Clinical trials: Pregnancy Induced Hypertension
IVF, Frozen Embryo Transfer (FET)
Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)
Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).
- Conditions
- IVF, Frozen Embryo Transfer (FET), Cardiovascular Adaption, Magnetic Resonance Imaging (MRI)
- Trial name
- NCT06471140
- Testing
- magnetic resonance imaging (MRI)
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Preeclampsia
Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
The purpose of the study is to assess the efficacy, safety and pharmacokinetics (PK) of recombinant human antithrombin (ATryn) in addition to expectant management for the treatment of preterm preeclampsia (PPE).
- Trial name
- PRESERVE-1 (NCT02059135)
- Testing
- Recombinant human antithrombin (ATryn), Normal Saline 0.9%
- Where
- 23 sites in United States
- Volunteers
- 120 people
- Sponsor
- rEVO Biologics
Heart Failure, Diastolic Dysfunction
Timely Recovery After Subclinical Heart Failure
The goal of this randomized controlled trial is to assess the effectiveness of ACE inhibitors versus standard care) in reversing asymptomatic heart failure (HF stage-B) and/or diastolic dysfunction during a two-year open-label…
- Trial name
- TREASURE (NCT06341101)
- Testing
- Perindopril
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Hypertension, Pregnancy-Induced
A Clinical Study of Fundus Findings in Toxaemia of Pregnancy
Toxemia of pregnancy is a recognized entity for over 2000 years with its known complications and fatality. Nowadays, a most accepted terminology for the following defined syndrome is "hypertensive disorders in pregnancy" given by…
- Trial name
- NCT03076619
- Testing
- clinical ophthalmoscopy
- Where
- India
- Volunteers
- 300 people
- Sponsor
- B. J. Medical College, Ahmedabad
Preeclampsia
Spinal Anaesthesia and Severe Preeclampsia
The use of spinal anesthesia in pre-eclamptic pregnant woman is of considerable benefit, as these patients present particular hazards with general anaesthesia, such as concerns for rapid airway control and cerebral blood flow…
- Trial name
- NCT02633995
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Hypertension in Pregnancy
Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy
The purpose of this study is to evaluate the effects of oral L-Arginine in pregnant women with chronic hypertension.
- Trial name
- NCT00571766
- Testing
- L-Arginine
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Hypertension (HTN), Hypertension ,Pregnancy
REmote Physical ACtivity Intervention for High Blood Pressure Postpartum
The purpose of this intervention is to help new mothers who had elevated blood pressure during pregnancy become more physically active after birth. The investigators will connect data from FitBits to the electronic health record.
- Conditions
- Hypertension (HTN), Hypertension ,Pregnancy, Physical Activity
- Trial name
- REACH BP (NCT07127731)
- Testing
- Patient Portal Messaging, FitBit EHR Linkage
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Preeclampsia and Eclampsia
Springfusor for Administration of Magnesium Sulphate in Preeclampsia and Eclampsia
Magnesium Sulphate is the drug of choice for prevention and treatment of seizures in preeclampsia and eclampsia. It is administered parenterally by intravenous (IV) and or intramuscular (IM) routes.
- Trial name
- NCT03549767
- Testing
- Springfusor, Standard of care
- Where
- Uganda
- Volunteers
- 241 people
- Sponsor
- Makerere University
Hypertension in Pregnancy, Postpartum Preeclampsia
Rhode Island - Statewide Postpartum Hypertension Remote Surveillance
This is a hybrid type 1 non-inferiority implementation effectiveness trial among postpartum patients with hypertension (N=1536) that will test the hypothesis that RI-SPHERES (a technologically enabled collaborative care model) is…
- Conditions
- Hypertension in Pregnancy, Postpartum Preeclampsia, Postpartum Complication
- Trial name
- RI-SPHERES (NCT06842875)
- Testing
- RI-SPHERES, Standard self-measured blood pressure program
- Where
- 5 sites in United States
- Volunteers
- 1,536 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Preeclampsia
Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients
Admission CTG for 20 minutes Settings on a CTG machine was standardised to enable a consistent approach of interpretation of traces. Paper speed of 3cm per minute will be adopted.
- Trial name
- NCT03237000
- Testing
- MgSO4
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Preeclampsia, Preeclampsia Complications
Role of Progesterone Membrane Receptors in the Pathogenesis of Preeclampsia
Preeclampsia is a pregnancy-specific hypertensive disorder and remains a leading cause of maternal and perinatal morbidity and mortality worldwide.
- Trial name
- NCT07745036
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Samsun University
Sleep Disordered Breathing, Obstructive Sleep Apnea
Sleep Disordered Breathing and Gestational Hypertension
Sleep disordered breathing (SDB) is a common problem in the adult population. By conservative estimates, 4% of the adult female population has SDB.
- Conditions
- Sleep Disordered Breathing, Obstructive Sleep Apnea, Gestational Hypertension, Preeclampsia
- Trial name
- NCT00757718
- Testing
- CPAP, Oral Appliance
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Saskatchewan
Preeclampsia
Randomizated Open-label Control Trial to Evaluate if the Incorporation of sFlt1/PlGF Ratio in the Diagnosis and Classification of PE Improves Maternal and Perinatal Outcomes in Women With the Suspicion of the Disease
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality worldwide. The morbidity and mortality of this condition arises from two main causes: 1) the lack of specific and sensible methods for its diagnosis…
- Trial name
- EuroPE (NCT03231657)
- Testing
- Placental biomarkers
- Where
- Spain
- Volunteers
- 2,536 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Preeclampsia, Pregnancy Complications
Climate-Safe Pregnancy Intervention for Women With Preeclclampsia
This randomized controlled trial aims to evaluate the effectiveness of a climate-related nursing intervention in improving pregnancy-specific climate change knowledge, health beliefs, and protective behaviors among pregnant women…
- Conditions
- Preeclampsia, Pregnancy Complications, Climate Change and Maternal Health
- Trial name
- NCT07564856
- Testing
- Climate-Related Nursing Intervention, Routine Antenatal Care
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Benha University
Preeclampsia
Prevalence Study of Sleep Apnea in Women With Preeclampsia
Hypothesis: The prevalence of sleep apnea is greater in pregnant women with preeclampsia than in pregnant women without preeclampsia.The presence of sleep apnea will be associated with poor blood pressure control, worsening blood…
- Trial name
- NCT00259688
- Testing
- CPAP therapy for subjects diagnosed with sleep apnea
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
HELLP Syndrome
General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome
Anesthesia for caesarian section in patients with HELLP syndrome is a challenge. Measures should be taken during caesarian delivery to guard against the maternal and fetal complications associated with HELLP syndrome.
- Trial name
- NCT03111446
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypertension in Pregnancy, Gestational Hypertension
Virtual Cardiac Wellness Program Following Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy (HDP) are now well-recognized risk factors for adverse outcomes in the postpartum period and for development of future cardiovascular disease (CVD).
- Conditions
- Hypertension in Pregnancy, Gestational Hypertension, Preeclampsia, Chronic Hypertension With Pre-Eclampsia
- Trial name
- NCT04998942
- Testing
- virtual cardiac wellness program
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Pre-Eclampsia
L-Arginine in Pre-Eclampsia
Pre-eclampsia is a disorder unique to pregnancy affecting both the mother and the fetus. Hypertension, proteinuria and edema are the most common and well-known maternal clinical symptoms. The incidence is approximately 6-8%.
- Trial name
- NCT00157521
- Testing
- L-arginine
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pre-Eclampsia
Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia
Preeclampsia is globally responsible for tens of thousands of maternal and neonatal deaths each year. Currently, there are no medical therapies to halt disease progression and expectant management and delivery remain the mainstay…
- Trial name
- NCT03717701
- Testing
- metformin, esomeprazole
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Aswan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.