Clinical trials: Prenatal Diagnosis
Restless Leg Syndrome
Effects of Static Stretching and Strength Training on Antenatal Restless Leg Syndrome
Restless Legs Syndrome (RLS) is a prevalent sensorimotor disorder affecting pregnant women, particularly in the third trimester, and is associated with sleep disturbances, fatigue and reduced quality of life.
- Trial name
- NCT07642089
- Testing
- Static Stretching, Static Stretching + Strength Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Prolonged Pregnancy
Analysis of the Use of the Fetal Movement Counting for Prolonged Pregnancy.
Prospective mono-centric randomized open-label study (randomization 1: 1, 2 groups) comparing a group of patients who received conventional information to a group of patients who had been sensitized to a fetal active movement…
- Trial name
- COMPTAMAF (NCT04117308)
- Testing
- Classic information, Information by detailed brochure on the fetal active movements account
- Where
- France
- Volunteers
- 278 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Termination of Pregnancy
Obstetric & Pediatric Evolution Following Parental Refusal for Early Termination of Pregnancy Despite Fetal Risk
More and more parents decide to maintain pregnancy which could have been interrupted because of serious fetal pathologies. In this observational study, the investigators examine obstetrical and pediatric evolution of these…
- Trial name
- NCT03393455
- Testing
- not accurate
- Where
- France
- Volunteers
- 211 people
- Sponsor
- University Hospital, Montpellier
Stress, Anxiety
Mindfulness in High Risk Pregnancies
Anxiety, depression and stress are common during pregnancy. These have been found to negatively impact mother and child outcomes.
- Conditions
- Stress, Anxiety, Depression, Mindfulness
- Trial name
- NCT04496115
- Testing
- Mindfulness
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Congenital Heart Disease
Antenatal Investigation of Fetuses With Complex Congenital Heart Defects Using multiOMICS
This study will use multiOMICS study on fetuses with complexe congenital heart defects (CHD) to identify etiological epigenetic factors of these cardiac malformations, related to environmental factors during pregnancy.
- Trial name
- CARDIOMICS (NCT06705543)
- Testing
- multi-omics genetic analyses included exome, multi-omics genetic analyses
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Premature Rupture of Membrane
Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM)
The aim of this study is to compare fetal and maternal outcome in cases of PPROM before 34 weeks versus after 34 weeks.
- Trial name
- NCT03491826
- Testing
- rupture of membrane
- Where
- Egypt
- Volunteers
- 1,011 people
- Sponsor
- sarah mohamed hassan
Fetal Alcohol Spectrum Disorder
Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy?
Urine sample and exhaled Nitric Oxide will analyzed and compared between children diagnosed with Fetal Alcohol Spectrum Disorder and healthy control. Pilot study- 5 children in each group
- Trial name
- NCT03802708
- Testing
- Metabolomic analysis urine sample
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Phenylketonuria, Maternal
A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding
This is a Phase 4 observational study designed to assess the impact of Palynziq ® (pegvaliase) treatment in pregnant women with PKU and on their offspring who were exposed to pegvaliase at any time during pregnancy and…
- Trial name
- PALomino (NCT05579548)
- Testing
- Pegvaliase
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 50 people
- Sponsor
- BioMarin Pharmaceutical
Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region
Perinatal Thoraco-abdomino-pelvic Tumors Study
Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor.
- Trial name
- CONTRAST (NCT06365268)
- Testing
- Collection of data from the patient's medical file
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress
This study recruits women from early-mid pregnancy and later follows their children after birth, tracking both the mother and child until the child reaches at least 4 years of age.
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS (NCT07432217)
- Where
- Singapore
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Non-Stress Test Interpretation, Fetal Well-Being Assessment
Artificial Intelligence, Obstetricians, and Midwives in Non-Stress Test Interpretation
This prospective observational study aims to evaluate and compare the interpretation of antenatal non-stress tests (NSTs) by three artificial intelligence models, three obstetricians, and three midwives.
- Trial name
- NCT07916090
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Genetic Diseases
Prenatal Cytogenetic Diagnosis by Array-Based Copy Number Analysis
The main objective of the multi-centered collaborative study is to evaluate the accuracy, efficacy and clinical advantages of prenatal diagnosis using microarray analysis as compared with conventional karyotyping.
- Trial name
- Microarray (NCT01279733)
- Testing
- Microarray analysis
- Where
- United States
- Volunteers
- 4,450 people, healthy volunteers welcome
- Sponsor
- Columbia University
Fetal Anomalies
Perinatal Diagnosis of GIT Anomalies
fetal gastro intestinal abnormalities can be accurately diagnosed in second trimester
- Trial name
- NCT03514940
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Pregnancy
Néevo®/NéevoDHA® P.L.U.S. Program (Progress Through Learning, Understand & Support)
This is an observational study in which patients who have been prescribed Néevo®/NéevoDHA® are invited to participate in surveys about their pregnancy and experiences with Néevo®/NéevoDHA®.
- Trial name
- NCT01358552
- Testing
- Néevo®/ NéevoDHA®
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Fetal Alcohol Spectrum Disorders
Efficacy Trial of the FMF Connect Mobile Health Intervention
The purpose of this study is to test a new smartphone "app" for parents/caregivers of children with fetal alcohol spectrum disorder (FASD). The app is called Families Moving Forward (FMF) Connect.
- Trial name
- NCT05028517
- Testing
- FMF Connect, Coaching
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Down Syndrome, Fetal Aneuploidy
Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.
- Trial name
- NCT01429389
- Where
- 14 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Sequenom, Inc.
Disorder of Cardiac Function
Myocardial Screening in Fetuses With Congenital Cytomegalovirus (CMV) Infection
BACKGROUND Myocarditis and pericarditis are inflammatory conditions of the heart commonly due to viral or autoimmune etiologies. Human CMV represents one of the leading causes of congenital infections worldwide.
- Trial name
- NCT02787382
- Testing
- echocardiographic examination
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Fetal Growth Retardation
Study Aimed At Improving Height With Genotonorm In Children Born Little And/Or Light With Growth Retardation At The Age
To estimate the percentage of children with serum IGF-1 > 2 standard deviation (compared to a child of the same gender and age and without growth hormone (GH) deficiency) 9 months and 12 months after initiation of GH treatment.
- Trial name
- NCT00174252
- Testing
- Genotonorm (Somatropin)
- Where
- 22 sites in France
- Volunteers
- 57 people
- Sponsor
- Pfizer
Autosomal Recessive Disorder, Aneuploidy
Prenatal Computer-Aided Genetics Education Module
A standard part of obstetrical care is offering prenatal genetic screening. Numerous professional guidelines have emphasized the importance of pretest counseling for prenatal genetic screenings.
- Trial name
- CAGEM (NCT03449225)
- Testing
- Computer-Aided Genetic Education Module
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Intrauterine Growth Retardation, Low Birth Weight
Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso
Low birth weight (LBW; birth weight<2,500g) is the most important determinant of mortality and morbidity in the neonatal period.
- Trial name
- MISAME2 (NCT00909974)
- Testing
- UNIMMAP - multiple micronutrients, Food supplement enriched with multiple micronutrients
- Where
- Burkina Faso
- Volunteers
- 1,302 people
- Sponsor
- Institute of Tropical Medicine, Belgium
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.