Clinical trials: Pregnancy in Diabetic
Gestational Diabetes Mellitus in Pregnancy
First Trimester Prediction of Gestational Diabetes Mellitus by Continuous Glucose Monitoring.
Gestational diabetes mellitus (GDM) is the most common complication of pregnancy, with an incidence rate of 10-15% [1]. Common risk factors for GDM are increased maternal age and weight and as a consequence of women delaying…
- Trial name
- GLUCO-GCM (NCT06874907)
- Testing
- Glucose monitoring
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Diabetic Nephropathy
Combined Diabetes-Renal Multifactorial Intervention In Patients With Advanced Diabetic Nephropathy (ADN)
The purpose of this study is to compare the progression of kidney disease in subjects with Diabetes mellitus type 2 and Advanced Diabetic Nephropathy treated by routine follow-up as a general care and in subjects treated by…
- Trial name
- NCT00708981
- Testing
- Multifactorial Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Cook County Health
Diabetes During Pregnancy
Fueling Labor: Protein Supplementation for Intrapartum Glucose Control
The goal of this study is to learn if high-protein drinks during labor can improve blood sugar control in pregnant women with insulin-treated diabetes.
- Trial name
- NCT07571343
- Testing
- High-Protein Beverage (Genius Gourmet Sparkling Protein Water), Standard Clear Liquid Diet, Continuous Glucose Monitoring (Abbott Freestyle Libre)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical College of Wisconsin
Type 1 Diabetes Mellitus, Diabetic Nephropathy
Impact of c242T Polymorphism of p22phox in Diabetic type1 Nephropathy
The physiopathology of diabetic nephropathy (DN) is unclear. To investigate risk factor, the investigators choose to look about some oxidative stress genes. Today a one-gene explanation is not really possible.
- Trial name
- NEPHRODIANOX (NCT01371955)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Grenoble
Renal Insufficiency, Chronic
The Incretin Effect in Patients With Kidney Impairment
The current study explores the incretin effect; a central mechanism of sugar metabolism. People with type 2 diabetes have a markedly reduced incretin effect, while the incretin effect never has been studied in patients with…
- Trial name
- UREMINC (NCT01327378)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Gestational Diabetes Mellitus (GDM), Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled
The Effect of TUBER Recommendations and the DASH Diet on Blood Parameters in Patients With Gestational Diabetes
The aim of this clinical trial was to examine the effects of the Turkish Nutrition Guide Recommendations Diet and the DASH Diet on blood sugar, blood pressure, and biochemical parameters in patients with gestational diabetes.
- Trial name
- NCT07101406
- Testing
- Türkiye Nutrition Guideline Diet, DASH Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Kardelen Kandemir
Diabetic Kidney Disease
The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease.
The goal of this clinical trial is to to investigate whether the drug R3R01 has a beneficial effect on the amount of protein excreted in the urine in adult patients (above 18 years of age) with type 2 diabetes and resulting…
- Trial name
- Kidney ABC (NCT06600412)
- Testing
- R3R01
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- River 3 Renal Corp.
Diabetic Nephropathy, Type 2 Diabetes Mellitus
A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria
The purpose of this study is to evaluate the effect of treatment with CCX140-B on urinary albumin excretion in subjects with type 2 diabetes mellitus and albuminuria, as well as to study the safety and efficacy of the medication…
- Trial name
- NCT01440257
- Testing
- CCX140-B
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Amgen
Healthy Volunteers
FIH Ph 1 Study of TRPC5 Channel Inhibitor GFB-887 in Healthy Subjects
The study will comprise primarily a single-ascending dose (SAD) escalation component.
- Trial name
- NCT03970122
- Testing
- GFB-887
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Goldfinch Bio, Inc.
Glomerulonephritis, IGA, Glomerulonephritis, Membranous
Application of Hyperspectral Imaging in the Diagnosis of Glomerular Diseases
Morning urine samples of patients with IgA nephropathy, idiopathic membranous nephropathy, diabetic nephropathy, and minimal degenerative nephropathy confirmed by renal needle biopsy in our hospital from November 2020 to January…
- Conditions
- Glomerulonephritis, IGA, Glomerulonephritis, Membranous, Diabetic Nephropathies, Nephrosis, Lipoid
- Trial name
- NCT05797051
- Testing
- Microscopic hyperspectral imaging system
- Volunteers
- 80 people
- Sponsor
- Qianfoshan Hospital
Type 1 Diabetes, Nephropathy, Diabetic
SGLT2 Adjunct in T1D
Effect of Sodium-Glucose Cotransporter (SGLT) 2 Inhibitors on Diabetic Nephropathy Progression in Adolescents with Type 1 Diabetes Mellitus
- Trial name
- NCT07591077
- Testing
- Empagliflozin (EMPA)
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Gestational Diabetes Mellitus in Pregnancy, Anxiety
Effects of Rhythm-Based Music on Pregnancies With Gestational Diabetes
This study is for people who have gestational diabetes, a type of diabetes that happens during pregnancy. People with gestational diabetes may feel more anxious than others during pregnancy.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Anxiety, Blood Sugar; High
- Trial name
- NCT06970886
- Testing
- Rhythm-Based Music Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Esin Ceber Turfan, Professor
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Olmesartan Medoxomil and Diabetic Nephropathy
Evaluation of several olmesartan dosages compared to losartan on proteinuria, renal function and inflammatory markers in patients with diabetic nephropathy
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Proteinuria, Renal Disease
- Trial name
- NCT00362960
- Testing
- Olmesartan medoxomil, Losartan
- Where
- 27 sites in Czechia, Estonia and 5 more
- Volunteers
- 300 people
- Sponsor
- Sankyo Pharma Gmbh
Chronic Kidney Disease
Does Thiazolidinedione Therapy Improve Endothelial Function and Preserve Renal Function
The hypothesis of the current proposal is that chronic pioglitazone therapy will result in improved endothelial function, decreased inflammation, and preservation of renal function in patients with CKD but without diabetes.
- Trial name
- NCT00586261
- Testing
- Pioglitazone, Nitroglycerin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2, Diabetic Kidney Disease
Renohemodynamic Effects of Combined empagliflOzin and LosARtan
Worldwide, diabetic kidney disease (DKD) is the most common cause of chronic and end stage kidney disease. In parallel with the ever-increasing rates of obesity and type 2 diabetes (T2D), the incidence of DKD is expected to…
- Trial name
- RECOLAR (NCT04238702)
- Testing
- Empagliflozin 10 MG, Losartan 50Mg Tab
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Amsterdam UMC, location VUmc
Renal Insufficiency, Chronic, Diabetic Nephropathy Type 2
Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy
NephroNet proposes to examine whether combining Spironolactone with maximal RAAS blockade will further reduce urinary protein at one year and whether prolonged therapy (24 months) is able to slow the decline in GFR.
- Trial name
- MRA-ACE (NCT03502031)
- Testing
- Renin-Angiotensin (RAAS) alone, Renin-Angiotensin (RAAS) blockers in combination with Spironolactone
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- James A. Tumlin, MD
Essential Hypertension, Type 2 Diabetes
Sacubitril/Valsartan Treats Patients With Essential Hypertension and Type 2 Diabetic Nephropathy
This study aims to compare the efficacy and safety of Sacubitril/Valsartan versus Valsartan in patients with essential hypertension and type 2 diabetic nephropathy over a 12-week treatment period, including two treatment groups…
- Conditions
- Essential Hypertension, Type 2 Diabetes, Nephropathy
- Trial name
- Hyper-Save (NCT06501651)
- Testing
- Sacubitril/Valsartan, Valsartan
- Where
- China
- Volunteers
- 297 people
- Sponsor
- Sichuan Academy of Medical Sciences
Diabetic Kidney Disease
Evaluate the Role of Soleus Muscle Exercise in Glycaemic Control in Diabetic Kidney Disease Patients
Evaluate the role of Soleus muscle exercise in management diabetic kidney disease
- Trial name
- NCT06120569
- Testing
- Soleus ms exercise
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nora Hussein Kamal
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
ESRD, Diabetes
IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions (PEN vs Dianeal) in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD)and Automated Peritoneal Dialysis (APD) patients leads…
- Trial name
- Impendia (NCT00567398)
- Testing
- Dianeal, Physioneal, Extraneal
- Where
- 16 sites in Australia, Canada and 1 more
- Volunteers
- 43 people
- Sponsor
- Vantive Health LLC