Clinical trials: Prenatal Stress
Maternal Psychological Distress, Prenatal Stress
Roo Study on Mom and Baby Well-Being
This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during…
- Conditions
- Maternal Psychological Distress, Prenatal Stress, Infant Development, Functional Neuroimaging
- Trial name
- NCT03809598
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertensive Disorders of Pregnancy (HDP)
Roy Adaptation Model-Based Prenatal Education in Hypertensive Pregnant Women
This study aims to evaluate the effect of Roy Adaptation Model-based prenatal education on perceived stress and quality of life in pregnant women with hypertensive disorders of pregnancy.
- Trial name
- NCT07820306
- Testing
- Roy Adaptation Model-Based Prenatal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy, Fetal Monitoring
Use of In-Home Non-Stress Monitoring Device for Fetal Monitoring: A Nonsignificant Risk (NSR) Device Study
This study evaluates the safety and performance of the PregnaOne System, a non-significant risk (NSR) investigational medical device for in-home fetal monitoring in pregnant women during the third trimester.
- Trial name
- NCT07223996
- Testing
- PregnaOne System
- Where
- 3 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Nestmedic Spolka Akcyjna
Fetal Health, Pregnancy Related
Non Stress Test and Music Performance
Today, many methods are used in the evaluation of intrauterine fetal well-being. Non-stress test (NST) method is mostly used in the non-invasive evaluation of fetal well-being during pregnancy and labor.
- Trial name
- NCT05325840
- Testing
- music terapy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Pregnant Women
Maternal Non-Stress Testing
Percent agreement of vital signs monitoring between the experimental sensor and standard of care monitoring
- Trial name
- NCT04343482
- Testing
- wearable vital signs sensor
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Northwestern University
Fear of Childbirth, Stress
Effect of Antenatal Education on Fear of ChildBirth
The aim of this study was to investigate the effects of antenatal education on birth fear, depression, anxiety, stress, maternal self-efficacy, and mode of delivery in primiparous pregnant women
- Trial name
- NCT05584618
- Testing
- Education
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress - Child Outcomes
This study is a sub-study of Mapping Antenatal Maternal Stress (MAMS). Women previously enrolled in MAMS, their children and their partners/spouses were recruited for a set of more comprehensive assessments to characterise early…
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS-CO (NCT07432243)
- Where
- Singapore
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression, Anxiety
Perinatal Mental Health Study (PMHS) India
The purpose of this observational study is to improve understanding of mental disorders among perinatal women in India.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Somatization
- Trial name
- PMHS (NCT05485701)
- Testing
- Screening tools for common mental disorders
- Where
- 2 sites in India
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Prenatal Stress
Mindfulness Practice in Pregnancy As an Intervention to Decrease Prenatal Stress During the COVID-19 Pandemic
The purpose of the study is to examine whether a simple mindfulness intervention conducted via a virtual platform can reduce stress among pregnant women.
- Trial name
- CALMS (NCT05087329)
- Testing
- Virtual Mindfulness Meditation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fever, Oxidative Stress
Reduction of Intrapartum Fever With Intravenous Acetaminophen
The investigators plan to administer acetaminophen (Tylenol) for the treatment of fever in laboring patients by either an oral or intravenous (IV) route.
- Trial name
- RIFIVA (NCT02625454)
- Testing
- Intravenous Acetaminophen, Oral Acetaminophen
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Richmond University Medical Center
Intrauterine Growth Restriction (IUGR), Oxidative Stress in Neonates
Intrauterine Growth Restriction and Intrauterine Fetal Death
This study investigated whether delaying the clamping of the umbilical cord after birth can reduce harmful oxidative stress in newborns, especially in those who did not grow well during pregnancy (intrauterine growth restriction…
- Conditions
- Intrauterine Growth Restriction (IUGR), Oxidative Stress in Neonates, Umbilical Cord Clamping Time
- Trial name
- NCT07031583
- Testing
- Delayed Umbilical Cord Clamping (DCC), Early Umbilical Cord Clamping (ECC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
Prenatal Stress, Childbirth Self-efficacy
The Effect of Mindfulness-Based Childbirth Education on Fear of Birth, Prenatal Stress, and Childbirth Self-Efficacy
This randomized controlled trial aims to evaluate the effect of mindfulness practices integrated into childbirth preparation education on fear of childbirth, prenatal stress, and childbirth self-efficacy in pregnant…
- Conditions
- Prenatal Stress, Childbirth Self-efficacy, Fear of Childbirth
- Trial name
- NCT07415122
- Testing
- Mindfulness-based childbirth preparation education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Placental Dysfunction, Prenatal Stress
Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes
Explore the associations of prenatal maternal anxiety to placental histologic findings, and the pro-inflammatory, anti-inflammatory, and immunoregulatory cells found in the placenta and determine the effect of maternal anxiety on…
- Trial name
- MOMSPlacenta (NCT04993742)
- Testing
- MOMS Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
PTSD
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce…
- Trial name
- TAPS (NCT05486793)
- Testing
- Written Exposure Therapy (WET), Emotion Focused Supportive Therapy (EFST)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston University
High-Risk Pregnancies
The Effect of Paint-by-Numbers Activity on Stress and Prenatal Attachment in High-Risk Pregnancies
Pregnancy, a physiological state, is defined both as a turning point and a developmental crisis . Pregnancy directly affects maternal and child health, and in cases of complications, it can lead to morbidity and mortality…
- Trial name
- NCT06955312
- Testing
- Experimental
- Volunteers
- 60 people
- Sponsor
- Erzurum Technical University
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fear, Stress (Psychology)
HBM-Based Solution-Focused Birth Program on Fear of Childbirth in Primigravidas
Pregnancy is a period characterized by significant physiological and psychosocial changes, during which women adapt to new roles.
- Conditions
- Fear, Stress (Psychology), Pregnancy
- Trial name
- Primigravida (NCT07549204)
- Testing
- Health Belief Model-Based Solution-Focused Childbirth Preparation Education, Standard Antenatal Education (Pregnancy School)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University