Clinical trials: Pregnancy Trimester, Second
Preeclampsia Severe, Preeclampsia Second Trimester
Metformin and Esomeprazole For Preterm Pre-eclampsia
A recent randomized controlled trial by Cluver et al included 180 women with preterm pre-eclampsia between 26+0 to 31+6 weeks' gestation undergoing expectant management: 90 were randomised to extended release metformin and 90 to…
- Conditions
- Preeclampsia Severe, Preeclampsia Second Trimester, Preterm Birth Complication
- Trial name
- NCT05232994
- Testing
- Esomeprazole 20mg
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Christiana Care Health Services
Abortion in First Trimester, Abortion, Second Trimester
Second-trimester TOP : a Retrospective Study Comparing Complications at 12-14 vs 14-16 Weeks of Gestation
In France, the recently adopted law relating to the legal time limit for access to voluntary interruption of pregnancy has set a threshold of the term at which it can be performed up to 16 weeks of gestation.
- Trial name
- NCT05469594
- Volunteers
- 122 people
- Sponsor
- Central Hospital, Nancy, France
CARBETOCIN FOR PREVENTION OF PLACENTAL RETAINED
Randomized Clinical Trial for Comparison Of Intravenous Carbeitocin Versus Oxytocin In Management Of Placental Delivery In Second Trimester Interruption
Intravenous Carbetocin is more efficient than intravenous infusion oxytocin in management of placental delivery in 2nd trimester interruption.
- Trial name
- NCT01827124
- Testing
- Carbetocin, oxytocin
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Wafaa Uthman Ahmed
Second Trimester Abortion
Second Trimester Pregnancy Termination in Women With Previous Caesarean Sections
it is a randomized controlled trial comparing the safety and efficacy of Vaginal Misoprostol versus combined Intracervical Foley's Catheter and Oxytocin Infusion for Second Trimester Pregnancy Termination.
- Trial name
- NCT04501809
- Testing
- compare misoprostol with combined oxytocin and cervical foly catheter
- Where
- 2 sites in Egypt
- Volunteers
- 158 people
- Sponsor
- Zagazig University
Pregnancy Termination
Second Trimester Pregnancy Termination With Foley Catheter
One of the methods used to induce second trimester pregnancy termination is the placement of a transcervical Foley catheter. The aim of this randomized controlled study was to assess in pregnant women with an unfavourable cervix…
- Trial name
- NCT03532503
- Testing
- Foley catheter
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy Trimester, First, Pregnancy Trimester, Second
Clinical Trial to Assess the Influence of Gestational Stage and Maternal Age on Arterial Stiffness of the Mother
This is a single-centre, open, parallel-group study with three age groups; no study medication or intervention will be provided. This is a longitudinal follow-up of physiological parameters.
- Conditions
- Pregnancy Trimester, First, Pregnancy Trimester, Second, Pregnancy Trimester, Third
- Trial name
- NCT00180219
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Legally Induced Abortion Without Mention of Complication
Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
This research study investigates the use of a drug, mifepristone, given before second trimester abortion. Mifepristone is a medication that is approved for medical abortion during the first trimester.
- Trial name
- POEM (NCT01862991)
- Testing
- Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Induced Abortion, Second Trimester Abortion
Midlevel Versus Physician-provided Medical Abortion in the Second Trimester
The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians.
- Conditions
- Induced Abortion, Second Trimester Abortion, Medical Abortion, Health Personnel
- Trial name
- NCT04181541
- Testing
- Provider type: Physicians, Provider type: Midlevel Providers
- Where
- Ethiopia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ipas
Preeclampsia, IUGR
Prediction of Preeclampsia & Other Obstetric Complications by Serum Homocysteine & Doppler
Second trimester homocysteine \& uterine artery doppler will be assessed\& the cases will be followed up till delivery for development of preeclampsia, IUGR(intra-uterine growth retardation) \& other obstetric complications.
- Trial name
- NCT02541110
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Termination of Pregnancy Second Trimester
Misoprostol for Second Trimester Termination of Pregnancy
To compare the efficacy of two different dose regimens of misoprostol administered vaginally in combination with mifepristone in second trimester termination of (non)viable pregnancy.
- Trial name
- MIMIS (NCT00945997)
- Testing
- misoprostol
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Zika Virus Infection
Sensorimotor Outcomes of Children Exposed to Foetal Zika Virus Infection
Introduction: It is estimated that more than one million Brazilians were infected by zika virus in the last two years. Brazilian researchers first noted the virus's potential association with microcephaly.
- Trial name
- NCT03679728
- Testing
- First trimester, Second trimester
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Second Trimester Abortion
TENS Unit To Decrease Pain After Laminaria Insertion
The purpose of the study is to learn more about the transcutaneous nerve stimulation (TENS) unit, an over-the-counter option for pain relief that is not a medication.
- Trial name
- NCT06529003
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) unit
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Queen's Medical Center
Premature Labour
Vaginal Progesterone Versus Cervical Cerclage for Pregnant Women With Short Cervix and History of PTL and/or MTM
The aim of this study to compare vaginal progesterone supplementation to cervical cerclage for prevention of preterm labor in women with short cervical length and history of previous midtrimester miscarriage and/or preterm labor.
- Trial name
- NCT02673359
- Testing
- Progesterone, Cervical cerclage
- Where
- 3 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Mohamed Sayed Abdelhafez
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00957346
- Testing
- Mifepristone+misoprostol
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pregnancy Termination in Second Trimester
Nitrous Oxide Versus Intravenous Sedation for Anesthesia
This study is a multi-site, double-blinded, randomized, non-inferiority clinical trial of inhaled nitrous oxide with oxygen (N2O/O2) versus intravenous (IV) sedation, with fentanyl and midazolam, for pain management in adult…
- Trial name
- NOVIA (NCT02755090)
- Testing
- Nitrous Oxide, IV Saline
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Artifical Intelligence, Echography Ultrasound
Study Comparing Two Image Acquisition Modalities for Second-trimester Pregnancy Screening Ultrasound
The second-trimester morphology ultrasound is a key examination in obstetric monitoring that aims to assess fetal growth, identify any structural abnormalities, and inspect anexes such as placenta, umbilical cord, cervix,...
- Trial name
- Echo-IA (NCT07286591)
- Testing
- Standard Ultrasound, US with AI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Clinique Rive Gauche
HIV, Hepatitis B
Safety Study of a Tenofovir-containing Drug Regimen for the Prevention of Mother-to-child Transmission of HIV and HBV
The purpose of this study is to compare a regimen of tenofovir/lamivudine/lopinavir-ritonavir to the WHO-recommended and locally practiced standard of care regimen consisting of zidovudine/lamivudine/lopinavir-ritonavir during…
- Trial name
- TiP (NCT01125696)
- Testing
- Tenofovir/lamivudine/lopinavir-ritonavir, Zidovudine/lamivudine/lopinavir-ritonavir
- Where
- 2 sites in China
- Volunteers
- 45 people
- Sponsor
- Centers for Disease Control and Prevention
Abortion, Second Trimester
24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
This study aims to compare mifepristone and buccal misoprostol to mifepristone and vaginal misoprostol for cervical preparation for second trimester dilation and evacuation (D\&E).
- Trial name
- NCT03134183
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Miscarriage
Estradiol Pretreatment With Misoprostol in Second Trimester Miscarriage
To compare the effectiveness of estradiol pretreatment with misoprostol and vaginal misoprostol alone in induction of second trimestr miscarriage.
- Trial name
- NCT03479879
- Testing
- Estradiol, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Gestational Diabetes, Obesity
Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
This is a prospective, randomized, placebo controlled study with three parallel arms examining the effects of magnesium supplementation in the second trimester of pregnancy.
- Trial name
- NCT01510665
- Testing
- Magnesium citrate, Dietary modification
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles