Clinical trials: Pregnancy Termination
Habitual Abortion
Use of G-CSF for the Treatment of Unexplained Recurrent Miscarriage
In order to investigate the effectiveness of G-CSF in preventing embryo demise, the investigators administered this cytokine to women with recurrent miscarriage in a randomized controlled study compared to women treated with…
- Trial name
- NCT00772122
- Testing
- G-CSF, saline solution
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Florence
Abortion
Surgical Evacuation of Abortion Under Ultrasonographic Guide
Abortion is considered the most common cause of fetal demise all over the world. The majority of cases occur in the first trimester.
- Trial name
- NCT02580175
- Testing
- Blinded evacuation, Evacuation under ultrasound guidance
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Abortion in First Trimester
Pharmacist Provision of Medication Abortion
This will be a pilot study among two pharmacists providing start to finish medication abortions to 10 patients utilizing a previously created toolkit.
- Trial name
- NCT04956731
- Testing
- Pharmacist Provision of Medication Abortion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Threatened Abortion, Progesterone Resistance
Progesterone Supplementation in Threatened Abortion
To decide whether progesterone supplementation in threatened abortion is a sound practice.
- Trial name
- Prothreat (NCT03930212)
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Tanta University
Mutation
C677T Methylenetetrahydrofolate Reductase Mutation
To investigate the effect of anticoagulant treatment on pregnancy outcomes in patients with previous recurrent miscarriages (RM) who carry a methylenetetrahydrofolate reductase (MTHFR) gene mutation.
- Trial name
- C677T (NCT05864937)
- Testing
- infertily evaluation
- Where
- France
- Volunteers
- 363 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Medical Abortion Counselling
Telemedicin Counselling for Medical Abortion
The guidance on Safe abortion technology by the World Health Organization (WHO 2012) suggests the evaluation of internet provision and telemedicine, as further alternative service delivery channels of safe abortion, as a subject…
- Trial name
- NCT03461653
- Testing
- Telemedicine counselling
- Where
- Sweden
- Volunteers
- 1,598 people
- Sponsor
- Karolinska Institutet
Unintended Pregnancy, Undesired Pregnancy
Attitudes and Decision-making After Pregnancy Testing Study
The ADAPT Study is a longitudinal observational cohort study examining women's pregnancy preferences, pregnancy decision-making processes, and the effects of less preferred (commonly called "unintended") pregnancy on women's…
- Trial name
- ADAPT (NCT03888404)
- Testing
- Pregnancy preferences (Aim 1), Sociocultural environment (Aim 2), Pregnancy preferences (Aim 3a)
- Where
- United States
- Volunteers
- 2,015 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Other Abortion, Spontaneous Abortion
Gabapentin as an Adjunct to Perioperative Pain Management Regimens for Uterine Aspiration
This is a randomized controlled double-blind placebo-controlled trial evaluating the impact of gabapentin given preoperatively on perioperative pain scores for women receiving uterine aspiration between 6 and 14+6 weeks…
- Trial name
- GABA (NCT02725710)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Duke University
Abortion in First Trimester
Choice of Modality of Follow up for Medication Abortion
This study will assess the impact of providing medication abortion-seeking clients a choice for follow-up in practice. Clients presenting at or less than 63 days pregnant (based on last menstrual period) at the study site for…
- Trial name
- NCT04056637
- Testing
- Choice of follow-up option, Multi-level pregnancy test
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
Infertility and Miscarriage
A Multicenter, Prospective, Randomized, Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on the Natural Pregnancy Outcomes in Patients With Non-recurrent Spontaneous Abortion
The study aims to compare the effects of transcervical resection of septa (TCRS) and expectant management on the natural pregnancy outcomes of patients with septate uterus without recurrent abortion, also covering the treatment…
- Trial name
- NCT07039097
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 418 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pregnancy Complications
Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion
Induced abortion is a common method to terminate pregnancy, but during the operation, it is necessary to dilate the cervix and aspirate the uterine cavity.
- Trial name
- NCT06546397
- Testing
- 17β-estradiol/dydrogesterone tablets
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Abortion, Missed
Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases
Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of…
- Trial name
- NCT03767179
- Testing
- study
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Threatened Abortion
Corpus Luteum and Uterine Artery Doppler With Serum P and CA125 in Threatened Abortion
The purpose of this study is to determine whether assessing color doppler of corpus luteum and uterine artery is useful in predicting patients who will complete pregnancy.
- Trial name
- CLCA125 (NCT02420769)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Nesreen Abdel Fattah Abdullah Shehata
Medical Abortion
Acceptability and Feasibility of Medical Abortion in Singapore
To test the hypothesis that a regimen of 200 mg oral mifepristone, with the option of home administration, followed by 800 μg buccal misoprostol 24 hours later for abortion through 70 days LMP will be feasible and acceptable in…
- Trial name
- NCT02985229
- Testing
- Mifepristone, Misoprostol
- Where
- 2 sites in Singapore
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Contraception
Evaluation of Values Clarification and Attitude Transformation Workshops on Abortion and Family Planning Service Provision and Client Experience
Stigma around abortion and other reproductive health care is pervasive in most contexts and has been documented to have implications for the quality of care.
- Trial name
- NCT04181021
- Testing
- Values Clarification and Attitudes Transformation (VCAT) Workshop
- Where
- Ethiopia
- Volunteers
- 217 people
- Sponsor
- Ibis Reproductive Health
Miscarriage, Missed Abortion
Letrozole Pretreatment With Misoprostol fInduction of Abortion In First-Trimester Missed Miscarriage
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
- Trial name
- NCT03628625
- Testing
- Letrozole 2.5mg, Misoprostol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Adenomyosis, Infertility
Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment
Rationale: A rising number of adenomyosis cases are being diagnosed in women in the age group of 30 to 40 years. This is due to a combination of better diagnostic imaging techniques and a higher number of women delaying the…
- Conditions
- Adenomyosis, Infertility, ART, Pregnancy Loss
- Trial name
- AdAPT-ART (NCT05418140)
- Testing
- Ultrasound diagnosis of adenomyosis
- Where
- 9 sites in United Kingdom
- Volunteers
- 828 people
- Sponsor
- CARE Fertility UK
Menstrual Cycles, Conception
Factors Influencing Fertility or Pregnancy Health
Background: The North Carolina Early Pregnancy Study (EPS) was held from 1982 to 1986. Women who were trying to get pregnant took part in the study. They collected urine samples. They kept diaries. They filled out surveys.
- Conditions
- Menstrual Cycles, Conception, Early Pregnancy Loss, Pregnancy Outcomes
- Trial name
- NCT04595760
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Abnormal Uteroplacental Circulation
Study on Doppler Ultrasound Measurement of Changes in Uterine Artery Blood Flow in Normal First Trimester Pregnancies and Its Prediction on Abortion
Objective:To explore the study of Doppler ultrasound in first trimester pregnancies to measure the change of uterine artery blood flow in normal pregnancies and the prediction on abortion, which provides a certain reference for…
- Trial name
- NCT06043804
- Testing
- Doppler ultrasound measurement of changes in uterine artery blood flow
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Contraception
Continuation of Subcutaneous and Intramuscular Depot Medroxyprogesterone Acetate in Post-abortion Patients
Multiple prior studies have compared self-administered Subcutaneous Depot Medroxyprogesterone Acetate(DMPA-SC) to both provider-administered DMPA-SC and Intramuscular Depot Medroxyprogesterone Acetate (DMPA-IM) and found that…
- Trial name
- NCT05505435
- Testing
- Depot-Medroxyprogestereone Acetate
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Northwestern University