Clinical trials: Pregnancy Induced Hypertension
Preeclampsia
Chronic Remote Ischemic Preconditioning as a Complement to Conventional Prenatal Care for Preeclampsia
Pre-eclampsia is a disease specific to pregnancy that affects 3-5% of women. It is defined by the appearance of high blood pressure after 20 weeks of amenorrhea associated with the presence of proteins in the urine, dysfunction…
- Trial name
- RIPC (NCT05564988)
- Testing
- Preconditionning
- Volunteers
- 58 people
- Sponsor
- DAVID DESSEAUVE
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Postpartum Hypertension Study
The purpose of this study is to assess which blood pressure medication (intravenous labetalol or oral nifedipine) works better in treating severely elevated blood pressure in women who have just delivered a baby.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
- Trial name
- NCT05139238
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Preeclampsia, Pregnancy Loss
Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia
Use of Juice Plus+ food supplements, when initiated in the first trimester and used continuously thereafter, will result in a lower incidence of preeclampsia and pregnancy complications.
- Trial name
- NCT00583635
- Where
- United States
- Volunteers
- 684 people
- Sponsor
- University of Mississippi Medical Center
Hypertension Disorders in Pregnancy, Gestational Hypertension
Vascular Biomarkers Predictive of the Progression From Hypertensive Disorders in Pregnancy to Preeclampsia in Pregnant Women
Hypertension during pregnancy remains a leading cause of maternal and fetal morbidity and mortality. The frequency (5 to 10% of pregnancies) and potential severity of these diseases, both for the mother and the child, are reasons…
- Conditions
- Hypertension Disorders in Pregnancy, Gestational Hypertension, Pre-Eclampsia
- Trial name
- BIOVASC-PreHTA (NCT04520048)
- Testing
- Determination of the UEMP levels, Aortic central pressure and the carotid-femoral pulse wave velocity, Vascular biomarker assay
- Where
- 3 sites in France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pre-Eclampsia, Critical Illness
Homocysteine in Critically Ill Preeclampsia
Preeclampsia is a disorder characterized by the new onset of hypertension and proteinuria typically presenting after 20 weeks of gestation.
- Trial name
- NCT06413576
- Testing
- homocysteine measurement
- Where
- 2 sites in Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypertension in Pregnancy, Hypertension in Postpartum
Is Procardia XL 60 mg Q Daily Equivalent to 30 mg XL Given Twice Daily?
Antihypertensive therapy has been used in pregnant patients antepartum to improve blood pressure (BP) elevation in cases of chronic hypertension, and postpartum for persistent hypertension after delivery in cases of gestational…
- Trial name
- NCT03595982
- Testing
- Procardia XL 30Mg, Procardia XL 60Mg
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder, Asthma
Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social…
- Conditions
- Autism Spectrum Disorder, Asthma, Executive Dysfunction, Emotional Problem
- Trial name
- NCT03269110
- Testing
- SRS 2, CBCL, BRIEF-P
- Where
- 58 sites in Australia, Canada and 2 more
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Preeclampsia Severe, Preeclampsia Postpartum
Biomarkers in Management of Post Partum Preeclampsia
Participants are recruited for a research study about how lab values change following delivery in people with Preeclampsia with Severe Features.
- Trial name
- NCT07478055
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alexander Harrison
Pre-eclampsia, Pre-Eclampsia, Severe
Prevalence of Blood Pressure Complications During Cesarean Section in Pre-eclamptic Patients (HOPE)
Preeclampsia (PE) is an obstetric placental vascular pathology with a prevalence of 2 to 5% of pregnant women. It is defined by learned societies by the association of high blood pressure (BP≥140/90mmHg) and proteinuria \&gt…
- Trial name
- HOPE (NCT06588023)
- Testing
- Observational study to evaluate professional practices
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Preeclampsia
Maternal Serum Stathmin-1 Levels in Preeclampsia
The goal of this observational study is to investigate maternal serum Stathmin-1 levels in pregnancies affected by preeclampsia compared to healthy gestations. The main questions it aims to answer are: 1.
- Trial name
- MSSLP (NCT06481683)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Burak Yücel Special Clinic
Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
Meditation as Complementary Treatment for Chronic Hypertension in Pregnancy
Pregnancy relates to arterial hypertension; it is an aggravating factor for pre-existing chronic arterial hypertension or a trigger for preeclampsia in normotensive women.
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension in Pregnancy, Hypertension
- Trial name
- NCT03873194
- Testing
- Meditation, conventional treatment
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- University of Sao Paulo General Hospital
HELLP Syndrome
Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome
Corticotherapy accelerates maternal postpartum recovery in women with class I HELLP syndrome. The benefit of faster and better recovery would be observed in fewer complications, less utilization of blood products and shorter…
- Trial name
- COHELLP (NCT00711841)
- Testing
- dexamethasone
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Vitamin D Deficiency, Pre-Eclampsia
Vitamin D in Pregnancy
Danish pregnant women are recommended ad daily vitamin D supplement of 10 µg. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an…
- Conditions
- Vitamin D Deficiency, Pre-Eclampsia, Fetal Growth Retardation, Gestational Diabetes
- Trial name
- GRAVITD (NCT04291313)
- Testing
- Vitamin D3 (90µg), Vitamin D3 (10µg)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cardiovascular Diseases, Heart Diseases
Hypertensive and Normal Pregnancy--Calcium Metabolism and Renin-Angiotensin - SCOR in Hypertension
To study calcium metabolism and the renin-angiotensin system in hypertensive and normal pregnancy.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Eclampsia
- Trial name
- NCT00005456
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pre-Eclampsia, Severe, HELLP Syndrome
Promising Bimarker Prediction of Outcome of HELLP Syndrome.
HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia.
- Conditions
- Pre-Eclampsia, Severe, HELLP Syndrome, Microangiopathy
- Trial name
- NCT03246542
- Testing
- shistocytes percentage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AYMAN ABDELKADER MOHAMED ABDELKADER
Pre-Eclampsia
Restrictive Fluid Therapy in Severe Preeclampsia
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation.
- Trial name
- NCT02214186
- Testing
- Restrictive Fluid Therapy
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Spinal Anesthesia-Induced Hypotension, Preeclampsia
Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotension in Preeclamptic Parturients
This prospective, single-center observational study aims to evaluate the predictive value of the internal jugular vein collapsibility index (IJVCI) for spinal anesthesia-associated hypotension in preeclamptic parturients…
- Conditions
- Spinal Anesthesia-Induced Hypotension, Preeclampsia, Cesarean Section
- Trial name
- NCT07496788
- Testing
- Internal Jugular Vein Collapsibility Index Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Reproductive Effects, Pregnancy
Vitamin D and Pregnancy: Camden Study
Vitamin D is present in food either naturally or by fortification and included in nutritional supplements. It is also synthesized photochemically by the skin from ultraviolet B radiation.
- Trial name
- NCT02032459
- Where
- United States
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- Rowan University
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