Clinical trials: Pregnant Individuals
Cardiovascular Diseases, Renal Disease
OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals
Cardiovascular disease (CVD) causes a quarter of all deaths in the United Kingdom (UK). This is the single biggest area where the National Health Service (NHS) can save lives by detecting and treating risk factors early.
- Conditions
- Cardiovascular Diseases, Renal Disease, Metabolic Disease, Pulmonary Disease
- Trial name
- OPTIMISE (NCT06444711)
- Testing
- NICE guidance
- Where
- United Kingdom
- Volunteers
- 138 people
- Sponsor
- University of Leeds
Neurogenic Bladder, Spinal Cord Injuries
Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections
Participants will undergo daily gentamicin bladder instillations to determine if its use will reduce the rate of symptomatic urinary tract infections (UTIs) as well as the use of oral and intravenous antibiotics in adults with…
- Trial name
- NCT03931408
- Testing
- Gentamicin Sulfate, No instillation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Urinary Incontinence
Effects of Group-based and Individual Pelvic Floor Muscle Training on Elderly Individuals With Urinary Incontinence
The purpose of this study is to asses the effects of 12-week group-based and individually planned pelvic floor muscle training on individuals aged 65 and over with urinary incontinence.
- Trial name
- NCT06547580
- Testing
- Group-based PFMT, Individualized PFMT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
PCOS (Polycystic Ovary Syndrome)
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires.
This exploratory study investigates the impact of fertility treatments on symptoms of irritable bowel syndrome (IBS) in women. Specifically, the study focuses on two groups: Women with polycystic ovary syndrome (PCOS) who are…
- Trial name
- FIBS (NCT07533968)
- Testing
- questionnaires
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Low Back Pain, Urinary Incontinence
Investigation of the Effects of Stabilization Exercises and Pelvic Floor Muscle Training on Pain and Urinary Parameters in Individuals With Chronic Low Back Pain With Urinary Incontinence
The research will be done with people with urinary incontinence and low back pain. 3 groups of volunteer participants will be formed. The groups were planned as study group, classical application group and control group.
- Trial name
- NCT05666427
- Testing
- Pelvic floor muscle training combined with stabilization exercises, Pelvic floor muscle training
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Kidney Failure, Chronic
Patient-Provider Trust Among Individuals With End-Stage Kidney Disease
This study will examine communication and trust between patients in the kidney transplant process and their health care providers.
- Trial name
- NCT00075036
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Kidney Failure, Chronic
Sodium-Endothelial Function-CKD Study
Heart disease and stroke, known as cardiovascular disease, are major causes of death in people with chronic kidney disease. Abnormalities of a metabolic pathway called the "L-arginine-nitric oxide" pathway are thought to be…
- Trial name
- NCT00141622
- Testing
- Slow sodium
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- St George's, University of London
Chronic Kidney Disease (CKD)
Community-based Screening of Chronic Kidney Disease (CKD) and Measure the Impact of Health Education
Background: Chronic kidney disease (CKD) is a global public health concern. Currently 10-16% adults are affected with CKD. Adult individuals from low- and middle-income countries are at higher risk of developing CKD and End stage…
- Trial name
- NCT04094831
- Testing
- Health education
- Where
- Bangladesh
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Respiratory Syncytial Virus (RSV)
Evaluating ABRYSVO Maternal Vaccine Effectiveness Among Infants
To generate critical evidence to support vaccine policy and implementation, Pfizer will collaborate with Kaiser Permanente Northern California (KPNC) to study the vaccine effectiveness (VE) of ABRYSVO vaccination during pregnancy…
- Trial name
- NCT07249320
- Testing
- ABRYSVO
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Pregnant Individuals, Obesity & Overweight
Gestational Response, Outcomes, and Weight After GLP-1 Use
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes.
- Conditions
- Pregnant Individuals, Obesity & Overweight, Gestational Weight Gain
- Trial name
- GROW (NCT07743567)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Pregnancy Related, Food Insecurity
Nourishing Beginnings: Addressing Food Insecurity During Pregnancy
This is a pilot project designed to test the feasibility of implementing a community health worker (CHW)-led intervention to improve nutritious food access and consumption among pregnant people and to evaluate the effectiveness…
- Conditions
- Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications
- Trial name
- NCT05341960
- Testing
- Food Delivery, Financial Support
- Where
- 2 sites in United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Kidney Stone, Urolithiasis, Calcium Oxalate
Heterozygous Individuals for AGXT and Kidney Stones
This study seeks to examine the effects of a heterozygous mutation of the AGXT gene in a stone forming population on endogenous oxalate production.
- Trial name
- NCT04430426
- Testing
- Controlled Diet
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Turner Syndrome, Post-menarcheal Adolescents
Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
Background: Turner Syndrome, galactosemia, and premature ovarian insufficiency are all conditions that may make it very hard or impossible for a person to become pregnant and have their own child.
- Conditions
- Turner Syndrome, Post-menarcheal Adolescents, Ovarian Disfunction, Galactosemia
- Trial name
- NCT04948658
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Interstitial Cystitis, Chronic Prostatitis
Chronic Pelvic Pain Study of Individuals With Diagnoses or Symptoms of Interstitial Cystitis and/ or Chronic Prostatitis
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder Syndrome (PBS) in men and…
- Trial name
- MAPP-EP (NCT01098279)
- Where
- 8 sites in United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Primary Amenorrhoea, Hypothalamic Amenorrhoea
Pubertal Induction in Individuals With Hypogonadism
The investigators wish to explore the variability of uterine, breast and bone outcome markers as surrogates to assess the adequacy of exogenous oestrogen replacement in individuals with hypogonadism.
- Conditions
- Primary Amenorrhoea, Hypothalamic Amenorrhoea, Hypogonadotrophic Hypogonadism, Hypopituitarism
- Trial name
- NCT02871986
- Testing
- Routine transdermal oestrogen patch
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Renal Cancer, Von Hippel Lindau
Phase II Study of Vandetanib in Individuals With Kidney Cancer
This study will examine the effectiveness of an investigational drug called ZD6474 (also known as vandetanib or ZACTIMA). Vandetanib is an experimental drug that is designed to prevent the growth and development of new blood…
- Trial name
- NCT00566995
- Testing
- ZACTIMA (Vandetanib) (ZD6474)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Uterine Cervical Neoplasms, HPV Testing
Human Papillomavirus (HPV) Self-Sampling Options to Promote Equity
This study is testing a new way to help people who are unhoused get screened for cervical cancer. Cervical cancer can often be prevented if it is found early.
- Conditions
- Uterine Cervical Neoplasms, HPV Testing, Pap Smear
- Trial name
- HOPE (NCT07214506)
- Testing
- Human papillomavirus Self-collection, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Cervical Cancer
HPV Self-sampling to Improve Access to Cervical Cancer Screening for Persons With HIV and/or Underserved Individuals
The objective of this study is to evaluate self-collection of vaginal samples for HPV testing as an alternative cervical cancer screening strategy for persons with HIV and/or limited access to care.
- Trial name
- ACCESS (NCT05528237)
- Testing
- Flocked swab paired with Roche Cobas 4800
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington
Treponema Pallidum, Treponema Pallidum Infection
This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.
This study will evaluate the clinical performance of two investigational diagnostic kits developed by ALPCO: the Syphilis-T CLIA Kit and the Syphilis-NT CLIA Kit.
- Conditions
- Treponema Pallidum, Treponema Pallidum Infection, Syphilis Infection, Serum
- Trial name
- NCT07089836
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Stroke, Urinary Incontinence
The Relationship Between Urinary Incontinence and Motor Symptoms
There is no study in the literature examining the relationship between urinary incontinence and motor symptoms in individuals with stroke.
- Conditions
- Stroke, Urinary Incontinence, Motor Skills Disorders
- Trial name
- NCT06333119
- Testing
- modified rankin scale
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pinar Yasar