ-C30 and EORTC BLS-24 questionnaire
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Herlev Hospital
Heavy Menstrual Bleeding
Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding
This is a study to learn more about a drug called Tranexamic acid (TA), otherwise known as Lysteda, and whether or not this drug can decrease menstrual blood loss in young women and lead to an increase in the quality of life.
- Trial name
- NCT01846507
- Testing
- Tranexamic Acid
- Where
- 5 sites in United States
- Volunteers
- 32 people
- Sponsor
- Nationwide Children's Hospital
Bladder Cancer, Hematuria
Multi Institutional Study in Patient Presenting With Hematuria
The primary objective of this study is to evaluate the performance of the methylation marker panel for the detection of bladder cancer in patients with gross or microscopic hematuria.
- Trial name
- NCT03122964
- Testing
- AssureMDx
- Where
- United States
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- MDx Health
Observational Study, Dydrogesterone
Observational Study of Dydrogesterone in Cycle Regularization
Dydrogesterone has been widely used worldwide for various gynecological and obstetric indications: Dydrogesterone is effective in cycle regulation treatment.
- Conditions
- Observational Study, Dydrogesterone, Irregular Menstrual Cycle, Abnormal Uterine Bleeding
- Trial name
- NCT02029144
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Fudan University
Teaching Innovation, Midwifery Students Education
Flipped Learning in PPH Education: Impact on Midwifery Students' Knowledge, Skills, Self-Efficacy, and Satisfaction
Maternal death refers to a woman's death due to direct or indirect causes during pregnancy, childbirth, or within 42 days postpartum.
- Conditions
- Teaching Innovation, Midwifery Students Education, Postpartum Hemorrhage, Flipped Classroom Model in Teaching
- Trial name
- NCT06861296
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Abnormal Uterine Bleeding, Abnormal Uterine Bleeding, Ovulatory Dysfunction
Stopping Heavy Periods Project
This study is a randomized clinical trial comparing the effectiveness of the levonorgestrel intrauterine system (LNG-IUS) to combined oral contraceptives (COCs) for improving quality of life among women who report heavy menstrual…
- Conditions
- Abnormal Uterine Bleeding, Abnormal Uterine Bleeding, Ovulatory Dysfunction, Abnormal Uterine Bleeding, Endometrial Hemostatic Dysfunction
- Trial name
- SHiPP (NCT02002260)
- Testing
- Levonorgestrel intrauterine system, Combined oral contraceptives
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Uterine Leiomyoma
Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy
The purpose of this study is to compare the effect of the concentration of vasopressin, which is used as a method for reducing blood loss in robot-assisted laparoscopic myomectomy.
- Trial name
- VALENTINE (NCT04874246)
- Testing
- Vasopressin
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Seoul National University Hospital
Postpartum Hemorrhage
Prevention of Postpartum Haemorrhage With Sublingual Misoprostol or Oxytocin
Sublingual misoprostol produces rapid peak concentration and is more effective than oral misoprostol for prevention of excessive postpartum bleeding.
- Trial name
- NCT01373359
- Testing
- Misoprostol, Oxytocin
- Where
- India
- Volunteers
- 652 people
- Sponsor
- Jawaharlal Nehru Medical College
Menorrhagia
Ultrasound Appearance of the Endometrium Post Radio-Frequency Ablation
The study primarily aims to evaluate the post ablative endometrium and uterus using transvaginal ultrasound to provide descriptive information as to what may be expected in the 12 months after a NovaSure ablation.
- Trial name
- NCT02584088
- Testing
- Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Blood Loss
Internal Iliac Artery Ligation Before Cesarean Hysterectomy in Morbidly Adherent Placenta
40 pregnant females at term diagnosed with morbidly adherent placenta and planned for elective cesarean section were recruited and randomized to 2 groups. Group A: Internal iliac ligation followed by cesarean hysterectomy.
- Trial name
- NCT03824873
- Testing
- Internal iliac artery ligation, cesarean hysterectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Iron Deficiency Anemia, Abnormal Uterine Bleeding
Tolerability of Iron Therapy in Women With AUB
Telephone surveys of female patients using liposomally-bound iron and traditional iron sulphate preparations for the management of iron deficiency anemia to determine gastrointestinal tolerability.
- Trial name
- NCT04915196
- Testing
- Liposomally-bound Iron
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Heavy Menstrual Bleeding
Transcutaneous Auricular Neurostimulation as a Treatment for Women With Heavy Menstrual Bleeding: A Dose-finding Trial
This study is designed as an open label, single-arm, decentralized research study in which patients with idiopathic heavy menstrual bleeding will receive transcutaneous auricular neurostimulation (tAN), which targets the…
- Trial name
- NCT06814028
- Testing
- Volta System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spark Biomedical, Inc.
Endometrial Polyp, Endometrial Cancer
Endometrial Polyps: Pathophysiology and Clinical Consequences
The aim of these studies is to study the natural history, the symptoms of, as well as the effect of hysteroscopic resection of endometrial polyps.
- Trial name
- NCT00247923
- Testing
- Hysteroscopic resection of endometrial polyps. (TCRP)
- Where
- Norway
- Volunteers
- 1,186 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Uterine Bleeding
Tranexamic Acid and Depot-Medroxyprogesterone Acetate for Perimenopausal Irregular Uterine Bleeding
Abnormal uterine bleeding is a symptom and not a disease. It is one of the most frequently encountered complaints in gynecologic practice.
- Trial name
- NCT04710017
- Testing
- Tranexamic acid, Medroxyprogesterone Acetate 150 MG/ML
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Leiomyoma, Uterine Hemorrhage
A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas
This study will evaluate the superiority of ulipristal acetate versus placebo for the treatment of abnormal uterine bleeding associated with uterine fibroids
- Trial name
- NCT02147197
- Testing
- Ulipristal acetate (UPA)
- Where
- 28 sites in United States
- Volunteers
- 157 people
- Sponsor
- Allergan
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