Clinical trials: Pregnant
Lower Urinary Tract Symptoms
Connective Tissue Manipulation on Pelvic Floor Muscle Functions in Children
Lower urinary tract dysfunction (LUTD) is a disease group with subgroups that make up 40% of the patients were admitted to the pediatric urology clinic.
- Trial name
- NCT05824429
- Testing
- Urotherapy, Diaphragmatic Breathing Exercises, PFM Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute
Klinefelter Syndrome, XXY Syndrome
Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome
The purpose of this study is to determine if testosterone replacement therapy leads to changes in psychological factors and/or motor skills in adolescent males with 47,XXY (also called Klinefelter syndrome).
- Trial name
- TestoXXY/KS (NCT01585831)
- Testing
- Testosterone gel 1%
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Colorado, Denver
Nephrolithiasis, Renal Calculi
Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of Renal Calculi
This study is being carried out in patients with kidney stones measuring between 1 and 2 centimeters. Kidney stones are common in Pakistan and can cause severe pain, infection, and repeated hospital visits.
- Trial name
- NCT07261995
- Testing
- Extracorporeal Shock Wave Lithotripsy (ESWL), Retrograde Intrarenal Surgery (RIRS)
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Ziauddin Hospital
Urinary Stones
Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)
A pivotal study to evaluate the safety and effectiveness of Applaud Acoustic Enhancer when used in conjunction with conventional ureteroscopic laser lithotripsy (URS-LL) in the treatment of subjects with urinary stones.
- Trial name
- AEROLITH (NCT04563039)
- Testing
- Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
- Where
- 23 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Avvio Medical
Renal Impairment
Assessment of Renal Function by Multiparametric MRI
Metabolic syndrome is a collection of conditions that affect at least three of the following five criteria: abdominal obesity, high blood pressure, high fasting glucose levels, high triglyceride levels, and low levels of…
- Trial name
- NCT06407375
- Testing
- mpMRI
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Virginity, Genital Diseases, Female
Transrectal and 3D Transabdominal Ultrasound Compared to Vaginoscopy in Diagnosing Virgins With Genital Lesions
This study is to compare the feasibility and test performance of different 3D pelvic ultrasound and Transrectal ultrasound in the detection of local lesions in the uterus , cervix and vagina compared to the final diagnosis…
- Conditions
- Virginity, Genital Diseases, Female, Diagnoses Disease
- Trial name
- NCT04858919
- Testing
- 3D transabdominal ultrasound, transrectal ultrasound, vaginoscopy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Placenta Accreta, Cesarean Hysterectomy
Conservative Treatment of PAS With or Without IIL
In the current study, the investigators aimed to compare the benefits of internal iliac ligation in placenta accreta spectrum
- Conditions
- Placenta Accreta, Cesarean Hysterectomy, Pelvic Devascularization
- Trial name
- PASIIL (NCT05232981)
- Testing
- Ligation of the bilateral internal iliac arteries, Shehat's technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Vagina Disease, Diagnosis
Feasibility of the Oricol™ Sampling Device to Retrieve Vagina Mucus (Wall) Samples for Genomic & Epigenetic Analysis.
Primary Objective The primary objective is to explore the feasibility of collecting a vaginal sample using the OriCol™ Sampling Device. Secondary Objectives The study has secondary objectives to assess: 1.
- Trial name
- Ellele-01 (NCT05709119)
- Testing
- Quantification of human DNA retrieved and DNA fragmentation profile.
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Origin Sciences
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Bladder Cancer, Muscle Invasive Bladder Cancer
Avelumab and Radiation in Muscle-Invasive Bladder Cancer
This research study is studying the effects of adding a certain type of immunotherapy to standard bladder-directed radiation as a treatment for muscle-invasive urothelial carcinoma of the bladder.
- Trial name
- NCT03747419
- Testing
- Avelumab, Radiation
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Dana-Farber Cancer Institute
Pertussis, Pregnancy Related
Seroprevalence of Bordetella Pertussis Antibodies and Anti-pertussis Antibody Response After a Single Dose of Tdap in Pregnant Thai Women
This study evaluated the seroprevalence of Bordetella pertussis antibodies and anti-pertussis antibody response after a single dose of reduced-antigen, combined diphtheria, tetanus, and acellular pertussis vaccine (Tdap) in…
- Trial name
- NCT03498300
- Testing
- Tdap vaccine
- Where
- Thailand
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Premature Labor
Pharmacokinetics (PK) and Modeling of Betamethasone Therapy in Threatened Preterm Birth
Respiratory distress syndrome (RDS) is a life-threatening condition for premature neonates. Antenatal glucocorticoids have been used clinically in women with threatened preterm birth to accelerate lung maturation for more than 40…
- Trial name
- NCT02793700
- Where
- 2 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT05080907
- Testing
- Observational
- Where
- 7 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Spinal Cord Injuries, Neurogenic Bladder
Intravesical LGG VS Saline Bladder Wash RCT
This is the first ever comparative effectiveness study of an antibiotic-sparing novel self-management intervention to prevent complicated urinary tract infection (UTI).
- Trial name
- NCT05230511
- Testing
- Lactobacillus RhamnosusGG, Saline bladder wash
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medstar Health Research Institute
Hematuria, Cystoscopy
Bladder EpiCheck European Haematuria Study
The goal of this observational study is to further validate the sensitivity and specificity of Bladder EpiCheck in primary detection of urothelial carcinoma in participants aged 45 years or older presenting with haematuria…
- Conditions
- Hematuria, Cystoscopy, Urothelial Carcinoma Bladder, Urothelial Carcinoma of the Renal Pelvis and Ureter
- Trial name
- NCT06818136
- Testing
- Bladder EpiCheck
- Where
- 5 sites in United Kingdom
- Volunteers
- 800 people
- Sponsor
- Nucleix Ltd.
Stress Urinary Incontinence
Comparison of Efficacy and Side Effects Between the Obtryx and Solyx Band With 5-year Follow-up.
Boston2018 post-market clinical study is a prospective, randomized, non-inferiority study to assess the efficacy and adverse events of the Solyx™ Single Incision Sling (SIS) System compared to the gold-standard Obtryx™ II Sling…
- Trial name
- NCT03916471
- Testing
- Solyx™ SIS System, Obtryx™ II System (Halo)
- Where
- Spain
- Volunteers
- 166 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
High Risk Pregnancy
Sildenafil Citrate Added to Low Molecular Weight Heparin and Low Dose Aspirin in High-risk Pregnancy
Anticoagulant therapy is indicated during pregnancy for the prevention and treatment of venous thromboembolism, systemic embolism in patients with mechanical heart valves and, in combination with aspirin, for the prevention of…
- Trial name
- NCT04110444
- Testing
- Sildenafil
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Cervical Cancer, Hpv
PopSci CHW4CervixHealth
Phase I: Validating self-collection kit by comparing their results with clinical Pap smear results in a cohort of 20 patients. Phase II: Evaluate the feasibility and acceptability of the CHW4CervicalHealth: Use of a…
- Conditions
- Cervical Cancer, Hpv, Human Papilloma Virus, HPV Infection
- Trial name
- NCT07336134
- Testing
- Evalyn® Brush, Copan Floqswab, CHW4CervicalHealth
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cardiac Surgery
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.
To date, no pharmacological agents are proven efficacious in treating perioperative AKI. There is a strong biological rationale for the administration of amino acid in the management of patients at risk of AKI with increases in…
- Trial name
- PROTection (NCT03709264)
- Testing
- Amino Acids
- Where
- 22 sites in Croatia, Italy and 1 more
- Volunteers
- 3,511 people
- Sponsor
- Università Vita-Salute San Raffaele