Clinical trials: Pregnancy Tests, open to volunteers
Chronic Kidney Disease Stage 3 and 4, Diabetes
Prediction of Peripheral Neuropathy With Functional Testing
Diabetes and chronic kidney disease (CKD) are two distinct pathologies. The former is defined as an impairment in insulin production and/or utilization, while the latter refers to structural or functional abnormalities of the…
- Trial name
- PredictNP (NCT06933108)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Université catholique de l'Ouest
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma
- Trial name
- NCT05334069
- Testing
- Questionnaire Administration, Biospecimen Collection
- Where
- 751 sites in United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Cervical Cancer Recurrent, Radiotherapy
HPV After chemoRadioTherapy
The HART (HPV After chemoRadiotherapy) study is a prospective multicenter observational trial designed to evaluate the clinical utility of HPV testing in the follow-up of patients treated with definitive chemoradiotherapy (CRT)…
- Conditions
- Cervical Cancer Recurrent, Radiotherapy, Cell Free DNA, HPV
- Trial name
- HART (NCT07493928)
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- General University Hospital, Prague
Ovarian Cancer
Spanish Decision Tool for Ovarian Cancer Maintenance Therapy
To develop a shared decision-making (SDM) tool to help Spanish-speaking patients make decisions about their maintenance therapy
- Trial name
- NCT06036810
- Testing
- Shared Medical Decision Tool, Engaging Patients in Decision Making, Literacy Spanish Language
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- M.D. Anderson Cancer Center
Urinary Tract Infections, Antiobiotic Stewardship
Post-Emergency Optimization of Antibiotic Therapy for Urinary Tract Infection (UTI)
Prospective, multicenter, non-interventional study conducted over 6 months, including patients presenting to the emergency department with suspected urinary tract infection managed as outpatients and discharged with or without…
- Conditions
- Urinary Tract Infections, Antiobiotic Stewardship, Emerging Infectious Disease
- Trial name
- REVIU48 (NCT07559318)
- Testing
- Adaptation of antibiotics therapy for outpatient urinary infection following emergency care
- Where
- 3 sites in France
- Volunteers
- 330 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Treponema Pallidum, Treponema Pallidum Infection
This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.
This study will evaluate the clinical performance of two investigational diagnostic kits developed by ALPCO: the Syphilis-T CLIA Kit and the Syphilis-NT CLIA Kit.
- Conditions
- Treponema Pallidum, Treponema Pallidum Infection, Syphilis Infection, Serum
- Trial name
- NCT07089836
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Ovarian Cancer, Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies
This study will recruit patients with the following cancer indications: ovarian cancer, squamous non-small cell lung cancer, synovial sarcoma and head and neck cancer, with inoperable locally advanced or metastatic solid tumours.
- Conditions
- Ovarian Cancer, Squamous Non-Small Cell Lung Cancer (NSCLC), Synovial Sarcomas, Head and Neck Cancer
- Trial name
- NCT07613723
- Testing
- ZI-MA4-1 (TCR-NK cells), Cyclophosphamide, Fludarabine
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- Zelluna Immunotherapy AS
High Risk Pregnancy, Remote Patient Monitoring
Remote Fetal Monitoring in High Risk Pregnancies
Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered.
- Conditions
- High Risk Pregnancy, Remote Patient Monitoring, Diabetes, Hypertension
- Trial name
- NCT06822439
- Testing
- Fetal ECG monitoring
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Beth Israel Deaconess Medical Center
Uterine Cervical Neoplasm, Uterine Cervical Dysplasia
Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples
The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers.
- Conditions
- Uterine Cervical Neoplasm, Uterine Cervical Dysplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- COMBISCREEN (NCT06598176)
- Testing
- Colli-Pee 20mL device with UCM, Evalyn Brush
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universiteit Antwerpen
Endometrial Carcinoma
Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer
This study evaluates how women feel about using DNA from a vaginal fluid collection for early detection of endometrial cancer.
- Trial name
- NCT07527143
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cervical Cancer Screening, Cervical Cancer
Culturally Adapted Materials to Increase Cervical Cancer Screening Among Polish Women in Iceland
This study tests whether sending Polish women residing in Iceland a culturally adapted invitation letter - tailored in language and messaging to the target group - increases participation in cervical cancer screening compared…
- Conditions
- Cervical Cancer Screening, Cervical Cancer, Cervical Cancer (Early Detection)
- Trial name
- NCT07856862
- Testing
- Culturally adapted cervical cancer screening invitation letter, Standard cervical cancer screening invitation letter
- Where
- Iceland
- Volunteers
- 2,000 people
- Sponsor
- The Primary Health Care in the Capital Area
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Neoplasms (Cancer / Tumors), Colorectal Neoplasms
A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment
Many clinical trials evaluating cancer treatments require patients to undergo testing for specific molecular markers as part of eligibility screening, typically using immunohistochemistry or sequencing.
- Conditions
- Neoplasms (Cancer / Tumors), Colorectal Neoplasms, Lung Neoplasms, Endometrial Neoplasms
- Trial name
- FATHOM (NCT07814872)
- Where
- United States
- Volunteers
- 30,000 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Endometrial Cancer, Methylation
Clinical Studies of Endometrial Cytology and Cervical Methylation Assays in Endometrial Cancer Screening and Fertility-Preservation Evaluation
The current study aims to assess high-risk patients using both liquid-based cytology and cervical methylation testing. The results will be compared with the traditional hysteroscopic pathological findings to determine the…
- Conditions
- Endometrial Cancer, Methylation, Cytology, Fertility Preservation
- Trial name
- NCT06672341
- Testing
- Endometrial Cytology Testing, Cervical Methylation Testing
- Volunteers
- 200 people
- Sponsor
- Yulan Ren
Syphilis
Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department
The purpose of this study is to offer routine lab-based and rapid point of care (POC) syphilis diagnostic testing in the emergency department (ED) and obstetrical (OB) triage , thereby increasing screening and treatment…
- Trial name
- NCT06645106
- Testing
- Rapid Point of Care (POC) Syphilis testing
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- The University of Texas Health Science Center, Houston
HPV Infection, Cervical Cancers
Remote Resilience: Novel Applications of mHealth in Nicaragua's Cancer Control Program
The goal of this clinical trial is to test an mHealth intervention for cervical cancer prevention in under-screened women ages 25-64 on the Caribbean Coast of Nicaragua.
- Trial name
- NCT06921798
- Testing
- mHealth
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Ovarian Cancer
Study to Assess Prevalence of the Folate Receptor Alpha (FRa) in Adult Female Participants With Ovarian Cancer in Intercontinental (InterCon) Countries
Epithelial ovarian cancer (OC), including fallopian tube and primary peritoneal cancer, is the deadliest gynecologic malignant neoplasm with a 5-year relative survival of approximately 50%.
- Trial name
- ConFeR (NCT07539844)
- Where
- 12 sites in Argentina, Brazil and 3 more
- Volunteers
- 1,000 people
- Sponsor
- AbbVie
Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis)
Improving Perinatal Outcomes Among Kenyan Pregnant Women With an Integrated STI Testing Model
The investigators will conduct a 3-arm individual-level RCT in Kisumu and Siaya, Kenya to compare perinatal outcomes associated with 3 models of STI testing and management in antenatal care.
- Trial name
- PrIMI (NCT06203951)
- Testing
- Xpert® CT/NG and TV testing
- Where
- 8 sites in Kenya
- Volunteers
- 3,132 people, healthy volunteers welcome
- Sponsor
- University of Washington
Treponema Pallidum Infection, Chlamydia Trachomatis Infection
Improving Maternal and Child Health Through Point-of-care STI Testing
The goal of this clinical trial is to learn if point-of-care tests (POCTs) for sexually transmitted infections (STIs) improve the timely treatment of syphilis, chlamydia, gonorrhea, and trichomonas in pregnant women.
- Conditions
- Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis
- Trial name
- MATCH-POINT (NCT07290439)
- Testing
- Point-of-care STI tests, Standard of care STI testing
- Where
- United States
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Emory University
Hematuria
Study on Risk Assessment for Patients With Microscopic Hematuria (Non-Visible Blood in Urine) Using a Urine Marker Test
The goal of this clinical study is to learn how well a urine test called Xpert® Bladder Cancer Detect (Xpert BC-D) can help doctors assess the risk of bladder cancer in people with non-visible blood in their urine (microscopic…
- Trial name
- UroDetect III (NCT07307300)
- Where
- Germany
- Volunteers
- 1,475 people
- Sponsor
- Christian Bolenz