Clinical trials: Pregnancy in Diabetic
Diabetic Nephropathy
Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and Microalbuminuria
1. The primary objective of this study was： in patients with type 2 diabetes and microalbuminuria who have been receiving stable treatment of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker (ACEI/ARB) for…
- Trial name
- NCT02035891
- Testing
- colchicine 0.5mg/d
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chongqing Medical University
Diabetes in Pregnancy, Type 2 Diabetes
Hydroxychloroquine in Type 2 Diabetes During Pregnancy
The goal of this clinical trial is to compare the use of hydroxychloroquine as an adjunct to the current treatment of pregnant women with Type 2 diabetes mellitus.
- Trial name
- NCT06319560
- Testing
- Hydroxychloroquine Oral Tablet
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- National University of Malaysia
Non-diabetic Chronic Kidney Disease, Atherosclerosis
Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease
The aim of the study is to evaluate whether a low level of serum omentin-1 is associated with carotid atherosclerosis and mediated by inflammation.
- Trial name
- NCT01701830
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Hyperlipidemia
Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease
The purpose of this study is to evaluate the effects of Crestor (rosuvastatin) and (Lipitor) atorvastatin on urinary protein excretion over 1 year in non-diabetes with moderate proteinuria and hypercholesterolaemia.
- Trial name
- PLANET II (NCT00296400)
- Testing
- Rosuvastatin, Atorvastatin
- Where
- 107 sites in United States, Brazil and 9 more
- Volunteers
- 237 people
- Sponsor
- AstraZeneca
Diabetic Kidney Disease
Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease
To preliminarily evaluate the efficacy and safety of the renin inhibitor (SPH3127 tablets) in reduction in proteinuria in patients with diabetic kidney disease with valsartan as the comparator, and determine the recommended dose.
- Trial name
- NCT05593575
- Where
- 45 sites in China
- Volunteers
- 305 people
- Sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
Gestational Diabetes Mellitus in Pregnancy
Impact of DHA/Oat on Metabolic Health in Gestational Diabetes Mellitus
The randomized controlled trial (RCT) recruits pregnant women with de novo diagnosis of gestational diabetes. Women bearing a singleton pregnancy are randomized into four arms: DHA, oat, oat plus DHA, and placebo.
- Trial name
- NCT03569501
- Testing
- DHA, oat grains
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Essential Hypertension, Type 2 Diabetes
Sacubitril/Valsartan Treats Patients With Essential Hypertension and Type 2 Diabetic Nephropathy
This study aims to compare the efficacy and safety of Sacubitril/Valsartan versus Valsartan in patients with essential hypertension and type 2 diabetic nephropathy over a 12-week treatment period, including two treatment groups…
- Conditions
- Essential Hypertension, Type 2 Diabetes, Nephropathy
- Trial name
- Hyper-Save (NCT06501651)
- Testing
- Sacubitril/Valsartan, Valsartan
- Where
- China
- Volunteers
- 297 people
- Sponsor
- Sichuan Academy of Medical Sciences
Diabetic Nephropathies
Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL)
This study is a single center open-label randomized controlled trial designed to evaluate the efficacy of calcitriol plus losartan therapy in subjects with type II diabetes and macroalbuminuria.
- Trial name
- IDEAL (NCT02410005)
- Testing
- Calcitriol, Losartan
- Where
- 3 sites in United States, Qatar
- Volunteers
- 56 people
- Sponsor
- Weill Cornell Medical College in Qatar
Diabetes Mellitus, Diabetes, Gestational
Recent GDM Lifestyle Intervention
Women with a history of gestational diabetes (GDM) have a substantially increased risk of developing type 2 diabetes. In fact, 50-70% of these women will go on to develop type 2 diabetes within the 20 years following their…
- Trial name
- LIFe (NCT01910805)
- Testing
- Lifestyle and Risk Assessment class
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome, Diabete Type 2
Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
Several crosssectional and prospective studies have shown that metabolic syndrome and its related components are associated with both prevalent and incident CKD .
- Conditions
- Metabolic Syndrome, Diabete Type 2, Kidney Insufficiency
- Trial name
- NCT04485845
- Testing
- Vildagliptin, Captopril Tablets, MetFORMIN 500 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Cairo University
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy
The purpose of this study is to evaluate the effect of FG-3019 on diabetic kidney disease or diabetic nephropathy.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Diabetic Kidney Disease
- Trial name
- NCT00913393
- Testing
- FG-3019
- Where
- 28 sites in United States
- Volunteers
- 46 people
- Sponsor
- Kyntra Bio
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Pregnancy, Diabetes
Gastric Ultrasound in Term Pregnants
In this study, the investigators aimed to evaluate the gastric antrum with ultrasound and compare gastric volumes in diabetic and non-diabetic pregnant women in the standard fasting state before surgery.
- Trial name
- NCT06493110
- Testing
- Gastric ultrasound
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Gestational Diabetes Mellitus, Pregnancy
Trial of Remote Evaluation and Treatment of Gestational Diabetes Mellitus
Diabetes in pregnancy (gestational diabetes) is becoming more common. It can lead to problems for both mothers-to-be and their babies such as causing a large baby and difficult birth.
- Trial name
- TREAT-GDM (NCT01916694)
- Testing
- Blue tooth enabled glucose meter with smart phone application, Self home blood glucose monitoring
- Where
- United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Oxford
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hyperglycemia in Pregnant Diabetic Patients, Gestatiaonl Diabetes Mellitus
Shanghai Clinical Cohort of Hyperglycemia in Pregnancy
Establish a high-quality clinical cohort of hyperglycemia in pregnancy. Develop subtype-specific, end-to-end standards for diagnosis, treatment, and follow-up across the preconception, pregnancy, and postpartum phases.
- Trial name
- SHINE (NCT07161947)
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Shanghai General Hospital, China
Diabetic Nephropathies
Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy
This study was designed to assess the efficacy of adding pentoxifylline to losartan in comparison with increasing dose of losartan in type 2 diabetes patients with nephropathy.
- Trial name
- NCT03006952
- Testing
- Pentoxifylline, Losartan
- Where
- Iran
- Volunteers
- 59 people
- Sponsor
- Tehran University of Medical Sciences
Type 1 Diabetes Mellitus With Diabetic Nephropathy
Effect of Dietary Protein Restriction on Prognosis in Patients With Diabetic Nephropathy
The purpose of the investigators study was to determine the effect of dietary protein restriction on survival and progression to end stage renal disease (ESRD) in diabetic nephropathy.
- Trial name
- LPD (NCT01521910)
- Testing
- low protein diet, normal protein diet
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Steno Diabetes Center Copenhagen
Polycystic Ovary Syndrome
CANA/Met in Non-diabetic Women With PCOS
Polycystic ovary syndrome (PCOS), which is associated with hyperinsulinaemia, hyperandrogenaemia, impaired glucose metabolism and aberrant adipokines production from the adipose tissue, is a heterogeneous reproductive and…
- Trial name
- NCT04973891
- Testing
- Canagliflozin combined with metformin, metformin
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Shengjing Hospital
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC