Clinical trials: Pregnancy in Diabetic
Diabetic Kidney Disease
To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy
This is a large-scale, multi-center, observational study. It is planned to establish a large database of 10,000 patients with type 2 diabetes mellitus to investigate the prevalence, awareness and screening rates of diabetes…
- Trial name
- NCT05047471
- Where
- 50 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Yiming Mu
Gestational Diabetes Mellitus, Pregnancy in Diabetic
Patient Versus Provider-led Titration of Insulin for Glycemic Control in Gestational Diabetes (EMPOWER)
We propose a pragmatic, unblinded, randomized controlled, single center trial of 56 pregnant individuals with Gestational diabetes mellitus (GDM).
- Conditions
- Gestational Diabetes Mellitus, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT05922033
- Testing
- Patient-led Insulin (intervention group), Provider-led Insulin (standard care)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University
Diabetes in Pregnancy
Meal Composition and the Influence on Pre-prandial Blood Glucose Values
The purpose of the proposed study is to assess the distribution of carbohydrates and fat in the diet of women with type 1 diabetes during pregnancy.
- Trial name
- NCT03028506
- Testing
- Carbohydrate intake
- Volunteers
- 50 people
- Sponsor
- St. Louis University
Diabetic Kidney Disease (DKD)
Rubix LS Diabetic Kidney Disease (DKD) Registry Study
Diabetic kidney disease (DKD) is a common complication of type 2 diabetes that can lead to kidney failure and increases the risk of cardiovascular disease.
- Trial name
- NCT07348718
- Testing
- Kidney-Protective Therapies Used in Routine Care
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Rubix LS
Infant, Newborn, Diseases, Pregnancy in Diabetics
Diazoxide In the Management Of Hypoglycemic Neonates
Diazoxide is an oral hyperglycemic medication. Diazoxide has been proven effective for treating hypoglycemia in infants and children with some types of persistent hyperinsulinemic hypoglycemia.
- Conditions
- Infant, Newborn, Diseases, Pregnancy in Diabetics, Infant, Diabetic Mother, Hypoglycemia
- Trial name
- DIMOHN (NCT00994149)
- Testing
- Diazoxide, Ora-plus
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Saskatchewan
Diabetes Mellitus, Type 2, Diabetic Nephropathies
Cholesterol Metabolism in Plasma and Interstitial Fluid Among Subjects Undergoing Hemodialysis.
Because the atherosclerosis process partly occur in the intercellular space of the vessel wall, the determination of the constitution of lipoproteins in the interstitial fluid may expand the knowledge about the atherosclerosis…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Nephropathies, Chronic Kidney Diseases
- Trial name
- NCT03921216
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska University Hospital
Macrosomia, Fetal
Improving Patient Understanding of Macrosomia
The purpose of this study is to evaluate the effectiveness of a graphic based education tool on patient knowledge of macrosomia through the use of a survey and to evaluate knowledge at 1-2 weeks after initial review of the…
- Trial name
- NCT06281301
- Testing
- education tool, no additional information
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Diabetes, Diabetic Kidney Disease
Immune System in Diabetic Kidney Disease
Diabetes is a chronic condition marked by long-term elevated blood glucose levels. There are more types of diabetes; the majority of patients have type 1 or type 2 diabetes.
- Conditions
- Diabetes, Diabetic Kidney Disease, Complement System
- Trial name
- KID-CODE (NCT07292493)
- Where
- Slovenia
- Volunteers
- 90 people
- Sponsor
- University Medical Centre Ljubljana
Diabetic Nephropathy, Diabetes Mellitus
Mechanisms of Diabetic Nephropathy in Ecuador
The prevalence of diabetes mellitus (DM) is increasing worldwide, suggesting that 45% of diabetics are undiagnosed. DM induces a kidney disease called diabetic nephropathy (DN) which is the largest single cause of end-stage renal…
- Conditions
- Diabetic Nephropathy, Diabetes Mellitus, Kidney Diseases, Diabetic Kidney Disease
- Trial name
- NCT02237352
- Where
- Ecuador
- Volunteers
- 10,064 people, healthy volunteers welcome
- Sponsor
- Universidad Estatal de Milagro
Chronic Kidney Disease, Diabetic Kidney Disease
A Trial to Learn More About How BAY2327949 Works and How Safe it is in Patients Whose Kidneys Are Damaged Due to High Blood Sugar Levels or High Blood Pressures, and With a Further Disease of the Heart or the Blood Vessels.
In people with type 2 diabetes (T2D), the body makes insulin, but cannot use it well. This results in high blood sugar levels causing damage to the blood vessels inside the kidneys.
- Trial name
- ASSESS-CKD (NCT04661917)
- Testing
- BAY2327949
- Where
- 36 sites in Austria, Denmark and 5 more
- Sponsor
- Bayer
Diabetic Kidney Disease
The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease
Diabetic kidney disease (DKD) is a devastating complication of diabetes, that in it's worst form, can lead to early cardiovascular death or kidney failure.
- Trial name
- NCT01847313
- Testing
- Liraglutide
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Karl Neff
Nervous System, Diabetic Kidney Disease
Mechanisms of Diabetic Kidney Disease in American Indians
Background: An ongoing study is looking at American Indians who have kidney problems caused by type 2 diabetes. Kidney disease due to type 2 diabetes is a major problem in American Indians.
- Conditions
- Nervous System, Diabetic Kidney Disease, Diabetes Mellitus, Type 2
- Trial name
- NCT01878045
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus Pregnancy
Glycemic Control and Iron Status in Diabetic Pregnancies - a Study of New Markers
This is an observational study at the Obstetrical outpatient clinic at Stavanger University Hospital. The main goal is to compare the current marker of glycemic control (glycated hemoglobin A1c, HbA1c) with glycated albumin in…
- Trial name
- NCT03330951
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Helse Stavanger HF
Diabetic Nephropathy
Expression Analysis of Urinary Exosome in Type 2 Diabetic Nephropathy and Evaluation of Its Clinical Diagnostic Value
Expression analysis of urinary exosome miR-142-3p in type 2 diabetic nephropathy and evaluation of its clinical diagnostic value
- Trial name
- NCT06097351
- Testing
- Grouping based on previous laboratory results, no intervention.
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Yipeng Liu
Diabetic Nephropathy, Hypertensive Nephropathy
Ayurvedic Management of Chronic Kidney Disease
The purpose of this study is to determine the effect of multi-dimentional ayurvedic treatment in the patients of various types of chronic kidney disease.
- Trial name
- NCT02477163
- Testing
- Ayurveda treatment
- Where
- India
- Volunteers
- 521 people
- Sponsor
- J.S. Ayurveda College
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention IN Gestational Diabetes (LIVING)
Investigators have taken the learning from various programs to develop a new lifestyle program (LIVING) that has a high probability of being feasible, acceptable and cost-effective in the South Asian context for women with prior…
- Trial name
- LIVING (NCT03305939)
- Testing
- Life style Intervention
- Where
- 20 sites in Bangladesh, India and 1 more
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- The George Institute
Sars-CoV2, Covid-19
COPE - COVID-19 in Pregnancy and Early Childhood
Purpose: The emergence of a new coronavirus SARS-CoV-2 causing a novel infection in the human race resulting in a world-spanning pandemic came as a surprise and at a tremendous cost both for individual human lives as well as for…
- Conditions
- Sars-CoV2, Covid-19, Pregnancy Complications, Pregnancy Preterm
- Trial name
- COPE (NCT04433364)
- Testing
- biological samples, questionnaires and interviews
- Where
- 27 sites in Sweden
- Volunteers
- 3,834 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Proteinuric Kidney Disease, Diabetic Nephropathy
Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease
Primary Hypothesis: Aldosterone breakthrough will occur at a far lower frequency during renin inhibition (0-10% over 9 months), alone or in combination with an ARB, compared to conventional ARB therapy (35-45% over 9 months).
- Conditions
- Proteinuric Kidney Disease, Diabetic Nephropathy, Hypertensive Nephrosclerosis, IgA Nephropathy
- Trial name
- NCT01129557
- Testing
- Aliskiren, Valsartan
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Columbia University
Type 1 Diabetes Mellitus, Diabetic Retinopathy
The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye.
The purpose of this study is to evaluate the potential benefits of 145 mg of daily fenofibrate in adults with type 1 diabetes mellitus and pre-existing non-proliferative diabetic retinopathy.
- Conditions
- Type 1 Diabetes Mellitus, Diabetic Retinopathy, Diabetic Nephropathies
- Trial name
- FAME 1 EYE (NCT01320345)
- Testing
- Fenofibrate
- Where
- 24 sites in Australia, Hong Kong and 2 more
- Volunteers
- 412 people
- Sponsor
- University of Sydney