Clinical trials: Pregnancy Testing
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Incontinence, Urinary, Incontinence, Fecal
Testing the Protective and Caring Effect of a Water-in-oil Formulation in Patients Suffering From Urinary and/or Fecal Incontinence and Requiring Incontinence Care Products
The aim of this study is to test the protecting and caring effect of a protective balm on patients suffering from urinary and/or fecal incontinence and need incontinence care products.
- Trial name
- NCT06924502
- Testing
- Protective Balm
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Gestational Diabetes, Pregnancy
Oral Glucose Tolerance Testing After Gestational Diabetes
This is an observation study of women with gestational diabetes. Subjects recruited undergo immediate postpartum diabetic screening prior to discharge. Post-partum screening for overt diabetes is repeated 6-12 weeks postpartum.
- Conditions
- Gestational Diabetes, Pregnancy, Obesity
- Trial name
- NCT02082301
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- MetroHealth Medical Center
Advanced Solid Tumor
Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor
This research study is studying an investigational combination of drugs as a possible treatment for advanced solid tumors: melanoma, ovarian, renal, or colorectal cancer. The drugs involved in this study are: Pembrolizumab AMG386
- Trial name
- NCT03239145
- Testing
- Pembrolizumab, Trebananib
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Dana-Farber Cancer Institute
CIN, Cervix Cancer
HPV E6/E7 mRNA Versus HPV DNA as Triage for Cervical Cancer Screening
AIM: To develop and standardize a cost effective methodology or algorithm for mRNA E6/E7 for HPV genotypes 16, 18, 31, 33 and 45 as compared to commercially available assays which can be incorporated to triage excess false…
- Trial name
- PODBT (NCT02116920)
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Tata Memorial Hospital
Embryo Transfer
Feasibility and Acceptability of Using the Semi-quantitative Pregnancy Test in an Assisted Fertility Setting
Given the potential of semi-quantitative pregnancy tests as part of assisted fertility care, we would like to document the feasibility and acceptability of a semi-quantitative pregnancy test as an adjunct to or replacement of…
- Trial name
- NCT01846403
- Testing
- Semi-quantitative urine pregnancy test
- Where
- Vietnam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Down Syndrome, Patau Syndrome
Clinical Evaluation of the IONA Test for Non-invasive Pre Natal Screening in Twin Pregnancies
The purpose of this study is to evaluate the performance of the IONA® test which is a non-invasive prenatal test (NIPT) for Down's syndrome and other chromosomal abnormalities in twin pregnancies, from a maternal blood sample.
- Conditions
- Down Syndrome, Patau Syndrome, Edward's Syndrome
- Trial name
- TWIN (NCT03200041)
- Testing
- Blood sample
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Premaitha Health
Pregnancy
Clinical Investigation for the Preview® hCG Urine/Serum Combo Pregnancy Test
The objective of this study is to evaluate the agreement of the test device (Preview® hCG Urine/Serum Combo Pregnancy Test) with the predicate device, the QuickVue+ hCG Combo Test.
- Trial name
- Preview® hCG (NCT04207554)
- Testing
- Test Device-Strip Format, Test Device-Cassette Format, Predicate Device
- Where
- 6 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Guangzhou Wondfo Biotech Co., Ltd
Endometrial Cancer, DNA Methylation
Cervical Cytology DNA Methylation for Endometrial Cancer Screening
This study intends to conduct the "Real-world Study on Cervical Cytology Methylation Testing for Endometrial Cancer Screening" project through a multi-center real-world research approach.
- Conditions
- Endometrial Cancer, DNA Methylation, Cytology, Cancer Screening
- Trial name
- NCT07874529
- Testing
- CDO1 and CELF4 gene methylation
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- Lei Li
Pregnancy Related
Home Pregnancy Test Evaluation, Lay User Study
This study is a performance evaluation study to assess the performance of a home pregnancy test (HPT) in the hands of lay users by comparing their results, when used according to the Instructions for Use (IFU), to (a) the lay…
- Trial name
- NCT04372745
- Where
- United Kingdom
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Infertility, Female
Testing a New Self-help Intervention for Infertility Related Distress: a Pilot Study
This pilot study will test the effect of a 6-week self-help program in improving fertility-related quality of life as well as anxious and depressive symptoms, in women with infertility.
- Trial name
- NCT05103982
- Testing
- Coping with Infertility Program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Regina
Prenatal Education
The Effect of Mother's Anxiety, Fear and Prenatal Connection in the Prenatal Education Given to Pregnant Women Via Podcast During the Non-stress Test
This study was planned to determine the effect of prenatal education given via podcast to nulliparous pregnant women who applied to the Non-Stress Test Polyclinic of the University of Health Sciences, Istanbul Bagcilar Training…
- Trial name
- NCT06313723
- Testing
- Prenatal education management delivered via podcast
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- YASEMİN AYDIN KARTAL
Human Papillomavirus Infection
Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System
The purpose of this study is to provide data on the performance of the APTIMA HPV Assay using the TIGRIS System in detecting HPV types that may cause cervical cancer.
- Trial name
- NCT00973362
- Testing
- APTIMA HPV Assay, FDA-Approved HPV DNA Test
- Where
- 17 sites in United States
- Volunteers
- 12,896 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Carcinoma, Renal Cell
Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing
The purpose of this study is to determine the effect of a sunitinib administration schedule 2/1 (2 weeks of treatment followed by 1 week without) compared to a schedule 4/2 (4 weeks of treatment followed by 2 weeks without) on…
- Trial name
- ASSET (NCT03109015)
- Testing
- Sunitinib
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Malaria, Antepartum, Maternal Malaria During Pregnancy - Baby Not Yet Delivered
Community-based Screening and Treatment of Malaria in Pregnancy: a Cluster-randomized Trial
Malaria is a common disease in Africa and a major health problem. Pregnant women are also at risk of malaria. Malaria in pregnancy is life threatening to both the mother and the baby she is carrying.
- Conditions
- Malaria, Antepartum, Maternal Malaria During Pregnancy - Baby Not Yet Delivered, Small for Gestational Age (Disorder)
- Trial name
- COSMIC (NCT01941264)
- Testing
- community based screening and treatment
- Where
- 3 sites in Benin, Burkina Faso and 1 more
- Volunteers
- 4,265 people, healthy volunteers welcome
- Sponsor
- Royal Tropical Institute
Cervical Intraepithelial Neoplasia Grade 2/3, Carcinoma Cervix
Extended VALidation of HUman Papillomavirus Assays and Collection DEvices for HPV Testing on Self-samples
The "Extended VALHUDES" study is a Clinical Performance / Diagnostic Test Accuracy Study that aims to extend validation, achieved as part of the "Belgian VALHUDES", of HPV testing using BD Onclarity on samples collected using…
- Trial name
- Ext-VALHUDES (NCT04788849)
- Testing
- BD Onclarity™ HPV assay
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Fetal Monitoring
Remote Pregnancy Monitoring to Improve Access
The goal of this clinical trial is to determine the effectiveness of remote nonstress test (NST) compared to in-clinic NSTs in improving fetal testing completion rates.
- Trial name
- REACTIVE (NCT05847790)
- Testing
- Invu monitoring belt, Standard of care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Pennsylvania
Stress Urinary Incontinence
Is the Cough Stress Test Equivalent to the 24 Hour Pad Test in the Assessment of Stress Incontinence?
The purpose of this research study is to identify if the cough stress test is equal to the 24hour pad test in assessing stress urinary incontinence.
- Trial name
- NCT01123096
- Testing
- Cough Stress Test, 24 Hour Pad Test
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
HIV/AIDS and Infections, Sexually Transmitted Diseases
Puerto Rico Cuidalos Parent-adolescent Program
Latino adolescents are at high risk for HIV/AIDS, other sexually transmitted infections (STIs), and unintended pregnancies. Puerto Rican adolescents, in particular, experience disparities in these areas, yet few adolescent and…
- Conditions
- HIV/AIDS and Infections, Sexually Transmitted Diseases, Pregnancy Prevention
- Trial name
- NCT03063385
- Testing
- Parental Communication intervention, Health promotion control condition
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Bladder Carcinoma, Bladder Urothelial Carcinoma
Testing Anti-Cancer Drugs Erdafitinib With or Without Atezolizumab in Patients With Localized Bladder Cancer Not Able to Receive Cisplatin Chemotherapy, NERA Trial
This phase II trial compares the effect of erdafitinib alone to using the combination of erdafitinib and atezolizumab in treating patients with bladder cancer whose tumor invades the muscular bladder wall (muscle invasive)and who…
- Conditions
- Bladder Carcinoma, Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma, Renal Pelvis and Ureter Urothelial Carcinoma
- Trial name
- NCT05564416
- Testing
- Atezolizumab, Biospecimen Collection, Computed Tomography
- Sponsor
- National Cancer Institute (NCI)
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