Clinical trials: Pregnancy Trimester, Second
Stress Urinary Incontinence, Kegel's Exercise
Tactile Feedback Pelvic Floor Training to Prevent Stress Urinary Incontinence in the 3rd Trimester of Pregnancy
Pregnancy involves significant physiological changes, such as hormone fluctuations, weight gain, and fetal growth, which can affect multiple organ systems.
- Conditions
- Stress Urinary Incontinence, Kegel's Exercise, Sense of Touch, Physical Symptoms
- Trial name
- NCT07668128
- Testing
- Pelvic floor muscle training, Basic Health Education Group, Tactile pelvic floor muscle training group
- Where
- Taiwan
- Volunteers
- 141 people
- Sponsor
- Far Eastern Memorial Hospital
Uterine Artery Flow
Uterine Artery Doppler Changes
In uncomplicated pregnancies, the uterine spiral arteries undergo a series of structural changes that result in a low resistance in the uterine arteries as pregnancy progresses.
- Trial name
- NCT03064698
- Testing
- Post-partum Doppler ultrasound
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
PREGNANCY
Induction Versus Expectant Management With Abnormal Maternal Biochemical Markers
Induction of labor at term versus expectant management among women with abnormal maternal biochemical markers. A randomized controlled trial
- Trial name
- NCT02754635
- Testing
- Induction of labour, Expectant management
- Where
- Israel
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Anemia of Pregnancy, Iron Deficiency Anemia
Liposomal Iron 30 mg Supplement in Non-anemic Pregnant Females
Protocol Summary: Liposomal Iron Supplementation in Non-anemic Pregnant Females This observational study aims to evaluate the efficacy and safety of daily liposomal iron supplementation (30 mg) in non-anemic pregnant women during…
- Trial name
- LITSNPF (NCT06669052)
- Testing
- 30 mg liposomal iron, capsules
- Volunteers
- 714 people, healthy volunteers welcome
- Sponsor
- Orchidia pharmaceutical Industries
Abortion, Second Trimester
Induction of Abortion in the Second Trimester
To compare between the effects of misoprostol with hyoscine N-butyl bromide and misoprostol alone on shortening the time of abortion induction in the second trimester.
- Trial name
- NCT06207539
- Testing
- hyoscine N-butyl bromide under the generic name of buscopan ampoule produced by Sanofi company, misoprostol under the generic name of misotac tablets
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Preeclampsia, Severe Preeclampsia
Complement Regulation to Undo Systemic Harm in Preeclampsia
This is a Phase II, single arm, open-label study to determine if treatment with eculizumab prolongs pregnancy compared to historical controls in women with preeclampsia between 23-30 weeks gestation.
- Conditions
- Preeclampsia, Severe Preeclampsia, Eculizumab, HELLP
- Trial name
- CRUSH (NCT04725812)
- Testing
- Eculizumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cedars-Sinai Medical Center
Abortion in Second Trimester
Outpatient Service for Mid-trimester Termination of Pregnancy
This study seeks to evaluate the safety, acceptability and feasibility of an outpatient "day procedure" for medical abortion at 13-18 weeks gestation.
- Trial name
- NCT03346629
- Testing
- Mifepristone + Misoprostol
- Where
- 3 sites in Nepal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Lactation Suppressed
Cabergoline for Lactation Inhibition After Early Second-Trimester Abortion or Pregnancy Loss
Breast pain following second-trimester abortion is common. Breast engorgement and milk leakage following second-trimester perinatal loss and abortion can cause both physical pain and emotional distress.
- Trial name
- eLISTA (NCT06029673)
- Testing
- Cabergoline 1 MG
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Stanford University
Pre-Eclampsia
Predictors of Intrauterine Growth Restriction
The main objectives of modern antenatal care programs are to identify high risk pregnancies then to predict any possibility of adverse pregnancy outcome as early as possible.
- Trial name
- NCT03349671
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
HIV, Pregnancy
The Effect of Pregnancy on the PK of Isentress®: A Longitudinal Investigation in the Second and Third Trimesters
The purpose of this study is to determine whether pregnancy affects the blood concentrations of raltegravir by comparing the second trimester and third trimester drug concentrations with post partum.
- Trial name
- NCT01251601
- Testing
- Pharmacokinetics
- Sponsor
- University of North Carolina, Chapel Hill
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Fetal Cisterna Magna Length, Ultrasonography
Influence of Imaging Angle in Measurement of Cisterna Magna
The aim of this study is to determine the effect of imaging angle on the measurement of fetal cisterna magna (CM) in the second trimester. Fetal CM will be prospectively measured in women at 18-24.6 weeks' gestation.
- Trial name
- NCT03697902
- Testing
- Ultrasonographic Measurement on Fetal cisterna magna length
- Where
- Mexico
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Abortion, Induced
Pilot Study of the Addition of Osmotic Dilators to Preparation Prior to Labor Induction Abortion
One the day prior to medical abortion (labor induction) in the second trimester, insertion of osmotic dilators is added to the routine procedures.
- Trial name
- DAIS (NCT00855842)
- Testing
- osmotic dilator insertion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston University
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Induced Abortion
Comparison of Two Regimens of Misoprostol for Second Trimester Medical Termination of Pregnancy
The hypothesis of the study is that the induction abortion interval time will be significantly shorter in the group receiving vaginal misoprostol every six hours in comparison to the group who are receiving vaginal misoprostol…
- Trial name
- NCT00401440
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 185 people
- Sponsor
- Nilratan Sircar Medical College
Second Trimester Abortion
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater…
- Trial name
- NCT03407521
- Testing
- Misoprostol, isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy
Is Early Second Trimester Vaginal Ultrasound Scan Associated With Adverse Perinatal Outcomes?
Many pregnant women have an ultrasound done of their fetus in the beginning of the second trimester of pregnancy. Some have a transvaginal sonography while others have a transabdominal one, depending on clinical parameters such…
- Trial name
- NCT00909376
- Where
- Israel
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Abortion, Induced, Abortion, Second Trimester
A Pilot Study of Priming Before Induction Termination of Pregnancy
Induction termination of pregnancy (second trimester abortion) has a median time of 14 hours from the start of medication (misoprostol) to expulsion of the fetus.
- Trial name
- NCT00495560
- Testing
- Addition of misoprostol 25 mcg 12 hours before induction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boston University
Pregnancy Loss
Cervical Length on Pregnancy Termination
Cervical length is used as a parameter to predict cervical insufficiency and onset of labor. However, its role in predicting abortion induction is unclear.To investigate the impact of cervical length measurement and fetal…
- Trial name
- NCT04013035
- Testing
- cervical length measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital