Clinical trials: Prehabilitation
Colon Cancer, Postoperative Complications
Multidisciplinary Prehabilitation and Postoperative Rehabilitation in Patients Undergoing Resection of Colon Cancer
ONCOFIT is a randomized clinical trial with a two-arm parallel design aimed at determining the influence of a multidisciplinary prehabilitation + postoperative program on post-surgery complications in patients undergoing…
- Trial name
- ONCOFIT (NCT05379205)
- Testing
- Prehabilitation program (4 week before the surgery), Postoperative program (12 week after the surgery), Usual Care
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad de Granada
Anterior Cruciate Ligament Injury, Knee Joint
ACL Prehabilitation and Functional Outcomes
Anterior cruciate ligament (ACL) rupture is a common knee injury that frequently requires surgical reconstruction and extensive postoperative rehabilitation.
- Trial name
- ACL Prehab fun (NCT07627724)
- Testing
- Preoperative Prehabilitation Program, Standard Preoperative Care
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Beni-Suef University
Thoracic Surgery
Surgical Prehabilitation on Autonomic Nervous System (TUNE)
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV).
- Trial name
- TUNE (NCT06398301)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Breast Cancer
Prehabilitation for Breast Cancer Surgery
Prehabilitation for women diagnosed with breast cancer is commonly not part of the clinical pathways as little time (usually a few days) is left between diagnosis and surgery.
- Trial name
- NCT05216302
- Testing
- Group-based Nordic Walking Exercise Program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Raquel Sebio
Rectal Cancer, Low Anterior Resection Syndrome
Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Low Anterior Resection Syndrome.
Patients with sphincter saving procedures of rectal cancer usually experience intestinal dysfunction, including difficulty emptying the bowel and faecal incontinence, leading to a detriment in the quality of life.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Faecal Incontinence
- Trial name
- PRELARS (NCT04612569)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Esophageal Cancer, Gastroesophageal Junction Cancer
STRENGTH Expansion
Patients seen in the EGMDC (Esophageal and Gastric Multidisciplinary Clinic) for treatment planning who are recommended to receive neoadjuvant treatment followed by surgery at UCCC Metro will be offered enrollment into the study.
- Trial name
- NCT04520867
- Testing
- STRENGTH
- Where
- United States
- Sponsor
- University of Colorado, Denver
Gastric Cancer (GC), Prehabilitation
Multimodal Prehabilitation in Gastric Cancer Patients
This single-arm phase II trial investigates whether a multimodal prehabilitation program can attenuate the postoperative inflammatory response in patients undergoing curative gastric cancer surgery.
- Conditions
- Gastric Cancer (GC), Prehabilitation, Postoperative Inflammation
- Trial name
- PING-P (NCT07839702)
- Testing
- prehabilitation
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- National University Hospital, Singapore
Spine Degeneration, Spine Fusion
Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery
With the extended life expectancy of the Chinese population and improvements in surgery and anesthesia techniques, the number of aged patients undergoing surgery has been increasing annually.
- Conditions
- Spine Degeneration, Spine Fusion, Frailty Syndrome
- Trial name
- PRACTICE (NCT06140797)
- Testing
- Multimodal prehabilitation combined with perioperative ERAS care（PREERAS）
- Where
- 3 sites in China
- Volunteers
- 164 people
- Sponsor
- Xuanwu Hospital, Beijing
Locally Advanced Rectal Cancer
ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Colorectal cancer is a major cause of cancer death in Chile. Many people with rectal cancer that has grown into nearby tissues receive chemotherapy and radiation before surgery.
- Trial name
- ONCO-RET (NCT07453173)
- Testing
- Strength training program
- Where
- Chile
- Volunteers
- 15 people
- Sponsor
- Fundacion Arturo Lopez Perez
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Esophageal Cancer
Prehabilitation on Fitness, Surgical Outcomes and Mitochondria Functionality in Patients With Esophageal Cancer
The most often reported complications of patients with resectable esophageal malignancies are pulmonary (25~57%), which may cause increased intensive care unit utilization, prolonged length of hospital stay, increased mortality…
- Trial name
- NCT04673968
- Testing
- prehabilitation
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- Chang Gung Memorial Hospital
Oesophageal Adenocarcinoma, Chemotherapy Effect
Prehabilitation of Patients With oEsophageal Malignancy Undergoing Peri-operative Treatment
'Pre-EMPT' - A cohort-controlled, interventional study to assess the effects of a pre-emptive exercise programme, or 'prehabilitation', in patients undergoing peri-operative chemotherapy for adenocarcinoma of the lower oesophagus…
- Conditions
- Oesophageal Adenocarcinoma, Chemotherapy Effect, Surgery
- Trial name
- Pre-EMPT (NCT03626610)
- Testing
- Exercise prehabilitation during chemotherapy before surgery
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Pancreatic Cancer, Liver Cancer
Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program
Major surgery is a stressful procedure; good recovery after surgery is important to patients and their doctors. Studies done at the McGill University Health Centre (MUHC) with cancer patients awaiting surgery have shown that…
- Conditions
- Pancreatic Cancer, Liver Cancer, Bile Duct Cancer, Hepatobiliary Cancer
- Trial name
- NCT03475966
- Testing
- Exercise, Nutrition, Relaxation techniques
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Prostate Cancer, Radical Prostatectomy
Impact of a Multimodal Prehabilitation Program Before Robotic-assisted Radical Prostatectomy.
The aim of the study is to verify whether a multimodal prehabilitation program prior to robotic-assisted radical prostatectomy (RARC) contributes to a faster recovery of quality of life after surgery.
- Trial name
- NCT05553327
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clinic of Barcelona
Surgery
Improving Patient Sleep Prior to Elective Surgery
The goal of this clinical trial is to learn if changing sleep behaviour can improve sleep health in patients undergoing prehabilitation before elective surgery.
- Trial name
- NCT06762639
- Testing
- Personalized Sleep Prehabilitation (PSP), Standard of Care Prehabilitation
- Where
- Canada
- Volunteers
- 154 people
- Sponsor
- University Health Network, Toronto
Oral Cancer
AI-based Physiotherapy for Oral Cancer Patients
This study examines the effects of AI-based physiotherapy on oral function, shoulder function, whole-body physical function, and quality of life in oral cancer patients.
- Trial name
- NCT06785051
- Testing
- AI-based physiotherapy, Conventional physiotherapy, Scar management
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Lumbar Spinal Stenosis, Prehabilitation
Effectiveness of Prehabilitation for Patients Undergoing Lumbar Spinal Stenosis Surgery
Lumbar spinal stenosis (LSS) is a common spinal disease that leads to pain and disability. LSS is defined as lower extremity and perineal symptoms (e.g.
- Trial name
- NCT03388983
- Testing
- 6-week prehabilitation
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Bladder Carcinoma
EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy
Currently, the potential value of a multimodal prehabilitation program in bladder cancer has not been extensively studied. The investigators designed the ENHANCE study to assess the effect of a structured multimodal…
- Trial name
- ENHANCE (NCT05480735)
- Testing
- Prehabilitation
- Where
- 8 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- The Netherlands Cancer Institute