Clinical trials: Pregnancy Termination
Vaginal Infections, Bacterial Vaginosis
Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery
The purpose of this study is to determine whether screening of pregnant women with history of previous preterm delivery, once a week, for bacterial vaginosis using VA-SENSE, and treatment of positive women will reduce the risk of…
- Conditions
- Vaginal Infections, Bacterial Vaginosis, Late Miscarriage, Preterm Birth
- Trial name
- NCT01152528
- Testing
- VA-SENSE
- Where
- Israel
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Common Sense
Abortion in First Trimester
Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion
This study evaluates dextromethorphan as a non-opioid adjunctive medication for pain control during medication abortion. This is double-blinded, four-arm randomized controlled trial enrolling 156 women over a period of 9-12…
- Trial name
- DexMab (NCT03480009)
- Testing
- Dextromethorphan Hydrobromide, Avicel PH101 (Microcrystalline Cellulose NF) for Compounding, Oxycodone
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Study Investigator-Sponsor
Abortion, Induced
Transvaginal Versus Transabdominal Digoxin Prior to Second-trimester Abortion
Current practice for the provision of late second trimester abortion (dilation and evacuation, or D\&E) often involves the administration of digoxin into the fetal compartment to induce fetal demise prior to the procedure.
- Trial name
- NCT02277249
- Testing
- Digoxin (transvaginal administration), Digoxin (transabdominal administration)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Care in Women With History of Recurrent Miscarriage
Nursing Counseling on Stress and Depression for Women With Recurrent Miscarriage
Recurrent miscarriage is a frustrating event for couples. The purpose of this randomized, controlled trial was to examine the effectiveness of nursing counseling on sleep quality, depression, stress, and social support in women…
- Trial name
- NCT04361747
- Testing
- nursing counseling
- Volunteers
- 62 people
- Sponsor
- National Cheng-Kung University Hospital
Spontaneous Abortions, Infertility
Molecular Associations With Reproductive Failure
The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion.
- Trial name
- NCT00298116
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Recurrent Miscarriage
Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies
Recurrent miscarriage (RM) is traditionally defined as three or more consecutive miscarriages occurring before 20 weeks post-menstruation.
- Trial name
- LMWH-APAN (NCT01608347)
- Testing
- LMWH+Folic acid, Folic Acid
- Volunteers
- 228 people
- Sponsor
- Omar Mamdouh Shaaban
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Medical Abortion
De-Medicalizing Mifepristone Medical Abortion
This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and…
- Trial name
- NCT00120224
- Where
- 3 sites in United States
- Volunteers
- 4,410 people
- Sponsor
- Gynuity Health Projects
Contraception, Abortion
Understanding Women's Contraceptive Expectations at the Time of a First Trimester Surgical Abortion
The investigators will conduct a voluntary anonymous survey at four separate Sacramento area family planning clinics. The investigators will ask the staff at each facility to offer a survey to all women 18 and older presenting to…
- Trial name
- NCT01807715
- Testing
- survey
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pain
Refining Paracervical Block Techniques for Pain Control in First Trimester Surgical Abortion
The purpose of this study is to determine the level of pain women experience with a surgical abortion and the effect that varying paracervical block techniques might have on that pain.
- Trial name
- NCT01466491
- Testing
- Paracervical block technique with lidocaine
- Where
- 2 sites in United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Second Trimester Abortion
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater…
- Trial name
- NCT03407521
- Testing
- Misoprostol, isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion, Missed
Comparison of Single and Repeated Dose of Vaginal Misoprostol for the Treatment of Early Pregnancy Failure
A randomised controlled trial assessing the efficacy of single versus repeated dose of vaginal misoprostol for the treatment of early pregnancy failure.
- Trial name
- NCT02515604
- Testing
- Misoprostol
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Wolfson Medical Center
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Contraception
Bleeding Pattern Difference Between Levonorgestrel Intrauterine System (LNG-IUS) and Copper Intrauterine Devices (IUDs) Immediately Inserted After Abortion
To observe the bleeding patterns of post-abortion immediate insertion of IUS compared to Cu-IUD over the first 6 months.
- Trial name
- POST (NCT01958684)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028), Copper-IUD
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Bayer
Undifferentiated Connective Tissue Disease, Recurrent Pregnancy Loss
Immunosuppressant Regimens for Living Fetuses Study
Undifferentiated connective tissue diseases (UCTD) are known to increase the risk of pregnancy morbidities, including recurrent pregnancy loss.
- Trial name
- NCT03671174
- Testing
- Prednisone, Hydroxychloroquine, Aspirin
- Where
- China
- Volunteers
- 420 people
- Sponsor
- RenJi Hospital
Voluntary Termination of Pregnancy
Preoperative Ultrasound Evaluation of Gastric Contents in Voluntary Termination of Pregnancy During the First Trimester
This is an observational, prospective, monocentric, diagnostic study aiming to evaluate the diagnostic properties of the presence of nausea-vomiting in predicting the existence of gastric contents in preoperative surgical…
- Trial name
- ECHONAV (NCT06210308)
- Testing
- Data collection from gastric ultrasound
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Contraception
IUD Insertion Post First Trimester Abortion
The goal of this study is to provide better information about contraception to women having an abortion so that they are less likely to have another unintended unwanted pregnancy.
- Trial name
- NCT01174225
- Testing
- Flexi T 380(+) IUD, Nova T IUD
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Medical Abortion, Complete or Unspecified, Without Complication
Piloting Use of Multi-Level Pregnancy Tests in Remote Abortion Services
Serial use of urine multi-level pregnancy tests (MLPTs) has been shown to be a reliable and efficient strategy for excluding ongoing pregnancy after medical abortion at ≤ 63 days of gestation.
- Trial name
- NCT03207880
- Testing
- Multi-level pregnancy test
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center