Clinical trials: Pregnancy Termination
Missed Abortion
Oxytocin Effectiveness in First Trimester Dilatation and Curettage
The aim of this study is to investigate the impact of oxytocin on perioperative blood loss during the D\&C procedure, as well as to assess early and late complications associated with it's use.
- Trial name
- NCT06469203
- Testing
- Oxytocin, Sodium Chloride 0.9% Inj
- Volunteers
- 160 people
- Sponsor
- Assuta Ashdod Hospital
Infertility, Female
Immediate Ambulation Versus Short-time Bed Rest in Sub-fertile Women Undergoing Embryo Transfer
Bed rest after embryo transfer (ET) has been clinically advised without robust scientific evidence. In investigators' unit, post ET instructions are given immediately after ET to sub-fertile women while lying in bed.
- Trial name
- NCT05148624
- Testing
- embryo transfer
- Where
- United Arab Emirates
- Volunteers
- 156 people
- Sponsor
- Dubai Fertility Center
Threatened Miscarriage
Non-interventional Study of Therapy for Threatened Miscarriage
Study the efficacy and safety of therapy for threatened miscarriage with medicinal products Utrogestan (micronized progesterone), 200 mg capsules (Besins Healthcare SA, Belgium), and Duphaston (Dydrogesterone), 10 mg coated…
- Trial name
- NCT03309735
- Testing
- Micronized progesterone, Dydrogesterone
- Where
- 17 sites in Russia
- Volunteers
- 1,241 people
- Sponsor
- Besins Healthcare
Abnormal Vaginal Flora, Clindamycin Vs Metronidazole
Comparison Between Oral Clindamycin Vs Metronidazole for the Treatment of Abnormal Vaginal Flora in High Risk Pregnancies
Abnormal vaginal flora is a risk factor for preterm labor. Therefore, in high risk pregnancies for preterm labor the diagnosis and treatment of abnormal flora is indicated.
- Conditions
- Abnormal Vaginal Flora, Clindamycin Vs Metronidazole, High Risk Pregnancies for Preterm Labor
- Trial name
- NCT01722708
- Testing
- Clindamycin, Metronidazole
- Where
- 2 sites in Israel
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Antepartum Bleeding, Preterm Birth
Progesterone and Second Trimester Bleeding
Working hypothesis and aims: To investigate whether progesterone treatment affects the incidence of preterm labor compared to placebo, among women with 2nd trimester bleeding.
- Trial name
- NCT01269450
- Testing
- micronized progesterone 200 mg (Utrogestan)
- Where
- 3 sites in Israel
- Volunteers
- 128 people
- Sponsor
- HaEmek Medical Center, Israel
Early Pregnancy Bleeding, Abdominal Pain
Pelvic Examination in Pregnancy
This study is designed to determine whether the pelvic examination (including bimanual and speculum examination) is necessary in patients with first trimester vaginal bleeding/ lower abdominal pain when an intra-uterine pregnancy…
- Trial name
- PEP (NCT01570413)
- Testing
- No Pelvic Exam, Pelvic Examination
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Boston Medical Center
Pregnancy Related, Abortion
Determining Beta-hCG Levels in Patients Through Alternative Sample Types
This study is to determine if there is any quantifiable correlation between serum beta hCG and dried blood spot (DBS) beta hCG levels.
- Trial name
- NCT06178224
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Simple HealthKit
Abortion, Drug-Induced, Pharmacies
Evaluating an Intervention to Increase Use of Call Centre Support for Self-managed Medical Abortion
Self-management of medical abortion (MA) pills purchased from pharmacies is considered to be one of the reasons behind falling morbidity and mortality from unsafe abortion in recent years.
- Trial name
- NCT03248050
- Testing
- Pharmacy encouraged to promote call centre use to clients
- Volunteers
- 1,359 people, healthy volunteers welcome
- Sponsor
- Marie Stopes International
Missed Abortion
Letrozole Pretreatment With Misoprostol Induction of Abortion In First-Trimester Missed Miscarriage
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy among women with one or more previous cesarean deliveries.
- Trial name
- NCT04215835
- Testing
- letrozole then misoprostol
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pregnancy Related
Medication Abortion for Pregnancy of Unknown Location
The purpose of this study is to compare time to completed abortion between two protocols for patients seeking medication abortion - same-day start versus delay-for-diagnosis - in the setting of asymptomatic, low-risk, pregnancy…
- Trial name
- MAPUL (NCT04026789)
- Testing
- Same-day-start, Delay-for-diagnosis
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Abortion, Missed, Infertility Unexplained
Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure
The aim of this study is to verify the efficacy of in vitro induction of autologous decidual-like NK cells therapy for reproductive failure associated with uterine NK cells abnormalities.
- Conditions
- Abortion, Missed, Infertility Unexplained, Reproductive Disorder
- Trial name
- NCT07230574
- Testing
- NK cell perfusion group
- Volunteers
- 159 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Early Miscarriage
Identification of Histories of Pregnancy Termination, Particularly Early Miscarriage, in General Medical Records
Early miscarriage (EM) is defined as the spontaneous expulsion of an intrauterine pregnancy of less than 14 weeks' duration. Early miscarriage is a very common complication, affecting more than 10% of pregnancies.
- Trial name
- NCT07406776
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Medical; Abortion, Fetus
Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester Abortion
Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester abortion.
- Trial name
- NCT02694198
- Testing
- fetal fibronectin measurement
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Missed Abortion, Anembryonic Pregnancy
Ulipristal Acetate for Use in Early Pregnancy Loss
The investigators will study the feasibility of using 90mg ulipristal acetate, a selective progesterone receptor agonist, as an adjunct to 800mcg vaginal misoprostol for the medical management of early pregnancy loss.
- Conditions
- Missed Abortion, Anembryonic Pregnancy, Non-Viable Pregnancy
- Trial name
- NCT05216952
- Testing
- Ulipristal Acetate Tablets, Misoprostol Pill
- Where
- 4 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of North Carolina, Chapel Hill
Medical; Abortion, Fetus
Evaluation of Efficacy of Two Therapeutic Strategies for Cervical Maturation Before Medical Termination
Reducing the time patients spend in the labor and delivery room saves money and reduces patient discomfort as well and reducing complications.
- Trial name
- IMEGYN (NCT03194126)
- Testing
- Mifepristone + Misoprostol OR oxytocine + laminaria, Mifepristone + Misoprostol OR oxytocine
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Abortion in First Trimester
Auriculotherapy - Pain Management of Aspiration Abortion
Primary Objective: To assess whether usual care plus auricular acupressure with beads reduces subject-reported maximum pain during first trimester vacuum aspiration compared to usual care plus placebo.
- Trial name
- NCT03896022
- Testing
- Acupressure with Beads, Acupuncture with Needles
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Columbia University
Health Behavior
PAFP Provider Feedback Trial in Nepal
A six-month RCT conducted within 36 health centres throughout urban and rural Nepal. The purpose of the RCT is to test the effectiveness of a peer comparison intervention at increasing uptake of long-acting reversible…
- Trial name
- NCT03071029
- Testing
- Monthly PAFP rates displayed at clinics.
- Where
- 36 sites in Nepal
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Marie Stopes International
Unintended Pregnancy, Teen Births
The Contraceptive Choice Project
The purpose of this project is to remove barriers to obtaining contraceptive methods, including the most effective and expensive methods.
- Conditions
- Unintended Pregnancy, Teen Births, Abortion, Contraception
- Trial name
- NCT01986439
- Where
- United States
- Volunteers
- 9,256 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Medical Abortion
Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks
This study seeks to evaluate the efficacy, side effect profile and acceptability of a medical abortion regimen with mifepristone and two doses of 800 mcg misoprostol buccally at 71-77 and 78-84 days of gestation to further expand…
- Trial name
- NCT05119439
- Testing
- Mifepristone + 2 doses of misoprostol 800 mcg
- Where
- 6 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Early Pregnancy Loss, Abortion, Spontaneous
Surgical vs. Medical Abortion on Sexual Function After Early Pregnancy Loss
This study compares the medium-term effects of surgical and medical abortion on sexual function in women who have experienced early pregnancy loss (6-12 weeks gestation).
- Conditions
- Early Pregnancy Loss, Abortion, Spontaneous, Miscarriage, Pregnancy, Unwanted
- Trial name
- SF-EPL (NCT07646275)
- Testing
- mifepristone and misoprostol, Vacuum Aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Harran University