Clinical trials: Prenatal Condition
Dermatitis, Atopic
Efficacy Of Antenatal Maternal Supplementation With GOS/Inulin Prebiotics On Atopic Dermatitis Prevalence In High-Risk One-Year-Old Children
Allergies are increasing worldwide affecting 30-40% of the population. Among this, Atopic Dermatitis (AD) is the earliest and the most common manifestation of allergic diseases (prevalence 20%).
- Trial name
- PREGRALL (NCT03183440)
- Testing
- PREBIOTICS
- Where
- 6 sites in France
- Volunteers
- 376 people
- Sponsor
- Nantes University Hospital
Pre-Eclampsia
Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level
Magnesium sulphate is an inorganic salt with multiple therapeutic applications in medicine it has been widely utilized and studied on a diverse set of conditions such as asthma, cardiac arrhythmia and stroke.
- Trial name
- NCT03928691
- Testing
- Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Fetus Disorder
AutoFUSE or First-Trimester Ultrasound Scan
The goal of this clinical trial is to validate the clinical application capabilities of AutoFUSE. The main questions it aims to answer are: Does AutoFUSE reduce the time required to obtain standard planes in first-trimester…
- Trial name
- NCT07601191
- Testing
- AutoFUSE system, Traditional ultrasound scan
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pulmonary Hypertension, Neonatal Hypoxic Respiratory Failure
Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients
The purpose of this study is to determine whether inhaled iloprost is safe and effective in pediatric patients with pulmonary hypertension who are sick in the intensive care unit.
- Conditions
- Pulmonary Hypertension, Neonatal Hypoxic Respiratory Failure, Persistent Pulmonary Hypertension of Newborn, Congenital Heart Defects
- Trial name
- NCT00981591
- Testing
- Iloprost
- Sponsor
- Seattle Children's Hospital
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Meconium Aspiration Syndrome
Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies
The purpose of this study is to evaluate the role of endotracheal suction on the occurrence of meconium aspiration syndrome in depressed meconium stained babies.
- Trial name
- ETMAS (NCT01758822)
- Testing
- No endotracheal suction
- Where
- India
- Volunteers
- 175 people
- Sponsor
- Lady Hardinge Medical College
Infant, Newborn, Respiratory Insufficiency
Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure
This pilot study was a randomized, placebo-controlled, clinical trial to test the safety of using the intravenous form of Prostaglandin E1 (PGE1) in an inhaled form for treatment of hypoxemic respiratory failure in term newborns.
- Conditions
- Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn
- Trial name
- IPGE1 (NCT00598429)
- Testing
- Inhaled Prostaglandin E1
- Where
- 11 sites in United States
- Sponsor
- NICHD Neonatal Research Network
Adverse Pregnancy Outcome
Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project
The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms…
- Trial name
- NCT06004674
- Testing
- Lovenox 40mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Health
Neonatal Meconium Aspiration
Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome
Helium-oxygen mixture(heliox) was suggested to be beneficial in meconium aspiration syndrome in previous studies，but the evidence was limited．The aim of the study was to assess the effectiveness of synchronize intermittent…
- Trial name
- NCT02620891
- Testing
- helium oxygen mixture
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ma Juan
Substance Use Disorders, Prenatal Care
Routine Pregnancy Screening for Women on Opioid Substitution Therapy
Women who take opioid substitution therapy have higher rates of unintended pregnancy, more pregnancies, and a higher risk of pregnancy complications than the general population.
- Conditions
- Substance Use Disorders, Prenatal Care, Pregnancy Outcome
- Trial name
- PREG-O (NCT03489174)
- Testing
- Monthly Pregnancy Screening, Usual Care
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- McMaster University
HIV, Pregnancy
Maternal Determinants of HIV-exposed and HIV-unexposed Fetal Growth, Birth Outcomes and Early Infant Growth
The purpose of this study is to understand how differences in the nutritional status and concentration of hormones and cytokines associated with cachexia in HIV+ and HIV- pregnant women living in a semi-rural and rural region of…
- Conditions
- HIV, Pregnancy, Malnutrition, Cachexia
- Trial name
- NCT01647841
- Where
- Tanzania
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Cornell University
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Iron Deficiency Anemia
Fetal Vascular Hemodynamic Changes in Iron Deficiency Anemia
Iron deficiency anemia is a worldwide medical disorder. So far, it is the most common medical complication in pregnancy specially in developing countries.
- Trial name
- NCT03883841
- Testing
- Iron Sucrose Solution for Injection
- Volunteers
- 60 people
- Sponsor
- Assiut University
Fetal and Neonatal Alloimmune Thrombocytopenia, Long Term Adverse Effects
Neurodevelopmental Outcome After Fetal Neonatal AlloImmune Thrombocytopenia
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease caused by allo-immunisation during pregnancy. If left untreated, FNAIT can lead to severe fetal intracranial haemorrhage.
- Conditions
- Fetal and Neonatal Alloimmune Thrombocytopenia, Long Term Adverse Effects, Neurodevelopmental Abnormality, Intravenous Immunoglobulin Adverse Reaction
- Trial name
- NOFNAIT (NCT04529382)
- Testing
- Cognitive testing (Bayley III, WPPSI III and WISC V)
- Where
- Netherlands
- Volunteers
- 78 people
- Sponsor
- Leiden University Medical Center
Virtual Reality
The Effect of Virtual Reality Glasses on Fetal Movement
When the literature is examined, it is seen that virtual reality glasses are used during medical procedures, have an anxiety-lowering effect and have a reducing effect on the perception of fatigue (20, 7, 10, 11).
- Trial name
- Virtual (NCT05093283)
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Mine Gokduman Keles
Fetal Growth Retardation, Intrauterine Growth Restriction
Fetal Brain Care: Therapies for Brain Neurodevelopment in Fetal Growth Restriction
Singleton pregnancies being diagnosed of fetal growth restriction from 24 to 32.6 weeks of gestation will be randomized to two equally sized groups: maternal oral supplementation with Lactoferrin and DHA (Docosahexaenoic acid) or…
- Trial name
- NCT05038462
- Testing
- Lactoferrin and DHA
- Where
- 6 sites in Spain
- Volunteers
- 304 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Nonorganic Insomnia, Neurodevelopmental Disorders
Better Nights, Better Days for Children With Neurodevelopment Disorders
More than 90% of children with neurodevelopmental disorders (NDD) experience sleep problems, whereas less than 25% of typically developing children experience sleep problems.
- Conditions
- Nonorganic Insomnia, Neurodevelopmental Disorders, Primary Insomnia
- Trial name
- BNBD-NDD (NCT02694003)
- Testing
- BNBD-NDD Intervention
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- IWK Health Centre
Large for Gestational Age Baby, Macrosomia, Fetal
A First Trimester Prediction Model for Large for Gestational Age Infants: a Preliminary Study
Large for gestational age infants (LGA) have increased risks of adverse short-term perinatal outcomes. This study aims to develop a multivariable prediction model for the risk of giving birth to a LGA baby, by using biochemical…
- Trial name
- PreMoLGA (NCT04838431)
- Testing
- Blood sample and ultrasound at first trimester
- Where
- Italy
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Hyperglycemia, Mental Disorder
Explore the Risk Factors for Antenatal Mental Disorders in Pregnant Women With Hyperglycemia
This study aims to investigate the current situation and risk factors of adverse mental disorders in pregnant women with hyperglycemia. it could include any of the following: 18-45 years old pregnant women with hyperglycemia.
- Conditions
- Hyperglycemia, Mental Disorder, Pregnancy Complications
- Trial name
- NCT07003503
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hospital of Southern Medical University
Fetal Distress, Fetal Heart Rate Disorder Nos
A Mixed Methods Study to Explore the Feasibility of a Novel Continuous Fetal Monitoring Device
A stillbirth describes when a baby dies after 24 weeks of pregnancy and before being born. In the UK there are roughly 9 stillbirths every day.
- Trial name
- NCT03370822
- Testing
- MONICA AN24 device
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Manchester