Clinical trials: Pregnant With Complication
HPV Infection, Cervical Cancer
Effector and Memory Immune Responses to HPV Vaccination in Vietnamese Women Post Virus Exposure
A Study to evaluate if the 3 dose extended schedule (0-6-18 months) for the HPV vaccine Gardasil-9 provide similar immune responses and short term protection against HPV infection compared to the regular 3 dose schedule (0-2-6…
- Conditions
- HPV Infection, Cervical Cancer, Anogenital Cancer, Anogenital Warts
- Trial name
- HPV9vxFSW (NCT06681636)
- Testing
- Human papillomavirus 9-valent vaccine, Recombinant
- Where
- 3 sites in Australia, Vietnam
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Hygiene and Epidemiology, Vietnam
Morning Sickness, Pregnancy Early
The Effect of Scent on Pregnancy Induced Nausea, Vomiting, and Quality of Life
This study evaluates the effects of essential oils on nausea, vomiting, and quality of life scores among pregnant women. Participants will receive either an essential oil roll-on product or a placebo product to apply to their…
- Trial name
- NCT03513536
- Testing
- Citrus-Based Aromatherapy, Mint-Based Aromatherapy, Spice-Scented Aromatherapy
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Melanoma, Non Small Cell Lung Cancer
Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors
AI-061 is a co-formulation drug product (DP) consisting of 1:1 ratio mix of AI-025, an anti-PD-1 antibody, and ONC-392, an anti-CTLA-4 antibody.
- Conditions
- Melanoma, Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, High Grade Serous Adenocarcinoma of Ovary
- Trial name
- PRESERVE-009 (NCT05858736)
- Testing
- AI-061
- Where
- 5 sites in Australia
- Volunteers
- 18 people
- Sponsor
- OncoC4, Inc.
Stress Urinary Incontinence
Evaluation Of The Ability Of Fesoterodine To Increase Urethral Pressure In Stress Urinary Incontinence Patients
The hypothesis under evaluation is that fesotorodine may provide clinical benefit in the treatment of the condition of stress urinary incontinence
- Trial name
- NCT01042236
- Testing
- Fesoterodine
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Pfizer
Kidney Calculi
Paravertebral Block Versus Epidural Anesthesia for Percutaneous Nephrolithotomy
This prospective, randomized study is aimed to assess the efficacy and safety of paravertebral block compared to epidural anesthesia for percutaneous nephrolithotomy.
- Trial name
- PVB (NCT03018899)
- Testing
- paravertebral block, epidural anesthesia
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Huazhong University of Science and Technology
Urinary Incontinence
Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy
I. Specific Aims Pelvic organ prolapse is a common and distressing condition that is frequently associated with stress urinary incontinence (SUI) and often requires surgical repair.
- Trial name
- NCT00934999
- Testing
- Burch urethropexy, Synthetic mid-urethral sling (TVT)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Mayo Clinic
Endometriosis, Ovarian Cysts
Danazol Treatment in Endometriosis Women Before IVF
The purpose of this study is to determine whether pre-treatment with danazol for at least 4 months before controlled ovarian hyperstimulation for IVF cycles improves pregnancy rate.
- Conditions
- Endometriosis, Ovarian Cysts, Infertility
- Trial name
- NCT01779232
- Testing
- Danazol
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Endometriosis
A Randomized, Placebo-controlled, Double-blind Study of KLH-2109 in Patients With Endometriosis (2)
The purpose of this study is to evaluate the efficacy and safety of KLH-2109 in patients with endometriosis.
- Trial name
- NCT01533532
- Testing
- KLH-2109
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Infertility, Monofollicular Development
Low-dose Gonal-f® in Ovulation Induction
This is a prospective, multicenter, open-label, comparative and parallel-group study of ovulation induction evaluating tailoring of Recombinant follicle stimulating hormone (FSH) treatment using the Gonal-f® prefilled pen in…
- Trial name
- LoGo (NCT01871532)
- Testing
- Gonal-f®
- Where
- 10 sites in Ireland, United Kingdom
- Volunteers
- 24 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Postpartum Depression
Postpartum Thyroid Measures and Mood
Women with abnormal serum thyroid antibody levels or abnormal TSH and/or T4 values are more likely than their normal counterparts to have higher scores on a common postpartum depression screening test.
- Trial name
- NCT00565032
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Bladder Cancer
Selenium in Preventing Cancer Recurrence in Patients With Bladder Cancer
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of selenium may keep bladder cancer from growing or coming back.
- Trial name
- SELEBLAT (NCT00729287)
- Testing
- selenium
- Where
- Belgium
- Volunteers
- 276 people
- Sponsor
- KU Leuven
Benign Prostatic Hyperplasia, Overactive Bladder
The Combined Effect of Intravesical Botox Injections and HoLEP Surgery in Treating Benign Prostatic Hyperplasia and Overactive Bladder
Benign prostatic hyperplasia (BPH) is the most common benign neoplasm in men. Almost 90% of men in their 70s report lower urinary tract symptoms related to BPH.
- Trial name
- NCT05393921
- Testing
- Intravesical Botox injection
- Where
- 3 sites in United States
- Sponsor
- University Hospitals Cleveland Medical Center
Heart Failure, Congestive
Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure
Different doses of relaxin will be compared to placebo to determine efficacy and safety for the treatment of patients hospitalized with acute heart failure
- Trial name
- RELAX-AHF (NCT00520806)
- Testing
- Relaxin
- Where
- 3 sites in United States, Israel
- Volunteers
- 1,161 people
- Sponsor
- Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Hemorrhage Postpartum
Sublingual Misoprostol to Reduce Blood Loss During Elective Cesarean Delivery
Sublingual Misoprostol to Reduce Blood Loss During Elective Cesarean Delivery : A Randomized Controlled Trial
- Trial name
- NCT03140033
- Testing
- Misoprostol Oral Tablet, Ranitidine Oral Tablet
- Where
- Egypt
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Renal Insufficiency, Chronic, Glaucoma
Intraocular Pressure and Hemodialysis Midwestern Brazil
Objective: To evaluate the variation in intraocular pressure in patients with chronic kidney disease, according to the time interval between hemodialysis sessions and to the influence of weight and blood pressure on intraocular…
- Trial name
- EHPIOBRAZIL (NCT02405884)
- Testing
- Kowa HA-2 Perkins applanation tonometer.
- Volunteers
- 39 people
- Sponsor
- VER Excelência em Oftalmologia
Pathogenesis, Acute Kidney Injury
Perioperative Mechanism of Acute Kidney Injury in Cardiovascular Surgery
Continuous observation of acute renal injury after cardiac surgery, at the same time retention of blood samples, to test indicators，and to select the research route from the clinical actual test results .
- Conditions
- Pathogenesis, Acute Kidney Injury, Cardiac Surgery
- Trial name
- NCT03557047
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
46, XY DSD
Phenotypic and Genotypic Characterisation of a Large, Multicentre Italian Cohort of 46, XY DSD Patients
Observational exploratory study of a cohort of pediatric and adolescent patients diagnosed with DSD karyotype 46,XY, a rare congenital clinical condition characterized by a disharmonic development between chromosomal sex, gonadal…
- Trial name
- NCT06723938
- Where
- 4 sites in Italy
- Volunteers
- 520 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Ischemic Stroke, Contrast-induced Nephropathy
Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT).
- Conditions
- Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
- Trial name
- NCT07546448
- Testing
- No intervention (observational cohort study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Endometriosis
Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery
The purpose of the study is to compare the recurrence of endometriotic cyst in patients taking Dienogest or Microgynon after conservative surgery.
- Trial name
- NCT02385448
- Testing
- Dienogest, Microgynon
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Human Papillomavirus Infection, Cervical Cancer
Clinical Evaluation of Detection of High Risk HPV in Urine
Cervical cancer is one of the most common tumors in women, which seriously threatens women's life quality and safety. Human papilloma virus (HPV) infection is the most common cause of cervical cancer.
- Conditions
- Human Papillomavirus Infection, Cervical Cancer, Human Papilloma Virus, Negative for Intraepithelial Lesion or Malignancy
- Trial name
- Urine-hrHPV (NCT05210348)
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital