Clinical trials: Pregnancy Rate IVF
IVF
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
- Trial name
- NCT05951413
- Testing
- Sildenafil Citrate, estradiol
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Ovarian Stimulation
Antagonist/Letrozole in Poor Responders
Failure to respond to controlled ovarian hyperstimulation (COH) is still a major concern in assisted reproduction and there is no consensus on the ovarian stimulation choice regime for poor responders.
- Trial name
- NCT00823004
- Testing
- letrozole, oral contraceptive (Marvelone), GnRH agonist (buserelin)
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Follicle Size, Embryologic Parameters
Effect of Duration and Follicle Diameter During Oocyte Pick up on Embryological Parameters
Investigators aim to investigate if the time spent for smaller follicles worth to deal with. The difference between follicle groups are recorded for embryological parameters.
- Conditions
- Follicle Size, Embryologic Parameters, Duration
- Trial name
- NCT05666401
- Testing
- follicle diameter and duration of procedure
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 291 people
- Sponsor
- Eurofertil IVF Health Center
Infertility
The Effects of Intrauterine Infusion of hCG at the Time of Embryo Transfer
The purpose of this study is to determine whether intrauterine hCG can improve the implantation rate and clinical pregnancy rate after embryo transfer in IVF/ICSI cycle.
- Trial name
- NCT02668965
- Testing
- Intrauterine hCG (pregnyl)
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Complications Associated With Artificial Fertilization, Placenta; Implantation
Effect of Assisted Hatching on Vitrified Embryo Transfer Clinical Outcome
The objective of study is to assess the possible impact of assisted hatching on the implantation, pregnancy rate and delivery rate after transfer of vitrified-warmed human embryos.
- Conditions
- Complications Associated With Artificial Fertilization, Placenta; Implantation, Pregnancy
- Trial name
- VitHatSZMC (NCT02124291)
- Testing
- Mechanical Assisted Hatching
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Shaare Zedek Medical Center
Infertility
Endometrial Local Injury and Implantation Failure
The purpose of this study is to evaluate the influence of endometrial biopsy on increasing implantation rate in patients with recurrent implantation failures, 93 women with at least two implantation failures were evaluated.
- Trial name
- NCT00837733
- Testing
- Endometrial biopsy
- Where
- Iran
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility
Low-dose GH Supplementation Increases Clinical Pregnancy Rate
The objective of this study is to assess whether a low dose of GH supplementation (0.5 IU/day) increases clinical pregnancy rates in women with a history of POR who failed to become pregnant in two previous IVF cycles.
- Trial name
- NCT02359695
- Testing
- Growth Hormone
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Centro de Infertilidad y Reproducción Humana
Pregnancy Complication
Vitamin D During In Vitro Fertilisation (IVF) - A Prospective Randomized Trial
During IVF treatment women will be randomized into supplementation with a high or a low dose of Vitamin D Main outcome Laboratory pregnancy, live pregnancy at 12 weeks, Baby take home rate, OHSS Secondary outcome: 1.
- Trial name
- Delivery (NCT01019785)
- Testing
- Ergocalciferol
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Karolinska University Hospital
Infertility, Female
Efficacy and Safety of Gushen Antai Pill on Ongoing Pregnancy Rate in Women With Normal Ovarian Reserve Undergoing IVF-ET
The purpose of this study is to investigate whether oral Gushen Antai pills supplementation for luteal phase support will improve ongoing pregnancy rate in women with normal ovarian reserve in fresh embryo transfer cycles.
- Trial name
- GSATP-FreET (NCT04872660)
- Testing
- Gushen Antai Pill
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shandong University of Traditional Chinese Medicine
Pregnancy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing Embryo Transfer
The present study is designed to test the hypothesis that acupuncture, before and after embryo transfer, significantly improves pregnancy rates, compared to embryo transfer with sham acupuncture and no acupuncture at all.
- Trial name
- AcuIVF (NCT00722462)
- Testing
- Active acupuncture
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Infertility
Effects of Seminal Plasma on Pregnancy Rate With IVF
All couples planned for IVF will be asked to participate. After information and received informed consent they will be randomized into two groups.
- Trial name
- SENAVA (NCT02716753)
- Testing
- seminal plasma, Physiological NaCL solution
- Where
- Sweden
- Volunteers
- 1,600 people
- Sponsor
- Ostergotland County Council, Sweden
Acupuncture, Female Infertility
Acupuncture in the Freeze-all IVF Cycle
In the early stage, our team found that Acupuncture intervention in freeze-all IVF cycles can improve the clinical pregnancy rate.
- Trial name
- NCT04931355
- Testing
- Acupuncture, Western medicine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University Third Hospital
Female Infertility
Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders
In the present study we examined the effect of addition of CC to a low dose gonadotropin (150 IU/day) / GnRH antagonist protocol in comparison to a high gonadotropin dose (300 IU/day) regiment (short protocol) in women with poor…
- Trial name
- NCT06778733
- Testing
- Clomiphane citrate, recombinant human Follicle-Stimulating Hormone (r-FSH-alfa)
- Where
- 2 sites in Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Athens
Pregnancy, Ovarian
The Number of Blastocysts Formed in the Outcome of Freeze All Strategy: COMFFETI Trial, Cumulative Delivery Rate
A prospective study of the blastulation rate in the outcome of the Freeze all strategy
- Trial name
- NCT03463278
- Testing
- Pregnancy Rate
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Infertile Women Undergoing IVF or ICSI
Benefit of Ethanol Sclerotherapy of Endometriomas Before Ovarian Stimulation on Pregnancy Rates in IVF/ICSI
Evaluation of progressive pregnancy rates (with an embryo with cardiac activity at 12 weeks), on a first attempt at IVF/ICSI (fresh and frozen embryo transfers) following the discovery of one or two endometrioma(s) of 30 to 80…
- Trial name
- SCLERENDO (NCT06878053)
- Testing
- ethanol sclerotherapy
- Volunteers
- 174 people
- Sponsor
- Poissy-Saint Germain Hospital
Ovarian Stimulation
Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment
The aim of this study was to evaluate the effect of dehydroepiandrosterone supplementation on in vitro fertilization performance and outcome among poor-responder patient.
- Trial name
- NCT01145144
- Testing
- dehydroepiandrosterone crystalline fine powder
- Where
- 2 sites in Israel
- Sponsor
- Meir Medical Center
Infertility
A Phase IV, Prospective, Observational, Open Label, Single Centre Cohort Trial to be Conducted in Norway During One Year to Assess the Cumulative Pregnancy Rate in a New Series of In-vitro Fertilization (IVF) Treatment Cycles Following Three or More Previous IVF Treatment Cycles Without Live Birth
The primary objective of this observational study is to assess the cumulative rate of ongoing pregnancy at 10 ±2 weeks after hCG administration in a new series of IVF-treatment cycles in a total of 176 subjects, who have…
- Trial name
- NCT01071148
- Where
- Norway
- Volunteers
- 166 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Investigative Techniques, Reproductive Techniques
Does Letrozole Improve Pregnancy Outcome in Fresh Embryo Transfer IVF/ICSI Cycle?
Letrozole (Femara), is an aromatase inhibitor which is used in the treatment of hormonally-responsive breast cancer after surgery.
- Conditions
- Investigative Techniques, Reproductive Techniques, Reproductive Techniques, Assisted
- Trial name
- IVF/ICSI (NCT03901170)
- Testing
- Letrozole 2.5mg
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Ivf, Frozen Embryo Transfer (FET)
Comparison of Pregnancy Rates in Modified Natural Frozen Embryo Transfer (FET) Cycle After Luteal Support with GnRH Agonist Versus Progesterone
Background: The capability to transfer frozen embryos reduces embryo loss following in vitro fertilization (IVF) and results in higher pregnancy rates compared to a single IVF cycle.
- Trial name
- NCT06870266
- Testing
- Nafarelin nasal spray, Utrogestan®
- Volunteers
- 150 people
- Sponsor
- Shaare Zedek Medical Center
Human Embryo Cryopreservation
Comparison Between Three Freezing Protocols to Preserve Human Embryos
This randomized study compares three different freezing methods to store human in vitro fertilization (IVF) embryos: vitrification with two commercial kits or slow freezing.
- Trial name
- NCT00910390
- Testing
- Slow freezing, VIT-Irvine, Vit-Vitrolife
- Where
- Belgium
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital