Clinical trials: Pregnancy Termination
Health Behavior
PAFP Provider Feedback Trial in Nepal
A six-month RCT conducted within 36 health centres throughout urban and rural Nepal. The purpose of the RCT is to test the effectiveness of a peer comparison intervention at increasing uptake of long-acting reversible…
- Trial name
- NCT03071029
- Testing
- Monthly PAFP rates displayed at clinics.
- Where
- 36 sites in Nepal
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Marie Stopes International
Abortion
Surgical Evacuation of Abortion Under Ultrasonographic Guide
Abortion is considered the most common cause of fetal demise all over the world. The majority of cases occur in the first trimester.
- Trial name
- NCT02580175
- Testing
- Blinded evacuation, Evacuation under ultrasound guidance
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Abortion, Induced, Abortion, Incomplete
Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa
The primary purpose of this research is to develop strategies and interventions to mitigate the impact of conscientious objection on women's access to safe abortion care in Mexico and South Africa using a user-centered design…
- Trial name
- NCT04290832
- Testing
- CO Intervention
- Where
- 2 sites in Mexico, South Africa
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Ipas
Oral Health, Miscarriage
Is There an Interaction Between Recurrent Miscarriage and Dental Health
Oral infections can trigger the production of pro-inflammatory mediators that may be risk factors for miscarriage. The investigators investigated whether oral health care patterns that may promote or alleviate oral inflammation…
- Trial name
- NCT03577314
- Testing
- miscarriage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Pregnancy
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Ukraine and Uzbekistan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05028387
- Testing
- medical abortion
- Where
- 4 sites in Ukraine, Uzbekistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Covid19, Obstetric Complication
COVID-19 Infection and Fetal-neonatal Outcomes
COVID-19, the coronavirus responsible for the pandemic that began at the end of 2019 in China, spreads through respiratory droplets and direct contact.
- Conditions
- Covid19, Obstetric Complication, SARS-CoV Infection, Preterm Birth
- Trial name
- NCT04699578
- Testing
- Covid-19 positive
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- University of Campania Luigi Vanvitelli
Miscarriage, Frozen Embryo Transfer
Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients
The aim of the current study is to compare miscarriage rates (before 8 weeks) between a true natural cycle (awaiting spontaneous LH surge) and a hormone replacement therapy cycle prior to blastocyst transfer in preimplantation…
- Conditions
- Miscarriage, Frozen Embryo Transfer, Natural Cycle, Hormone Replacement Therapy Cycle
- Trial name
- NCT03976544
- Testing
- Estradiol Valerate, Micronized progesterone
- Where
- Belgium
- Volunteers
- 362 people
- Sponsor
- CRG UZ Brussel
Pre-Term, Cervical Insufficiency
Obstetric Outcome in Pregnancies Treated With Laparoscopic Cerclage
Preterm birth is a leading cause of neonatal mortality and morbidity. Cervical insufficiency is one factor implicated in the complex mechanisms involved in spontaneous preterm birth.
- Trial name
- NCT05863481
- Testing
- Laparoscopic cerclage placement
- Volunteers
- 185 people
- Sponsor
- University of Aarhus
Incomplete Abortion
Misoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.
It is estimated that 47,000 women die every year due to consequences of unsafe abortion globally. The majority of pregnancy related deaths occur in low income countries where induced abortion is restricted, unmet need for…
- Trial name
- NCT03622073
- Testing
- Misoprostol treatment by Midwife, Misoprostol treatment by Doctor
- Where
- 14 sites in Uganda
- Volunteers
- 1,191 people
- Sponsor
- Makerere University
Preterm Labor, Cervical Incompetence
Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening
The aim of this study is to Determine whether cerclage with vaginal progesterone will: 1. Reduce the overall spontaneous preterm birth rate. 2. Prolong pregnancy latency. 3. Improve neonatal outcome.
- Trial name
- NCT03837288
- Testing
- Cerclage
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion, Incomplete
Misoprostol for the Treatment of Incomplete Abortion
This randomized study will examine the efficacy, safety and acceptability of misoprostol for treatment of incomplete abortion. Women diagnosed with incomplete abortion will be randomized to receive one of the following regimens…
- Trial name
- NCT00670761
- Testing
- misoprostol, MVA
- Where
- 6 sites in Burkina Faso, Madagascar and 3 more
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion in First Trimester
Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion
A therapeutic abortion is one of the most common procedures performed in Canada, with approximately 100,000 occurring annually. 95% of induced abortions are done surgically, with just over two thirds of these procedures taking…
- Trial name
- NCT03751423
- Testing
- PO Morphine, IV Fentanyl, IV Ketamine
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Dr. Marie Eve Sophie Bussiere-Cote
Recurrent Abortion
the Insulin Resistance in Recurrent Miscarriage IN RECURRENT ABORTION
THE INSULIN RESISTANCE IN RECURRENT ABORTION
- Trial name
- NCT02088424
- Testing
- insulin resistance(fasting glucose/fasting insulin)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Abortion, First Trimester, Pain Management
Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion
The goal of this clinical trial is to learn whether use of a virtual reality (VR) headset showing a meditative nature video will help reduce pain and anxiety during a first trimester procedural abortion.
- Conditions
- Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction
- Trial name
- CALM-VR (NCT07288047)
- Testing
- VR headset, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Study Investigator
Abortion
Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of transdermal hormonal contraception (the patch) in post-abortion subjects can improve compliance and the…
- Trial name
- NCT00235547
- Testing
- timing of initiation of transdermal patch after an abortion
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autoimmune Thyroiditis, Recurrent Miscarriage
Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss
The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies.
- Trial name
- NCT05680376
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Zonguldak Bulent Ecevit University
Miscarriage, Early Pregnancy Loss
Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors
About 1 to 3% of women of childbearing age suffer repeated early spontaneous miscarriages (RCF) defined by at least 3 fetal losses before 14 weeks of gestation.
- Trial name
- FALCO (NCT05557201)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abortion
Evaluation of of a Prefixed 50% N2O- 50%O2 Mixture in Legal Abortion Under Local Analgesia
To evaluate effectiveness of a prefixed 50% N2O- 50%O2 mixture in legal abortion under paracervical block.
- Trial name
- NCT00769912
- Testing
- 50% N2O- 50%O2 mixture
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Threatened Miscarriage
Biochemical, 2D and 3D Ultrasonographic Predictors of Pregnancy Outcome in Women With Threatened Abortion
Three or two measurements (according to GA) using 2D and 3D ultrasound examinations will be done at initial assessment of the participants then after 1 to 2 weeks and at the end of the 12th week of gestation
- Trial name
- NCT06797557
- Testing
- 2D Ultrasound, 3D ultrasound
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Abortion in First Trimester, Pain, Procedural
Ketamine Versus Fentanyl for Surgical Abortions
Ketamine is commonly used for procedural sedation and analgesia. It is widely used for trauma cases in the emergency department and is considered a superior agent in the outpatient setting due to its lack of respiratory and…
- Conditions
- Abortion in First Trimester, Pain, Procedural, Opioid Use
- Trial name
- NCT04871425
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington