Clinical trials: Prenatal Diagnosis
Preterm Birth
Dexamethasone on Fetal and Uteroplacental Doppler
The current study aims to investigate the effects of dexamethasone exerted on fetal and uteroplacental circulation as measured by Doppler ultrasonography in pregnancies at risk for preterm birth after 24 hours of its…
- Trial name
- NCT02662790
- Testing
- Doppler
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Induction of Labor Affected Fetus / Newborn, Rupture of Membranes Prior to Onset of Labor
Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes
The study aims to evaluate and assess the effectiveness and safety of vaginal administration of isosorbide mono nitrate (IMN) to induce cervical ripening and shorten the interval time between induction and delivery in women…
- Trial name
- NCT03665779
- Testing
- isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- ahmed nagy shaker ramadan
Respiratory Compliance, Functional Residual Capacity
Rescue Antenatal Steroids and Pulmonary Function Tests in Preterm Infants
One course of steroids given to a mother before a premature delivery helps the lungs of the premature infant and decreases breathing problems.
- Conditions
- Respiratory Compliance, Functional Residual Capacity, Pulmonary Function Testing
- Trial name
- NCT00669383
- Testing
- betamethasone
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fetal Death in Utero
Fetal Death in Utero in the Internship Experience of Midwifery Students : an Unavoidable Experience?
Fetal death in utero and the psychological and professional impact it could have on the midwifery student in training. Fetal death in utero corresponds to the spontaneous cessation of cardiac activity, from 14 weeks of…
- Trial name
- MFU (NCT06202508)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Massage Therapy, Pregnancy Related
The Effects of Whole Body Prenatal Massage Therapy During Pregnancy: A Randomized Controlled Experimental Trial
Background: Massage therapy in many parts of the world is used in all periods of pregnancy. Aim: The study aimed to determine the effect of massage therapy during pregnancy on women and their fetuses in a university hospital in…
- Conditions
- Massage Therapy, Pregnancy Related, Fetus Fetus
- Trial name
- NCT05007210
- Testing
- Prenatal massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Preeclampsia, Microvascular Function
Prenatal Aspirin and Postpartum Vascular Function
Preeclampsia is a pregnancy disorder affecting ~5-10% of pregnancies in the United States. Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they…
- Trial name
- NCT05653973
- Testing
- Acetylcholine, Endothelin-1
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Fetal Anomaly
Fetal Brain Ultrasound
The aim of our study is to determine the range of frontal horn sizes (both upside and downside) in healthy fetuses over gestation and to determine how far FHs are from the midline .
- Trial name
- NCT06410391
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
PROMMO Trial: Oral Misoprostol vs IV Oxytocin
This is a prospective, randomized trial looking at the ideal method of labor induction for women with prelabor rupture of membranes and an unfavorable cervical Bishop score.
- Trial name
- PROMMO (NCT04478942)
- Testing
- Misoprostol Oral Product, Intravenous Oxytocin
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Urogenital Abnormalities, Prenatal Disorder
Fetal Ano-genital Distance in 2D Ultrasound.
The purpose of this study is to determine a threshold value of fetal anogenital distance in 2D ultrasound to differentiate male fetuses from female fetuses, starting 18 weeks of gestation and until the due date.
- Conditions
- Urogenital Abnormalities, Prenatal Disorder, Sex Development Disorder
- Trial name
- DAG (NCT03898440)
- Where
- France
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Intrapartum Fever, Chorioamnionitis
Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT)
Chorioamnionitis, or intraamniotic infection, is a common condition affecting 2-5% of all term births. This condition poses well-recognized maternal and neonatal risks, and entails a series of clinical management decisions…
- Trial name
- PARADIP (NCT06950840)
- Testing
- Acetaminophen, dipyrone
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Wolfson Medical Center
Gestational Diabetes Mellitus in Pregnancy
Shear Wave Elastography in Gestational Diabetes Mellitus
Our aim was to investigate and compare placental elasticity by using Shear wave elastography (SWE) in patients with gestational diabetes mellitus (GDM) with and without insulin to non-diabetic controls.
- Trial name
- NCT04455880
- Testing
- SWE is a novel noninvasive dynamic ultrasound technique which refers to measurement for quantitative analysis of tissue elasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Gulsum Uysal
Fetal Growth Abnormality, Amniotic Fluid; Disorder
Serial Third Trimester Abdominal Circumference and Amniotic Fluid Measurements Versus Routine Care
The purpose of this study us to compare the rate of prenatal identification of abnormal fetal growth or amniotic fluid between clinical evaluation of uterine size by symphysis fundal height (SFH) measurements versus point-of-care…
- Trial name
- STAR (NCT03857659)
- Testing
- Point-of-care ultrasound (POC-US), Routine antenatal care, Formal ultrasound
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes
Fetal Cardiac Function Parameters and HbA1c As Screening for Gestational Diabetes Mellitus
This is a prospective cohort study to assess the predictive value of fetal cardiac parameters, the change in fetal cardiac parameters (CFP), HbA1c, and/or the change in HbA1c (ΔHbA1c) for gestational diabetes.
- Trial name
- NCT05019508
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Postpartum Depression
Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in Parturients
Postpartum depression is a common psychological abnormality during the puerperium, which seriously affects maternal and neonatal health.
- Trial name
- NCT05826327
- Testing
- Esketamine, Sufentanil
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Idiopathic Parkinson Disease, Primary Parkinsonism
Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson's Disease
The purpose of clinical trials is to evaluate safety and tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells as a treatment for Patients with Parkinson's disease.
- Trial name
- NCT01860794
- Testing
- Mesencephalic Neuronal Precursor Cells
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Iron Overload
Fetal Parenchymatic Evaluation (Liver, Spleen) Using T2* Sequences
The purpose of this study is to prospectively evaluated the T2* values of normal feti.A standardized scale of T2* values for fetal and neonatal iron organ overload have yet to be reported or devised.
- Trial name
- NCT01121094
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fetal Conditions
The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome
This study will be conducted to show the effect of different degrees of maternal iron deficiency anemia on fetal hemodynamics and neonatal outcome and to evaluate the effect of treatment.
- Trial name
- NCT04016922
- Testing
- Oral ferrous fumerate for Group A, Parenteral iron sucrose for Group B, Compatible blood transfusion for Group C
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Turner Syndrome
Turner Syndrome Prenatal Diagnosis Study
The goal of this study is to compare the features of Turner syndrome in girls who are diagnosed before birth because of fetal concerns versus those who are diagnosed when their mother has an amniocentesis for another reason.
- Trial name
- NCT01668251
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Fetal Growth Restriction, Placenta
Placental Progesterone Membrane Receptors in Fetal Growth Restriction
This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, among pregnancies affected by impaired fetal…
- Conditions
- Fetal Growth Restriction, Placenta, Progesterone Membrane Receptor, PGRMC1
- Trial name
- NCT07701837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samsun University
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
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