Clinical trials: Pregnancy Termination
Pregnancy Termination, Catheter
Foley Catheter vs Double-balloon Catheter
The efficiency of double-balloon and Foley catheters in the second trimester medical termination of pregnancies will be compared.
- Trial name
- NCT03521674
- Testing
- pregnancy termination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain
Pain and Medical Abortion Among Teenaged Women Compared to Adult Women
In this two-parted study the need and sufficiency of analgesics and experienced pain is compared between teen-aged and adult women undergoing medical termination of pregnancy (MToP)in early pregnancy (under 9weeks of gestation).
- Trial name
- NCT02678897
- Testing
- Oxynorm on-demand, Oxynorm via PCA
- Where
- 2 sites in Finland
- Volunteers
- 242 people
- Sponsor
- Helsinki University Central Hospital
Abortion Early
Dry vs Wet Misoprostol for Cervical Dilation in First Trimester Abortion
This study aims to verify whether the moisture of 400 µg of misoprostol pre uterine evacuation increases the dilatation of uterine cervix compared to dry misoprostol
- Trial name
- MisoWet (NCT02522078)
- Testing
- dry misoprostol, wet misoprostol
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pregnant Women Less Than 14 Weeks of Gestation
Accuracy of eDiagEPU, a Medical Computerized Tool for EPU
In a recently published study, a poor knowledge of guidelines in the field of early pregnancy was observed in France, Belgium and Switzerland.
- Trial name
- eDiagEPU (NCT03993015)
- Testing
- Help to diagnosis software
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Complete Miscarriage
Use of Letrozole Pretreatment With Misoprostol for First-Trimester Medical Abortion
The purpose of this study is to compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
- Trial name
- NCT02401425
- Testing
- Letrozole, Misoprostol
- Where
- Egypt
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Recurrent Pregnancy Loss, Fetal Demise
Pharmacokinetics of Low Molecular Weight and Unfractionated Heparin in Pregnancy
To determine, through pharmacokinetic parameters, the ideal dosing protocol for dalteparin (a low molecular weight heparin) and unfractionated heparin for women desiring pregnancy who have evidence of an acquired (specifically…
- Conditions
- Recurrent Pregnancy Loss, Fetal Demise, Abortion, Habitual, Antiphospholipid Antibodies
- Trial name
- NCT00721591
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Recurrent Miscarriage, Antiphospholipid Syndrome
Timing of Initiation of LMWH Administration in Pregnant Women With APS
Evaluation of the effect of altering the timing of initiation of low molecular weight heparin (LMWH) administration on the pregnancy outcomes in women with antiphospholipid syndrome (APS)
- Trial name
- NCT02326051
- Testing
- Enoxaparin
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Abdelhafez
Abortion Early
MA-ASAP at Independent Abortion Clinics: A Demonstration Project
In this study, the investigators propose to conduct a parallel study to MA-ASAP (ClinicalTrials.gov Identifier: NCT05278780) at an independent clinic.
- Trial name
- NCT05781061
- Testing
- Screening for Eligibility
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pain Management, Anti-Inflammatory Agents, Non-Steroidal
Effectiveness of Anti-Inflammatory Drugs for Preventing Pain Versus Treating Pain During Medical Abortion From 13 to 22 Weeks at Hung Vuong Hospital
The goal of this clinical trial is to assess the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for prophylactic pain relief compared to on-demand pain relief during medical abortion for pregnancies between 13…
- Conditions
- Pain Management, Anti-Inflammatory Agents, Non-Steroidal, Abortion, Spontaneous
- Trial name
- NCT06696573
- Testing
- Prophylactic NSAID Administration, On-Demand NSAID Administration
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Le Thi Kieu Trang
Abortion Rate
Post Abortion IUD & Recurrent Abortion 2001-2004
It has been shown that the immediate insertion of intrauterine devices (IUDs) post-abortion prevents repeat abortions. The researchers hypothesize that providing free IUDs post-abortion will be associated with a lower rate of…
- Trial name
- NCT00965770
- Testing
- Intrauterine device (IUD)
- Where
- Canada
- Volunteers
- 1,101 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Termination of Pregnancy
Exploring a Patient-centered Approach to Mifepristone Administration in Medical Abortion
This study will test ways to give women more options and flexibility when they are ending their unwanted pregnancies. The investigators will look at uptake and acceptability of using mifepristone outside of the clinic for…
- Trial name
- NCT01811056
- Testing
- Mifepristone
- Where
- 3 sites in United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Retained Products After Miscarriage
The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC
Pregnancy tissue can be found remaining in the womb in up to 20% of women following a miscarriage. These "retained products of conception" (RPOC), which are diagnosed by transvaginal ultrasound, can cause prolonged bleeding…
- Trial name
- HYMMN (NCT04751500)
- Testing
- Outpatient hysteroscopy, Expectant management, Medical management
- Where
- United Kingdom
- Volunteers
- 149 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Pregnancy
Better Contraceptive Choices: Immediate or Delayed Insertion of IUC After Second Trimester Abortion
Hypothesis Intrauterine contraception placed immediately after a second trimester abortion will result in fewer pregnancies than current standard practice of intended placement at 4 weeks post-abortion.
- Trial name
- NCT00877344
- Testing
- Immediate insertion, Interval insertion
- Where
- 3 sites in Canada
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Early Pregnancy, Early Pregnancy Loss
EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions
EARLY-PREG is an open-cohort clinical study with a preconception, longitudinal, bidirectional and counterfactual design. The aim of this cohort is to investigate the proteomic signatures of maternal-embryonic communication by…
- Conditions
- Early Pregnancy, Early Pregnancy Loss, Childbirth, Healthy
- Trial name
- EARLY-PREG (NCT07358026)
- Testing
- EMBRYO EXPOSURE
- Where
- Chile
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- MELISA Institute Genomics & Proteomics Research SpA
Blood Loss, Anesthesia
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures
Sevoflurane is an FDA-approved anesthetic drug commonly used for anesthesia during second trimester abortion procedures. It has a few advantages, including ease of use by the anesthesia provider.
- Trial name
- NCT01048658
- Testing
- Sevoflurane, No Sevoflurane
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy Termination
Travelling for Rights
This will be a retrospective cohort study comparing women obtaining an abortion in New Mexico and living in Texas and women obtaining an abortion in New Mexico and living in New Mexico .
- Trial name
- TOR (NCT03258463)
- Testing
- Change in Texas Law
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- University of New Mexico
Pain, Medical Abortion
Methadone and Medication Abortion
Pain has been recognized to be the most common and predictable side effect of medication abortion, causing significant distress associated with the process.
- Trial name
- NCT04941443
- Testing
- Methadone Pill, Ibuprofen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Medical Center
Abortion, Missed
Vaginal Misoprostol In Management Of First Trimester Missed Abortion.
The world health organization defined abortion or miscarriage as : the expulsion or extraction from its mother of a fetus or an embryo weighting 500 grams or less ,or any other wise product of gestation of any weight irrespective…
- Trial name
- NCT03148314
- Testing
- vaginal misoprostol, buccal/sublingual misoprostol
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Medical Termination of Pregnancy
Efficacy of Mifepristone - Prostaglandin Analogue Combination in Medical Termination of Pregnancy Beyond 7 Weeks of Amenorrhea
This study is a non-interventional prospective, multicenter, longitudinal study conducted in France, among a representative sample of public and/or private birth control centers.
- Trial name
- NCT02614781
- Where
- France
- Volunteers
- 892 people
- Sponsor
- Nordic Pharma SAS