Clinical trials: Pregnancy Trimester, Second
Induction of Second Trimester Abortion
Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion
The aim of this work is to assess the effectiveness and safety of Ulipristal Acetate in the management of 2nd trimester missed abortion along with misoprostol in pregnant women with previous caesarean section versus the use of…
- Trial name
- NCT04989400
- Testing
- Ulipristal Acetate, Misoprostol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion, Second Trimester
Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
The purpose of this study is to determine whether a Foley balloon is similar to osmotic dilators for preparing the cervix prior to a second trimester abortion.
- Trial name
- NCT05099991
- Testing
- Single Foley Balloon, Dilapan-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pregnancy
Intravaneous Iron(1000 mg Low Molecular Weight Iron Dextran Over 60 Minutes) for Pregnant Women
To determine the percentage of women who achieve anemia correction after a single dose of 1000mg of low molecular weight iron dextran(infed).
- Trial name
- NCT02038023
- Testing
- Intravaneous iron(low molecular weight iron dextran)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Auerbach Hematology Oncology Associates P C
Sleep Initiation and Maintenance Disorders, Sleep
Sleep Disturbances in the 2nd and 3rd Trimester
Sleep disorders and disturbances are mostly underestimated in clinical practice. Moreover, this problem is generally neglected by the pregnant themselves.
- Conditions
- Sleep Initiation and Maintenance Disorders, Sleep, Sleep Apnea, Sleep Disorder
- Trial name
- NCT03763071
- Testing
- Patient-reported scales to measure sleep disorders
- Where
- Turkey (Türkiye)
- Volunteers
- 683 people, healthy volunteers welcome
- Sponsor
- Bartin State Hospital
Groin Strain
Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy
The study will focus on the effects of active tissue release techniques on groin pain, hip range of motion, and functional disability in 2nd trimester of pregnancy.
- Trial name
- NCT06340126
- Testing
- Active release techniques, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pregnancy, Gestational Diabetes Mellitus
Predictability of Gestational Diabetes Mellitus in First and Second Trimester
The objective of the study is, if an early oral glucose tolerance test combined with maternal history, condition and multiple biomarker analysis can be used to detect gestational diabetes mellitus in the first trimester (12-14…
- Trial name
- GDMPredict (NCT02035059)
- Where
- Switzerland
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postnatal Complication, Mesenteric Pregnancy
Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus.
Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus.
- Trial name
- MALROT (NCT05148429)
- Testing
- Ultrasound exam, Fetal MRI, Postnatal abdominal ultrasound
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Lactation Suppressed
Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Loss
This research study investigates the use of a drug, cabergoline, given immediately after second-trimester abortion or perinatal loss to decrease breast engorgement.
- Trial name
- LISTA (NCT04701333)
- Testing
- Cabergoline 1 MG
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Stanford University
Other Abortion
Misoprostol vs. Sublingual Misoprostol and Laminaria For Second Trimester Termination of Pregnancy
1. Comparison between the duration of time from the beginning of cervical preparation until abortion, between sublingual misoprostol and the combination of sublingual misoprostol with laminaria for second trimester medical…
- Trial name
- NCT02013960
- Testing
- Cytotec
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Hemorrhage
Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation
The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.
- Trial name
- NCT06141447
- Testing
- Oxytocin + normal saline, Normal saline
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Termination of Pregnancy
Ulipristal Acetate for Cervical Preparation
This is a prospective cohort study exploring a broadened use of ulipristal acetate as a cervical preparation agent for second trimester surgical abortion.
- Trial name
- U-Prep (NCT03802149)
- Testing
- Ulipristal Acetate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Placenta Previa Complete Centralis
Accuracy of Rail Sign at Detection of PAS
Accuracy OF Rail Sign at Detection Of Placenta Accreta At The second And the Third Trimester Of Pregnancy By Ultrasound Scanning
- Trial name
- NCT07159997
- Testing
- Accuracy of rail sign by ultrasound st diagnosis placent previa
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Healthy Volunteers, Pregnancy Trimester, Second
The Effect of Antenatal Education on Fear of Birth, Physiological Ability to Give Birth and Traumatic Birth Perception
Today, pregnancy and childbirth are important life events that involve many challenges and changes for both men and women. During this process, changes occur in the pregnant woman's body, emotional state and family life.
- Conditions
- Healthy Volunteers, Pregnancy Trimester, Second, Pregnancy Trimester, Third, Nulliparity
- Trial name
- NCT06196151
- Testing
- Antenatal training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Abortion in Second Trimester
OPIOID Study - Pain With Osmotic Dilators
Comparison of pain levels and pain medications utilized following insertion of two different types of osmotic dilators.
- Trial name
- OPIOID (NCT03710239)
- Testing
- Dilapan-S, Laminaria
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Abortion in Second Trimester
Mifepristone and Misoprostol for Mid-trimester Termination of Pregnancy in Armenia
The primary goal of this study is to examine the efficacy and feasibility of a mifepristone combined with misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Armenia.
- Trial name
- NCT01766388
- Where
- 2 sites in Armenia
- Volunteers
- 120 people
- Sponsor
- Gynuity Health Projects
Pregnant, Exercise
The Impact of Dynamic Neuromuscular Stabilization on Pregnancy
The aim of this randomized controlled study is to determine the pregnancy and childbirth outcomes of using the DNS method to facilitate anatomical and physiological adaptations during pregnancy.
- Trial name
- NCT06239753
- Testing
- Dynamic Neuromuscular Stabilization, Standard Prenatal Education Program Implementation
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Dondu Kurnaz
Ultrasound, Transperineal
Evaluation of Transperineal Ultrasound Technic for Diagnostic Shorted Cervical Length for Pregnant Women (2nd and 3rd Trimester) Compared to Endovaginal Technic (Gold Standard)
Endovaginal ultrasound is currently the gold standard to diagnose a shorted cervical length and, by extension, assess the risk of preterm labor.
- Trial name
- ECHO (NCT04341597)
- Testing
- cervical ultrasound
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Medical; Abortion, Fetus
Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina Faso
The goal of this study is to examine the effectiveness and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Burkina Faso.
- Trial name
- NCT03269279
- Testing
- Mifepristone, Misoprostol
- Where
- 4 sites in Burkina Faso
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Oligohydramnios, Heparin
Effect of LMWH on Neonatal Outcomes in Isolated Oligohydramnios
The pregnant women who meet the study requirements will be included in the study. They will be randomly assigned to receive either the usual treatment or the usual treatment along with an additional medicine.
- Conditions
- Oligohydramnios, Heparin, Neonatal Outcomes
- Trial name
- NCT07907731
- Testing
- Enoxaparin (LMWH), Dextrose Water
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- PAEC General Hospital, Islamabad
Lumbopelvic Range of Motion in Second-Trimester Pregnancy
Exercise and Lumbopelvic Mobility in Pregnancy
Introduction. Pregnancy-induced biomechanical alterations frequently precipitate lumbopelvic mobility restrictions, contributing to musculoskeletal dysfunction and compromised maternal quality of life.
- Trial name
- NCT07447466
- Testing
- Effectiveness of a Six-Week Progressive Resistance Exercise Program on Lumbopelvic Range of Motion in Second-Trimester Pregnancy, Standard prenatal care
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Habil Hamdouni