Clinical trials: Pregnancy Induced Hypertension
Preeclampsia
Longitudinal Study: Diagnosis and Prediction of Pre-Eclampsia by Using Congo Red Dot Test in Bangladesh and Mexico
A population-based prospective cohort design will evaluate the progression of urine congophilia in pregnancy using the Congo Red Dot test by following patients longitudinally across gestation in Bangladesh and Mexico City.
- Trial name
- NCT02381197
- Testing
- Congo Red Dot test
- Where
- 2 sites in Bangladesh, Mexico
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Preeclampsia Severe, Toxemia Of Pregnancy
LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention
Preeclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. Low-dose aspirin started in the first trimester reduces the risk of preeclampsia in high-risk women.
- Conditions
- Preeclampsia Severe, Toxemia Of Pregnancy, Preeclampsia, Pregnancy Complications
- Trial name
- preGO (NCT07361679)
- Testing
- Aspirin, Tinzaparin
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Alexandra Hospital, Athens, Greece
Pre-Eclampsia, Cathepsin B Level
The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy
In this study, the investigator aim was to compare Cathepsin B and Pentraxin 3 levels measured from maternal serum of pregnant women diagnosed with preeclampsia in the second trimester, the effects of these levels on maternal/…
- Conditions
- Pre-Eclampsia, Cathepsin B Level, Pentraxin 3 Level
- Trial name
- NCT05924061
- Testing
- Cathepsin B and pentraxin 3 levels in preeclampsia with pregnant women
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Preeclampsia
Fetal Renal Artery Doppler in Patients With Preeclampsia
Preeclampsia is a major devastating disorder affects 2:10% of pregnancies worldwide. preeclampsia may be associated with placental insufficiency which may cause fetal blood redistribution to essential organs like brain, heart…
- Trial name
- NCT06395974
- Testing
- fetal ultrasound
- Where
- Egypt
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pregnancy Related, Diet Modification
Effects of Diet on Pregnancy Outcome and Child Obesity
The purpose of the study is to compare 3 different diets in pregnancy, equal in calories, and fats, different in refined grains compared to whole grains as a source of carbohydrates, and in calories from carbohydrate, compared to…
- Conditions
- Pregnancy Related, Diet Modification, Obesity, Hypertension
- Trial name
- NCT03232762
- Testing
- Refined Grains, Whole Grains
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
HELLP Syndrome
General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome
Anesthesia for caesarian section in patients with HELLP syndrome is a challenge. Measures should be taken during caesarian delivery to guard against the maternal and fetal complications associated with HELLP syndrome.
- Trial name
- NCT03111446
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Preeclampsia
EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)
The goal of this prospective observational cohort study of pregnant people at-risk of preeclampsia receiving aspirin as part of clinical care or a planned randomized controlled trial of 81mg vs.
- Trial name
- NCT06249178
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Ohio State University
Hypertension, Hypertension in Pregnancy
Telehealth and Remote Blood Pressure
The purpose of this research study is to compare the management of chronic hypertension during pregnancy using telehealth visits with blood pressure telemonitoring and health coaching as compared to standard in person clinic…
- Trial name
- NCT07356518
- Testing
- Telehealth visits, In-person visits
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Preeclampsia, Severe Preeclampsia
Identification of Genes of Interest for Severe Forms of Preeclampsia
Preeclampsia is a pregnancy complication characterized by high blood pressure associated with damage to various organs, especially the kidneys.
- Trial name
- PRE-OMIQUES (NCT07703826)
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Hypertension in Pregnancy
STAMPP-HTN in a High-risk Rural Population of Women
The purpose of this study is to determine if monitored blood pressure paired with education reduces maternal mortality and morbidity during the post-partum period in a high-risk rural population of women.
- Trial name
- NCT04570124
- Testing
- Home Blood Pressure Telemonitoring
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Mississippi Medical Center
HELLP Syndrome (HELLP), Third Trimester, Complement Abnormality
The Use of Eculizumab in HELLP Syndrome
This research study is being performed to see if women diagnosed with early preterm Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) syndrome (estimated gestational ages of 23-30 weeks) benefit from a medication called…
- Conditions
- HELLP Syndrome (HELLP), Third Trimester, Complement Abnormality, Morbidity;Newborn, Maternal Injury
- Trial name
- NCT04103489
- Testing
- Eculizumab
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Preeclampsia
Cornell University-Micronutrient Initiative Calcium Supplementation Study
The World Health Organization (WHO) now recommends prenatal calcium supplementation for prevention of preeclampsia in populations with inadequate dietary intake.
- Trial name
- MICA (NCT02238704)
- Testing
- Regimen A calcium and iron/folic acid, Regimen B calcium and iron/folic acid
- Where
- 16 sites in Kenya
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Cornell University
Preeclampsia, Periodontal Disease
Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease
The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preeclampsia.
- Trial name
- NCT03603236
- Testing
- preeclampsia, control
- Where
- 5 sites in Turkey (Türkiye), United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Preterm Birth, Intrauterine Growth Retardation
Fish Oil Trials in Pregnancy for the Prevention of Pregnancy Complications ('FOTIP')
The initial trial examined if fish oil supplementation during pregnancy could reduce the risk of pregnancy induced hypertension, intrauterine growth retardation, and preterm birth in pregnancies that were at increased risk of…
- Conditions
- Preterm Birth, Intrauterine Growth Retardation, Pregnancy Induced Hypertension
- Trial name
- FOTIP (NCT02229526)
- Testing
- Low dose fish oil, Low dose olive oil, High dose fish oil
- Volunteers
- 1,619 people
- Sponsor
- Sjurdur Frodi Olsen
Hypertension in Pregnancy
Invasive Versus Non-invasive Assessment of Blood Pressure in Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy are important causes of maternal morbidity and mortality worldwide. Hypertension is one of the most commonly reported health conditions among pregnant women and complicates 5-10% of all…
- Trial name
- NCT04303871
- Testing
- Invasive blood pressure assessment by radial artery canulation
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- Assiut University
Pre-Eclampsia
Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia
Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery >34 weeks) is more frequent and less serious than early preeclampsia (with delivery…
- Trial name
- NCT03838887
- Testing
- ultrasound machine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Pre-Eclampsia
Screening for Preeclampsia in Norway With Aspirin Discontinuation at 24-28 Weeks
Study population Around 3500 pregnant women attending a routine ultrasound scan at 11-14 weeks at St. Olavs hospital, Trondheim, Norway.
- Trial name
- PEScreenNor (NCT06108947)
- Testing
- Aspirin
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Pregnancy
PLAC1 in Reproduction
The PLAC1 gene is a recently described X-linked gene that maps to a region of the X chromosome thought to be important for normal fetal and placental development.
- Trial name
- NCT01277848
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pre-Eclampsia, Volume Overload
PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA
BACKGROUND: A cornerstone of treatment in preeclampsia is to correct the potential hypovolemia with intravascular optimisation, which is usually performed as a fluid challenge.
- Conditions
- Pre-Eclampsia, Volume Overload, Hemodynamic Instability
- Trial name
- NCT03755843
- Testing
- PASSIVE LEG RISING
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- RAUL CARRILLO ESPER
Hypertension in Pregnancy, Hypertension, Pregnancy-Induced
Innovation in Postpartum Care for Women With Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy (HDP) affect up to 10% of mother-infant dyads and account for 7.4% of cases of maternal mortality in the United States.
- Conditions
- Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Postpartum Preeclampsia, Blood Pressure Disorders
- Trial name
- NCT03613714
- Testing
- At-home Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
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