Clinical trials: Pregnancy Induced Hypertension
Preeclampsia
Assessment of Volume Status in Preeclampsia Post- SpinalAnasthesia:Utilizing Ultrasound " Evaluation of Lung and Inferior Vena Cava"
Primary aim Assess the accuracy and reliability of ultrasound evaluation of lung and inferior vena cava in determining volume status post-spinal anesthesia in pre-eclampsia patients.
- Trial name
- AComparative (NCT07514130)
- Testing
- Ultrasound lung, ultrasound for IVC diameter, Intrathecal bupivacane
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Menoufia University
Preeclampsia
Daily Aspirin Treatment After Preeclampsia
Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy.
- Trial name
- NCT06168461
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Anna Stanhewicz, PhD
Airway Assessment
Ultrasonographical Assessment of Airway Indices in Pregnancy
Clinical and ultrasound indices of airway, in addition to laryngoscopic view will be assessed and compared among three groups of patients: non pregnant, pregnant with normal blood pressure, preeclampsia patients undergoing…
- Trial name
- NCT07423741
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- South Valley University
Preeclampsia, Oocyte-donation Pregnancies
Immunological and Cardiovascular Phenotyping of Oocyte-donation Pregnancies
The investigators conduct a study to evaluate the underlying causes of preeclampsia in oocyte-donation pregnancies.
- Trial name
- NCT04731012
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Gestational Diabetes Mellitus, Hypertension in Pregnancy
Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)
STEP-UP will promote linkage to primary care and ongoing chronic disease evaluation for postpartum women with prior gestational diabetes mellitus (GDM) and/or hypertensive disorders of pregnancy (HDP).
- Conditions
- Gestational Diabetes Mellitus, Hypertension in Pregnancy, Dysglycemia
- Trial name
- NCT05852054
- Testing
- OB Provider Clinical Decision Support (CDS), Patient Education (OB Visit), Text messaging
- Where
- 2 sites in United States
- Volunteers
- 2,306 people
- Sponsor
- Northwestern University
Pre-Eclampsia
Preeclampsia Associated Vascular Aging
To evaluate cardiovascular health, especially endothelial health, of women after pre-eclampsia compared to women without pre-eclampsia, and to compare women who had taken PETN during pregnancy with women who had not attempted…
- Trial name
- PAVA (NCT04484766)
- Testing
- Primary data collection
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Jena University Hospital
Hypertension in Pregnancy
Hypertensive Pregnant Women Monitored by Teletransmitted Self-measurements of Blood Pressure
The occurrence of arterial hypertension (AH) during pregnancy is a major cause of fetal, neonatal and maternal morbidity and mortality in western countries.
- Trial name
- FETH (NCT03648645)
- Testing
- Self measurement of blood pressure
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Hypertension, Pregnancy-Induced
Comparison of Urine Protein/Creatinine Ratio With 24-hour Urine Protein Excretion in Woman With Hypertensive Disorders
The presence of proteinuria (>300 mg/d) represents an important factor in the diagnosis and evaluation of the pregnant patient with an hypertensive disorder.
- Trial name
- NCT01508208
- Testing
- Hypertensive disorder of pregnancy
- Where
- Panama
- Volunteers
- 420 people
- Sponsor
- Saint Thomas Hospital, Panama
Pre-Eclampsia
Association Between Pococyturia and Pre-eclampsia Severity
Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity.
- Trial name
- PEPOD2 (NCT03316391)
- Testing
- Dosage of urinary podocyturia
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon
Pre-Eclampsia
Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence
The reason for having a higher incidence of preeclampsia in primiparas may involve angiogenesis imbalance in these patients.
- Trial name
- NCT00262093
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pre-eclampsia
Saccadic Reaction Time and Preterm Pre-eclampsia
This study is recruiting two groups of women over the age of 18; those who are pregnant and who have pre-eclampsia; and those who are pregnant but do not have pre-eclampsia.
- Trial name
- NCT02613793
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Preeclampsia
Effect of Rosuvastatin on the Clinical Features of Preeclampsia
The primary outcome will be the effect of rosuvastatin on the resolution of biochemical features associated with severe PE (↑CRP and IL6). .
- Trial name
- NCT04303806
- Testing
- rosuvastatin
- Volunteers
- 80 people
- Sponsor
- Assiut University
Preeclampsia (PE) Risk, Oocyte Donation
Preeclampsia and Defective Placentation in Oocyte Donation: Importance of HLA-C and KIR
The IMMUN-OR study aims to study HLA-C/KIR combinations when looking at the risk of development of preeclampsia (PE) in pregnancies after oocyte donation.
- Trial name
- IMMUN-OR (NCT07178652)
- Volunteers
- 2,325 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pre-Eclampsia, Placenta Diseases
Trial of Early Screening Test for Pre-eclampsia and Growth Restriction
A study of aspirin use in pregnancy to prevent high blood pressure and growth restriction of the fetus
- Conditions
- Pre-Eclampsia, Placenta Diseases, Eclampsia Preeclampsia, Fetal Growth Retardation
- Trial name
- TEST (NCT03674606)
- Testing
- Low dose aspirin
- Where
- 2 sites in Ireland
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Preeclampsia, Hypertensive Disorder of Pregnancy
Cardiovascular Protection After Preeclampsia With Enalapril
The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
- Conditions
- Preeclampsia, Hypertensive Disorder of Pregnancy, Hypertension, Gestational Hypertension
- Trial name
- CAPP-E (NCT07222852)
- Testing
- Enalapril, Standard treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Preeclampsia, Recurrence
Effects of Recurrent PE on Women and Offspring
The purpose of this study is to evaluate the risk factors of recurrent preeclampsia and compare the short-term and long-term adverse outcomes of women and their offspring.
- Conditions
- Preeclampsia, Recurrence, Hypertension
- Trial name
- RPOH (NCT05134285)
- Testing
- blood pressure,BMI, blood sample
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dunjin Chen
Preeclampsia, Hypertension
Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure
The purpose of this study is to identify whether sleep-disordered breathing - as measured by overnight polysomnography - is associated with pre-eclampsia and to determine whether use of positive airway pressure can improve…
- Trial name
- NCT01029691
- Testing
- Positive Airway Pressure
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Pre-Eclampsia
Study for Improving Maternal, Pregnancy and Child Outcomes
The overall aims of this proposal are to improve, facilitate, optimize and equalize the existing screening system for adverse pregnancy outcomes in early pregnancy in order to limit adverse consequences for both the mother and…
- Trial name
- IMPACT (NCT03831490)
- Testing
- history
- Where
- 9 sites in Sweden
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Preeclampsia
Knowledge and Attitude of Pregnant Women Towards Preeclampsia in Assiut Governorate
Our study will be a cross sectional study to evaluate the knowledge level and attitude of pregnant women towards preeclampsia and factors affecting it ,the study will be done at Assiut University Hospitals - Women's Health…
- Trial name
- NCT05955690
- Where
- Egypt
- Volunteers
- 261 people
- Sponsor
- Assiut University
Gestational Hypertension
Role of the Oral Microbiome in Blood Pressure Regulation in Pregnancy
High blood pressure in pregnancy is associated with poor outcomes for both mum and baby, increasing the risk of pregnancy complications including pre-eclampsia, fetal growth restriction and preterm birth.
- Trial name
- NCT03930693
- Testing
- Beetroot juice
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manchester
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