Clinical trials: Pregnancy Malaria
Malaria, Malaria in Pregnancy
Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component
Our objective was to investigate the importance of malaria infection/disease during pregnancy and more particularly during the first trimester; we also looked at the maternal-foetal interactions and their influence on the…
- Trial name
- NCT00680732
- Testing
- Multiple micronutrients supplements (MMS), Iron and folic acid (IFA), Chloroquine (CQ)
- Where
- Burkina Faso
- Volunteers
- 1,370 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Malaria, Pregnancy
A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda
SUMMARY Background: Malaria is the leading cause of morbidity and mortality among pregnant women in Uganda. Although effective tools for prevention and control of malaria exist, their delivery presents a problem.
- Conditions
- Malaria, Pregnancy, Anemia
- Trial name
- NCT00118027
- Testing
- sulphadoxine-pyrimethamine intermittent preventive treatment
- Where
- Uganda
- Volunteers
- 2,150 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Diabetes, Hypercholesterolemia
Baromètre Santé Adulte 2021-2022
In 2021-2022, Agence Sanitaire et Sociale Nouvelle Calédonie (ASSNC) is undertaking the "Baromètre Santé Adulte" for the third time.
- Conditions
- Diabetes, Hypercholesterolemia, Renal Failure, Dengue Fever
- Trial name
- NCT05218304
- Testing
- Blood sample
- Where
- New Caledonia
- Volunteers
- 5,471 people, healthy volunteers welcome
- Sponsor
- Agence Sanitaire et Sociale de Nouvelle Calédonie
Malaria, Malaria in Pregnancy
Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy
This trial tests the hypothesis that intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) plus dihydroartemisinin-piperaquine (DP) significantly reduces the risk of malaria infection (primary…
- Conditions
- Malaria, Malaria in Pregnancy, Pregnancy Related
- Trial name
- SAPOT (NCT05426434)
- Testing
- Dihydroartemisinin-Piperaquine (DP), Sulfadoxine pyrimethamine (SP)
- Where
- Papua New Guinea
- Volunteers
- 1,172 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Malaria in Pregnancy, Pregnancy
Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP)
AZITHROMYCIN VERSUS SULPHADOXINE-PYRIMETHAMINE FOR PROPHYLAXIS AGAINST MALARIA IN PREGNANCY IN OWO, SOUIHWESTERN NIGERIA: A RANDOMISED CONTROLLED TRIAL OBJECTIVE: This study is to compare the efficacy of Azithromycin versus…
- Trial name
- NCT03944317
- Testing
- Sulfadoxine pyrimethamine, Azithromycin
- Where
- Nigeria
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Federal Medical Centre, Owo
Malaria, Placental Malaria
Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria
This study seeks to determine whether screening pregnant women for malaria with malaria rapid diagnostic tests (RDTs) may detect placental infection and predict risk of poor birth outcomes due to malaria in areas of varied…
- Conditions
- Malaria, Placental Malaria, Malaria in Pregnancy
- Trial name
- NCT01555255
- Where
- 2 sites in Burkina Faso, Uganda
- Volunteers
- 1,205 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Pregnancy
IPTp Plus ITNs for Malaria Control in Pregnant Women
We aim to evaluate whether IPT in pregnancy provides any additional benefit to the protection afforded by ITNs.
- Trial name
- NCT00209781
- Testing
- Sulfadoxine-Pyrimethamine (Fansidar), ITNs
- Where
- Mozambique
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Malaria, Pregnancy
Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy
The incidence of malaria, including the incidence in pregnant women, is declining in many African countries. Thus, there is a need to re-examine the efficacy and cost effectiveness of giving intermittent preventive treatment with…
- Conditions
- Malaria, Pregnancy, Anaemia
- Trial name
- IPTp_IST (NCT01084213)
- Testing
- Intermittent screening and treatment of malaria in pregnancy (IST), SP-IPTp
- Where
- 4 sites in Burkina Faso, Ghana and 2 more
- Volunteers
- 5,354 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Plasmodium Vivax Malaria
Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV)
The current treatment recommendations for P. vivax in pregnant and non-pregnant individuals are to use chloroquine; in non-pregnant patients this is followed by primaquine to prevent relapse.
- Trial name
- PAACT-PV (NCT01107145)
- Testing
- Mefloquine- Artesunate, Artemether-Lumefantrine, Chloroquine
- Where
- 3 sites in Brazil
- Volunteers
- 16 people
- Sponsor
- Centers for Disease Control and Prevention
Anaemia, Malaria
Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment
Malaria is one of the major causes of illness and mortality in Sub-Saharan Africa. In Ghana, malaria is the most important cause of morbidity and accounts for about 40% of outpatient contacts.
- Trial name
- NCT00258024
- Testing
- IPT-sulphadoxinepyrimethamine
- Where
- Ghana
- Volunteers
- 420 people
- Sponsor
- DBL -Institute for Health Research and Development
Malaria, Sexually Transmitted Diseases
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth
The purpose of this study is to examine whether treatment of pregnant Malawian women with repeated doses of sulfadoxine-pyrimethamine and azithromycin antibiotics will prevent preterm deliveries and result in other health…
- Conditions
- Malaria, Sexually Transmitted Diseases, Preterm Birth, Pregnancy
- Trial name
- NCT00131235
- Testing
- Sulfadoxine-pyrimethamine treatment twice during pregnancy, Sulfadoxine-pyrimethamine at 4-week intervals, Sulfadoxine-pyrimethamine every 4 weeks + azithromycin twice
- Where
- Malawi
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Tampere University
Intermittent Preventive Treatment, Placental Malaria
Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda
The effectiveness of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy in malaria-endemic areas the effectiveness and efficacy of SP may be compromised by increased SP resistance.
- Trial name
- SP IPTp (NCT01184911)
- Testing
- Sulfadoxine-pyrimethamine
- Where
- Uganda
- Sponsor
- University of California, San Francisco
Malaria
Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women
This is a clinical trial being done to find better ways to reduce malaria in the community. Malaria is caused by a parasite that is spread by mosquitoes.
- Trial name
- NCT07358767
- Testing
- Artemether-lumefantrine (AL)
- Where
- Ghana
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Pregnancy, Malaria
Safe Pregnancy by Infectious Disease Control
Malaria and sexually transmitted infections (STIs) are common in pregnant women in Africa and are important preventable causes of poor birth outcomes and maternal and infant mortality.
- Trial name
- NCT00489619
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 2,008 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Malaria, Pregnancy, Malaria, Antepartum
Safety of Antimalarials in the FIRst trimEster
The SAFIRE study aims to find effective treatments with acceptable safety for malaria in early pregnancy, a particularly sensitive time for the adverse consequences of malaria in pregnancy for both mother and baby.
- Conditions
- Malaria, Pregnancy, Malaria, Antepartum, Malaria (Uncomplicated)
- Trial name
- SAFIRE (NCT06962319)
- Testing
- dihydroartemisinin-piperaquine (DP), Pyronaridine-artesunate (PA), Artemether-lumefantrine
- Where
- 3 sites in Burkina Faso, Kenya and 1 more
- Volunteers
- 1,510 people
- Sponsor
- Liverpool School of Tropical Medicine
Malaria
Malaria Prevalence Around Maferinyah, Guinea
Background: Many women in Sub-Saharan Africa get malaria while they are pregnant. Plasmodium falciparum is a parasite that can cause malaria. Placental malaria (PM) caused by P.
- Trial name
- NCT04105855
- Where
- Guinea
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Pregnancy Malaria
A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV
More than 3 billion people worldwide are at risk of acquiring malaria and pregnant women living with HIV in Africa are at particular risk.
- Conditions
- HIV, Pregnancy Malaria, Sexually Transmitted Infection
- Trial name
- PREMISE (NCT03431168)
- Testing
- Azithromycin/TMPS
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
Malaria
Prevention of P. Vivax Malaria During Pregnancy in Bolivia
The purpose of this study is to determine which, between weekly prophylaxis or malaria attack treatment, both by chloroquine, is the most appropriate way to protect women and foetus from P.
- Trial name
- NCT00290420
- Testing
- Chloroquine profilaxis
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Malaria
Navrongo Drug Options for IPT in Pregnancy Trial
In areas of stable transmission, pregnant women, especially during the first and second pregnancies, have an increased susceptibility to Plasmodium falciparum malaria, malaria-related anaemia and an increased risk of having low…
- Trial name
- NCT00146783
- Testing
- Sulphadoxine-pyrimethamine, Sulphadoxine-pyrimethamine, amodiaquine
- Where
- Ghana
- Volunteers
- 3,642 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria, Pregnant
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
Randomized controlled single blind prospective comparative study
- Conditions
- Malaria, Pregnant, HIV
- Trial name
- NCT02527005
- Testing
- Sulphadoxine-pyrimethamine, Azithromycin
- Where
- Nigeria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Ibadan