Clinical trials: Pregnancy Termination
Helicobacter Pylori Infection, Susceptibility to
Helicobacter Pylori Infection Among Women With Recurrent Abortion of Unknown Cause
Helicobacter pylori (H. pylori) infection affects approximately one half of the world population and it is more prevalent in developing countries. This microorganism colonizes the stomach.
- Trial name
- NCT07293169
- Testing
- H pylori eradication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Early Pregnancy
Comparison of the Effectiveness of Treatment With Mifepristone and Misoprostol at the Same Time Compared to the Administration of Drugs at a 48-hour Interval for Medical Abortion.
Medical termination of pregnancy is a common and safe alternative to surgical termination of pregnancy(8). The current protocol in the investigators unit includes oral administration of Mifepristone 600 mg and oral Misoprostol…
- Trial name
- NCT03440866
- Testing
- Administration of drugs concomitantly.
- Where
- Israel
- Volunteers
- 250 people
- Sponsor
- HaEmek Medical Center, Israel
Abortion Stigma
Measurement of Individual Level of Abortion Stigma Study
This study is a randomized controlled trial designed to measure abortion stigma related to the Pennsylvania Abortion Control Act.
- Trial name
- NCT02672605
- Testing
- Pennsylvania State Abortion Consent
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pennsylvania
Miscarriage
Medical Abortion With Single Daily Dose of Misoprostol
Medical abortion using multiple vs single daily dose of misoprostol in first trimester miscarriage.
- Trial name
- NCT03487354
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Recurrent Pregnancy Loss, Recurrent Miscarriages
Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent Miscarriage
Recurrent pregnancy loss (RPL), commonly referred to as recurrent miscarriage, affects approximately 1-2% of couples attempting to conceive.
- Trial name
- GEM (NCT07724405)
- Testing
- Recombinant G-CSF
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Fakih IVF Fertility Center
Infertility, Recurrent Pregnancy Loss
Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis
We propose to perform a clinical randomized trial to evaluate the effect of blastocyst biopsy and whole chromosome analysis by Next Generation Sequencing (NGS) in comparison to standard Assisted Reproductive Technologies (ART)…
- Trial name
- NCT01946945
- Testing
- Next Generation Sequencing after Blastocyst biopsy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Reprogenetics
Endometriosis, Miscarriage
Endometriosis and Risk of Miscarriage
The aim of this study is to compare the rate of miscarriage at first spontaneous pregnancy among women with endometriosis with the rate of miscarriage at first spontaneous pregnancy among women without endometriosis.
- Trial name
- NCT03354780
- Testing
- Survey on first pregnancy after endometriosis diagnosis, Survey on first pregnancy
- Volunteers
- 844 people
- Sponsor
- Endometriosis Treatment Italian Club
Pregnancy
First Trimester of Pregnancy: Impact of a History of Miscarriage on Women's Stress
Miscarriage is the spontaneous termination of pregnancy before 22 weeks of amenorrhea. The most frequent complication of pregnancy, it represents 10 to 25% of pregnancies and affects one in four women.
- Trial name
- Stress-FC (NCT04841486)
- Testing
- Data collection
- Where
- France
- Volunteers
- 93 people
- Sponsor
- Université de Reims Champagne-Ardenne
Abortion Early
The Relation of High Sensitivity C Reactive Protein and Total Leucocytic Count Levels in Threatened Abortion
to identify the relation between maternal serum high sensitivity C reactive protein and total and differential leucocytic count values in healthy pregnant women with threatened abortion and the outcome of pregnancy
- Trial name
- NCT05986357
- Testing
- maternal serum C reactive protein, total leucocytic count levels, differential leucocytic count levels
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Preterm Birth, Threatened Preterm Labor
Cervical Softening and the Prediction of Preterm Birth
Currently, transvaginal cervical length measurement is used to screen in asymptomatic pregnant women with a history of PTB. In symptomatic women, presenting with threatened PTB cervical length in combination with the fibronectin…
- Conditions
- Preterm Birth, Threatened Preterm Labor, Premature Birth, Premature Labor
- Trial name
- STIPP (NCT05477381)
- Testing
- Measurement of cervical stiffness by Pregnolia Device
- Where
- Netherlands
- Volunteers
- 390 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cervical Ripening
Misoprostol Versus Dilapan-S for Cervical Preparation
The purpose of this study is to compare the dilatory effect of 400 mcg of buccally administered misoprostol to one Dilapan-S rod placed 3-4 hours before abortion by dilation and evacuation in women who are 12 weeks 0 days to 15…
- Trial name
- NCT00835731
- Testing
- misoprostol, Dilapan-S, vitamin B-12
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Termination of Pregnancy (TOP)
Interest of Cervical Dilators in Second Trimester Termination of Pregnancy
The purpose of this study is to evaluate whether the use of cervical dilators for cervical ripening in case of second trimester medical termination of pregnancy (TOP) is effective to reduce duration of labor.
- Trial name
- DILATOP (NCT03194230)
- Testing
- With cervical dilatator
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Social Stigma, Pregnancy
A Pre and Post Test Intervention Design to Prevent Abortion and Contraceptive-use Stigma Among School Youths in Kenya
In many low-income countries, unsafe abortion is recognized as a leading cause of maternal morbidity and mortality. Social stigma surrounding abortion and contraceptive use plays a critical role in the social, medical, and legal…
- Conditions
- Social Stigma, Pregnancy, Contraception
- Trial name
- SAC (NCT03065842)
- Testing
- Abortion- and contraceptive-use stigma reduction program, Usual Standards
- Where
- Kenya
- Volunteers
- 1,207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Pregnancy Loss, Early, Major Depression
Effect of Participating in a Study of Causes of Pregnancy Loss on Mental Health Outcomes: A Target Trial Emulation Using the COPL Cohort and Danish National Registries
Pregnancy loss is the most common severe pregnancy complication and is associated with significant mental health sequelae, including depression and anxiety.
- Conditions
- Pregnancy Loss, Early, Major Depression, Anxiety, Stress (Psychology)
- Trial name
- NCT07684677
- Testing
- COPL participation
- Where
- Denmark
- Volunteers
- 30,000 people
- Sponsor
- Amager Hospital
Abortion
Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Women who are requesting pregnancy termination at 14-16 weeks, who would normally have osmotic dilator insertion the day before their procedure, would be asked if they wanted to participate.
- Trial name
- SAMi (NCT00986921)
- Testing
- mifepristone 200 mg, osmotic dilator insertion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Medical Abortion
Comparison of the Safety and Efficacy of Medical Abortion Provided by Physicians and Midlevel Providers in Nepal
The purpose of the study is to compare the safety, effectiveness, and acceptability of medical abortion provided by doctors and midlevel providers in a developing country where doctors are scarce, such as Nepal.
- Trial name
- NCT01186302
- Testing
- Type of provider
- Where
- Nepal
- Volunteers
- 1,104 people
- Sponsor
- World Health Organization
Abortion
Voluntary Interruption of Pregnancy on Women's Sexuality
The impact on sexuality has been less studied and there is no French study on this subject and the rare studies are contradictory.
- Trial name
- VTOPSimpact (NCT05688228)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 209 people
- Sponsor
- University Hospital, Bordeaux
Recurrent Abortion
Laparoscopic Transabdominal Cerclage: New Approach
A 5-mm non-absorbable Mersilene polyester suture, with adjacent partially straightened blunt needles, is introduced into the abdominal cavity through the 5-mm trocar.
- Trial name
- NCT02457377
- Testing
- laparoscopic cerclage
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ahmed Maged