Clinical trials: Pregnancy in Diabetic
Gestational Diabetes, Pregnancy in Diabetics
Texting for Diabetes Success in Pregnancy
Diabetes during pregnancy can be a challenging circumstance requiring extensive patient learning and self-care. The purpose of this study is to develop and pilot test a patient-centered diabetes education and self-care tool using…
- Trial name
- NCT03240289
- Testing
- Texting group
- Volunteers
- 33 people
- Sponsor
- Northwestern University
Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease Due to Type 2 Diabetes Mellitus
Effect of Treatment With Finerenone on Cardio-Renal Target Organ Damage in Patients With Type 2 Diabetes.
The global prevalence of diabetes is increasing substantially. Around 40 % of patients with type 2 diabetes develop chronic kidney disease.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease Due to Type 2 Diabetes Mellitus, Cardiovascular Diseases
- Trial name
- FineCaRe (NCT07026539)
- Testing
- Finerenone (BAY 94-8862)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Diabetic Kidney Disease, Diabetic Nephropathy
A Study in Participants With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in participants with kidney disease due to diabetes.
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathy, Diabetic Glomerulosclerosis
- Trial name
- NCT01113801
- Testing
- LY2382770
- Where
- 78 sites in United States, Australia and 5 more
- Volunteers
- 417 people
- Sponsor
- Eli Lilly and Company
Gestational Diabetes Mellitus in Pregnancy
A Novel Care Pathway in Women With "Low-risk" Gestational Diabetes Mellitus
This study is a randomized controlled trial to study the effect of the use of a risk stratification screening tool for high- and low-risk gestational diabetes mellitus (GDM), and the implementation of a new low-impact care…
- Trial name
- NCT05596812
- Testing
- New Care Pathway
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute
Diabetic Nephropathy
Effect of Sarpogrelate On the Nephropathy in Type 2 Diabetes (SONATA Study)
Phase 4 Study to evaluate the safety and effect on decreasing subjects' albuminuria who have Type 2 Diabetes by using sarpogrelate and placebo.
- Trial name
- NCT01869881
- Testing
- Anplag(Sarpogrelate)
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Yuhan Corporation
Chronic Kidney Diseases, Diabetic Kidney Disease
Real World Evidence Clinical Utility Study of KidneyIntelX
The purpose of this study is to assess the impact of the KidneyIntelX assay utilized as part of the current standard of care on the management of patients seen in the primary care physician's office at Mount Sinai.
- Trial name
- NCT04802395
- Testing
- KidneyIntelX
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Renalytix AI, Inc.
Diabetic Nephropathies, Peripheral Nervous System Diseases
A Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects With Diabetic Peripheral Neuropathy
This is a Phase 2, randomized, double-blind, placebo-controlled, dose range finding study in subjects who have diabetic peripheral neuropathy (DPN). The study will enroll approximately 24 subjects.
- Trial name
- NCT02552277
- Testing
- PDA-002
- Where
- 7 sites in United States
- Volunteers
- 26 people
- Sponsor
- Celularity Incorporated
Diabetes Mellitus, Kidney Disease
Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)
This study aims to investigate whether new glucose-lowering medications, such as SGLT2 inhibitors (e.g., Forxiga/Jardiance) and GLP-1 receptor agonists (e.g., Ozempic), can reduce NETosis in diabetic patients, thereby mitigating…
- Trial name
- NETs (NCT06821919)
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Diabetic Nephropathy
Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy
The purpose of this study is to determine whether oral sevelamer carbonate binds advanced glycation end products (AGEs) in the gastrointestinal (GI) tract of patients with diabetic nephropathy leading to decrease body AGE load…
- Trial name
- NCT00967629
- Testing
- Sevelamer Carbonate, Calcium Carbonate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
EMPRA (EMPagliflozin and RAs in Kidney Disease)
This study will be a prospective, clinical pilot study in CKD patients to show whether Empagliflozin in addition to ACEi treatment significantly increases Ang 1-7 levels compared to ACEi treatment alone.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
- Trial name
- EMPRA (NCT03078101)
- Testing
- Empagliflozin 10 MG [Jardiance]
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Vienna
Glomerulonephritis, Proteinuria
Empagliflozin in Patients With Glomerulonephritis
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are newly developed antihyperglycemic medications. In addition to their glucose lowering properties, they have been shown to have favourable effects on the cardiovascular and…
- Trial name
- NCT05283057
- Testing
- Empagliflozin 25 MG
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Diabetic Kidney Disease
Impact of Vitamin D on Diabetic Kidney Disease in African Americans
This purpose of this project is to evaluate the effectiveness of vitamin D supplementation over 12 months in vitamin D deficient African American adults with type 2 diabetes.
- Trial name
- NCT01214356
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Medical University of South Carolina
Diabetic Nephropathy
Efficacy of Telmisartan and the Combination of Telmisartan and Ramipril in type1 Diabetes Patients With Nephropathy
Hypothesis: The angiotensin receptor blocker telmisartan is effective at reduction of albumin excretion rate(AER) in patients with type1 diabetes and micro or macroalbuminuria.
- Trial name
- START1DM (NCT00738660)
- Testing
- Telmisartan, Ramipril
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Peripheral Neuropathy, Chemotherapy-induced, Disease Management
A Controlled Clinical Trial Assessing the Efficacy of Vitamin B Prophylaxis in Attenuating Paclitaxel-induced Neuropathy and the Imperative Use of Gabapentin in Diabetic Ovarian Cancer Patients and the Potential Effect on Disease Response.
The goal of this clinical trial is to learn if vitamin B prophylaxis is effective in attenuating chemotherapy-induced peripheral neuropathy in adult ovarian cancer patients.
- Trial name
- NCT07191587
- Testing
- Vitamin B Complex
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- National Cancer Institute, Egypt
Diabetic Nephropathy
Delaying the Progression of Diabetic Nephropathy in Pima Indians
A clinical intervention will be performed in adult diabetic Pima Indians with proteinuria to determine if an angiotensin converting enzyme (ACE) inhibitor is effective in slowing the progression of renal disease in persons with…
- Trial name
- NCT00353600
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pulmonary Aspiration, Gastric Content Aspiration
Ultrasound Assessment of Gastric Volume in Diabetic Versus Non-Diabetic Term Pregnant Women Undergoing Cesarean Section
The aim of the work to compare estimated gastric volumes through ultrasound in fasting diabetic and non-diabetic pregnant women scheduled for caesarean section.
- Trial name
- NCT06621706
- Testing
- Gastric ultrasonography
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
Diabetic Nephropathies
Possible Role of Roflumilast in Diabetic Nephropathy
adding roflumilast to the standard therapy for diabetic nephropathy and studying the progression of many outcomes including urinary albumin to creatinine ratio, estimated GFR, biomarkers of diabetic nephropathy
- Trial name
- NCT04755946
- Testing
- Roflumilast
- Volunteers
- 48 people
- Sponsor
- Tanta University
Diabetic Nephropathy
Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic Nephropathy
To determine the effects of three different doses of bardoxolone methyl administered orally on the kidney function (glomular filtration rate) in patients with diabetic nephropathy.
- Trial name
- NCT00664027
- Testing
- RTA 402 (Bardoxolone Methyl)
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Biogen
Diabetes in Pregnancy
Effects of Moderate Carbohydrate Consumption on Metabolic and Obstetric Outcomes in Pregnant Women With Insulin-treated Diabetes- A Randomized Controlled Trial
Diabetes during pregnancy increases maternal and fetal complications, necessitating optimal glycemic control. The standard care diet (SCD, ≥175g/day carbohydrate) lacks robust evidence, particularly for pregnancies requiring…
- Trial name
- NCT06355154
- Testing
- Nutritional intervention
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hadassah Medical Organization