Clinical trials: Pregnancy Outcomes
Exposure to Environmental Pollution
Impact of Exposure to Environmental Pollutants on Birth Outcomes in an Israeli Cohort
Objectives and hypothesis The scale and diversity of chemicals in worldwide use today is vast. Many of these chemicals are released into the environment where they are found in air, water, soil, house dust, and in the food…
- Trial name
- NCT03084445
- Where
- 3 sites in Israel
- Volunteers
- 2,394 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Pregnancy
Idealizing Pregnancy Outcome With Single Blastocyst Transfer in a FET Cycle
Single embryo transfer (SET) has been advocated as a means of reducing the risk of multiple pregnancies, but has meant a reduction in pregnancy risk per embryo transfer.
- Trial name
- NCT01987856
- Testing
- Blastocyst morphology
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF
Covid19, Vertical Transmission of Infectious Disease
Clinical Outcomes of Newborns Born to Pregnant Women With and Without COVID-19
A case-control trial was conducted to test the early postpartum period clinical outcomes of newborns born to pregnant women with and without COVID-19.
- Conditions
- Covid19, Vertical Transmission of Infectious Disease, Neonatal Infection, Pregnancy Related
- Trial name
- NCT04883801
- Testing
- Reviewed clinical records and laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Substance Use
Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns
This study recruits pregnant women and new mothers who are at risk of substance use concerns during pregnancy or delivery. These women are followed for 6 months and randomized into two groups; they may receive services as usual…
- Trial name
- NCT03735212
- Testing
- Enhanced Services
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Obesity, Gestational Diabetes
Impact of Diet and Exercise Activity on Pregnancy Outcomes
The general goal of the present study is to assess the impact of a community-based exercise and dietary intervention in pregnant women living in urban areas during and after their pregnancy on the reduction of the risks of both…
- Conditions
- Obesity, Gestational Diabetes, Type 2 Diabetes
- Trial name
- IDEA (NCT00486629)
- Testing
- Exercise and dietary education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Transthyretin Amyloidosis
The Eplontersen Pregnancy and Lactation Outcomes Study
The overall objective of this DPSS is to describe the occurrence of pregnancy and maternal complications, adverse effects on the developing fetus and neonate, and adverse effects on the infant associated with exposure to…
- Trial name
- EPPRO (NCT07205666)
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- AstraZeneca
Iodine Overload in Pregnancy
Registry Study for Pregnant Women With Iodine Overload
Pre-gestational performance of hysterosalpingography (HSG) using an oil-soluble iodinated contrast medium has been demonstrated to be the main cause of excessive iodine exposure for pregnant women.
- Trial name
- NCT03470597
- Testing
- dietary iodine restriction on subjects with iodine overload
- Volunteers
- 195 people
- Sponsor
- Peking Union Medical College Hospital
Acute Kidney Injury, Dialysis; Complications
Epidemiology of In-hospital Acute Kidney Injury
Retrospective observational study to investigate acute kidney injury (AKI) epidemiology and outcomes in patients hospitalized in University Hospital San Martino, Genova, Italy.
- Conditions
- Acute Kidney Injury, Dialysis; Complications, Chronic Kidney Diseases
- Trial name
- GENAKI (NCT05151003)
- Testing
- Data collection
- Where
- Italy
- Volunteers
- 60,000 people
- Sponsor
- Universita degli Studi di Genova
Ureteral Calculi
Study on 'The Use of Non-contrast Helical Computerized Tomogram in Predicting Treatment Outcomes of Upper Ureteric Stone by Extracorporeal Shock Wave Lithotripsy Using the Sonolith 4000+ Lithotripter'
The purpose of this research is to assess the role of non-contrast helical computerized tomogram in predicting the treatment outcome of upper ureteric stone by extracorporeal shock wave lithotripsy (ESWL).
- Trial name
- NCT00517205
- Testing
- Non-contrast helical computerized tomogram (NCHCT)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hospital Authority, Hong Kong
Delivery, Obstetric
Acupuncture for Promotion of Timely Delivery
The purpose of this study of 100 pregnant women is to determine if acupuncture using real needles that puncture the skin, starting at thirty seven weeks three days estimated gestational age (EGA), will increase the percentage of…
- Trial name
- NCT00379327
- Testing
- Acupuncture, Non-puncturing Acupuncture Needle
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- University of Pennsylvania
Preeclampsia, Hypertensive Disorder of Pregnancy
Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy
The present study is a single-centre prospective study that will enrol pregnant women during their first trimester of pregnancy (11+0 - 13+6 weeks of gestation).
- Trial name
- EDIPE (NCT05999851)
- Testing
- Arterial applanation tonometry, In vivo endothelial glycocalyx measurement, Serum markers of angiogenesis and endothelial dysfunction
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Transplant, Cardiovascular Disease
Randomized Trial of SGLT2i in Heart Transplant Recipients
Heart transplant (HTx) is an established therapy for advanced heart disease that restores quality of life and improves survival.
- Conditions
- Heart Transplant, Cardiovascular Disease, Kidney Disease
- Trial name
- NCT06625073
- Testing
- Empagliflozin
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
HPV-Related Carcinoma, Uterine Cervical Cancer
Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes
After definitive radiotherapy (RT) treatment (with or without chemotherapy), cervical and anal canal neoplasms frequently exhibit disease persistence or recurrence.
- Conditions
- HPV-Related Carcinoma, Uterine Cervical Cancer, Anal Canal Cancer, HPV-Related Anal Squamous Cell Carcinoma
- Trial name
- ANA (NCT06640283)
- Testing
- ctDNA test, Pembrolizumab
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Preeclampsia, Gestational Diabetes
Exercise and Pregnancy: Randomized Clinical Trial
The effects of physical exercise on pregnancy remain to be elucidated. A randomized controlled trial will be conducted to study the impact of exercise on maternal and perinatal outcomes.
- Trial name
- NCT00641550
- Testing
- Physical exercise
- Where
- 2 sites in Brazil
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual da Paraiba
Infertility, Infertility, Female
GnRH Agonist at Embryo Transfer: IVF Outcomes
In ART (assisted reproductive technology) cycles, embryos are transferred to a woman's uterus after in-vitro fertilization (IVF) in a laboratory.
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- GRAET (NCT03544073)
- Testing
- Saline Solution for Injection, Leuprolide Acetate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Cardiovascular Diseases, Kidney Diseases
HeAlth-data Register sTudies of Risk and Outcomes in Cardiac Surgery
The overall project aim is to study risk and outcomes following cardiac surgery by cross-linking high-quality national Swedish health-data registers for population-based investigations of individual level clinically relevant…
- Conditions
- Cardiovascular Diseases, Kidney Diseases, Depression, Diabetes Mellitus
- Trial name
- HARTROCS (NCT02276950)
- Testing
- Coronary artery bypass surgery, Heart valve surgery
- Volunteers
- 150,000 people
- Sponsor
- Ulrik Sartipy, MD, PhD
Endometriosis, Endometriosis (Diagnosis)
Deep Endometriosis Affecting the Urogenital Tract: Long-term Outcomes and Impact on Renal Function
Endometriosis is a chronic estrogen-dependent disease characterized by the presence and growth of endometrium-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Urinary Tract Diseases
- Trial name
- RENDO (NCT07776574)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Charles University, Czech Republic
Gestational Diabetes Mellitus in Pregnancy
Impact of Oral Probiotic Blend on Pregnancy Outcome
The aim of this study is, to investigate the effect of oral intake of Lactobacillus rhamnosus GG (ATCC 53103), Lactobacillus crispatus Lbv88, Lactobacillus rhamnosus Lbv96, Lactobacillus jensenii Lbv116 Lactobacillus gasseri…
- Trial name
- NCT04009889
- Testing
- capsule containing a probiotic blend of 5 different Lactobacilli, capsule containing Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, but no probiotics.
- Where
- Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- i-Health, Inc.
Placenta Accreta
Placenta Accreta Spectrum Topographic Classification
The present study is a prospective multicenter study consisting of a cohort of patients with prenatal or intraoperative diagnosis of PAS, evaluating the clinical outcomes of the group of patients found in each category of the…
- Trial name
- NCT05922397
- Where
- Colombia
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
Chronic Kidney Disease
Association of Diuretics With Change in Extracellular Volume, Natriuretic Peptides, Symptoms, and Cardiovascular Outcomes in CKD
Almost 15% of Americans have chronic kidney disease (CKD), with an even higher rate in Veterans due to common risk factors such as high blood pressure and diabetes.
- Trial name
- DOCK (NCT04192110)
- Testing
- Diuretic initiation or augmentation
- Where
- United States
- Sponsor
- VA Office of Research and Development