Clinical trials: Pregnancy Tests
Acute Kidney Injury
ProNephro NGAL Test for Early Detection of Acute Kidney Injury in Adult ICU Patients (ALPACA)
The purpose of this study is to evaluate the performance of the ProNephro AKI™ (NGAL) test for identifying critically ill adults at risk of developing moderate to severe acute kidney injury (KDIGO Stage 2/3) within 48 to 72 hours…
- Trial name
- ALPACA (NCT07751913)
- Testing
- ProNephro AKI™ (NGAL)
- Where
- 4 sites in United States
- Volunteers
- 800 people
- Sponsor
- BioPorto Diagnostics
Gestational Diabetes Mellitus (GDM), Pregnancy Complications
Glycemic Markers for Predicting Gestational Diabetes in Pregnant Women With Previous Bariatric Surgery
Gestational diabetes mellitus (GDM) is associated with significant maternal and fetal complications. The standard diagnostic test for GDM is the 75-gram oral glucose tolerance test (OGTT).
- Conditions
- Gestational Diabetes Mellitus (GDM), Pregnancy Complications, History of Bariatric Surgery
- Trial name
- BARI-GDM (NCT07517406)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Burak Deniz Aydoğdu
Critical Illness, Oliguria
Performance of Diuretic Stress Test in Predicting Short Term Renal Recovery in Oliguric Critically-ill Patients Recovery in the Short Term
Acute kidney injury (AKI) is a common disorder and associated with high morbidity and mortality. However, distinguishing transient AKI from persistent AKI may help in individualizing treatment and limit short and long term…
- Trial name
- NCT02800135
- Testing
- Furosemide
- Where
- 4 sites in France
- Volunteers
- 93 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
End Stage Kidney Disease (ESKD), Hyperglycaemia
Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring
This study will evaluate whether Continuous Glucose Monitoring (CGM) can identify previously unrecognized diabetes and clinically significant hyperglycemia in adults with end-stage kidney disease (ESKD) receiving hemodialysis who…
- Conditions
- End Stage Kidney Disease (ESKD), Hyperglycaemia, Diabetes
- Trial name
- NCT07880795
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Emory University
Gestational Diabetes, Postpartum Disorder
Self-Administered 2-Hour Oral Glucose Tolerance Test
The goal of this randomized controlled trial is to evaluate whether self-administered postpartum diabetes screening tests in patients with gestational diabetes improves screening completion rates.
- Conditions
- Gestational Diabetes, Postpartum Disorder, Gestational Diabetes Mellitus in Pregnancy
- Trial name
- NCT06099509
- Testing
- Self-administered oral glucose tolerance test
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Prisma Health-Upstate
Non Muscle Invasive Bladder Cancer, Treatment by BCG
Effect on Xpert® Bladder Test of Urines Inflammatory Milieu Induced by BCG Treatment of Patients With NMIBC
Intravesical BCG immunotherapy is used after transurethral resection (TUR) for the prevention of recurrence of NMIBC. BCG treatment is usually started a few weeks after TUR and is given once a week for 6 weeks.
- Trial name
- CEPHEID (NCT02895620)
- Testing
- Xpert bladder Test
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Institut Claudius Regaud
Urinary Incontinence
Computerized-Adaptive Testing: Feasibility In Women With Pelvic Floor Disorders (CAT)
The objective of this pilot-study is to evaluate the feasibility and acceptability of PROMIS computerized-adaptive testing in women with urinary incontinence.
- Trial name
- CAT (NCT01288703)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Cardiac Ion Channelopathy
Post-mortem Genetic Testing
This is a prospective observational study to examine the incidence of cardiac ion channelopathies in unexplained still births.
- Trial name
- NCT01120886
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Thayyil, Sudhin
Diabetes Insipidus
A Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001 Given for Multiple Days and to Test How NDI-5001 is Tolerated and Taken up in the Body
The primary purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of NDI-5001 administered as a capsule following daily oral dosing in adult males with X-linked congenital…
- Trial name
- NCT07525960
- Testing
- NDI-5001
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Urothelial Carcinoma
Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer
Urothelial cancers of the bladder and upper urinary tract account for over 200,000 deaths and 600,000 diagnoses annually worldwide.
- Trial name
- UROSCOUT-1 (NCT06310759)
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 3,000 people
- Sponsor
- Tampere University Hospital
Medical Abortion
Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan
This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in…
- Trial name
- NCT02343913
- Testing
- PAC checklist
- Where
- 15 sites in Pakistan
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Uterine Cervical Neoplasm, Uterine Cervical Dysplasia
Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples
The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers.
- Conditions
- Uterine Cervical Neoplasm, Uterine Cervical Dysplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- COMBISCREEN (NCT06598176)
- Testing
- Colli-Pee 20mL device with UCM, Evalyn Brush
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universiteit Antwerpen
Postpartum Depression
bBeAMom: Effectiveness of a Cognitive-Behavioral Blended Intervention for Postpartum Depression
Be a mom program (a web-based cognitive-behavioral intervention) is being tested in another clinical trial as a preventive intervention for postpartum depression (NCT03024645).
- Trial name
- bBeAMom (NCT04441879)
- Testing
- Be a Mom Coping with Depression, Be a Mom
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- University of Coimbra
Cervical Cancer Cin Grade
New Methods of Distribution of a Self Sampler Kit for Cervical Cancer Screening
The opportunity of a home, self-collected sample, opens the chance to remove some of the barriers that may discourage women from participating to screening programmes or performing HPV (Human Papilloma Virus)-test.
- Trial name
- NMDSS2 (NCT01647724)
- Where
- Italy
- Volunteers
- 15,000 people
- Sponsor
- Azienda Sanitaria Locale 4, Teramo
Human Papillomavirus DNA Tests, Cervical Cancer
IT-system Development for Reaching Cervix Cancer Screening Non-attenders
The main purpose is to develop and test an IT-infrastructure to provide more individualized ways of inviting and reaching women who have not participated, despite having been invited with annual reminders, in cervix cancer…
- Trial name
- NCT02750124
- Testing
- Cobas PCR Female swab sample Packet, Routine practice
- Volunteers
- 8,000 people
- Sponsor
- Karolinska Institutet
Ovarian Carcinoma
PEP-DC and OC-DC Vaccine in High Grade Serous Ovarian Carcinoma
Single center, phase I/II randomized 2-arm study, evaluating two different vaccination regimens combined with low-dose cyclophosphamide in patients with advanced high grade serous ovarian carcinoma (HGSOC): Arm A patients will be…
- Trial name
- CHUV-OVACURE (NCT05714306)
- Testing
- PEP-DC1, OC-DC, PEP-DC2
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Stress
Assessment of Stress Levels in Consumers Using Ovulation Tests in Order to Conceive
Approximately 150 female volunteers wishing to become pregnant will be recruited via web recruitment from around the UK and randomised 1:1 to receive Clearblue Digital ovulation tests (active arm) or no aid to conception (control…
- Trial name
- NCT01084304
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Fetal Sex Determination
Evaluation of Fetal Sex in Assisted Reproductive Technology (ART) Achieved Pregnancies
Whole blood and urine samples will be collected from pregnant woman of gestational age 36-56 days as confirmed by artificial reproductive technology (ART).
- Trial name
- PREVIEW (NCT01021085)
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Sequenom, Inc.
Ovarian Cancer
Exploiting Pathogenic Tp53 Mutation for Early Diagnosis of Ovarian Cancer by Mean of Papanicolau Test
The aim of the project is to corroborate them on a large retrospective cohort of HGS-EOC and confirm the possibility of identify TP53 mutations in high grade endometrioid tumors.
- Trial name
- PAPAudit (NCT04812938)
- Testing
- Patients with Ovarian cancer and pap test available
- Where
- 2 sites in Italy
- Volunteers
- 190 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Renal Cell Carcinoma
Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer
The purpose of this trial is to examine the safety, feasibility, immunological response, and clinical antitumor activity of multiple administrations of dendritic cell Immunotherapeutic to patients with newly diagnosed with…
- Trial name
- NCT00272649
- Testing
- AGS-003
- Where
- 10 sites in United States, Canada
- Volunteers
- 22 people
- Sponsor
- Argos Therapeutics
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